Search Results - "DNA"

DNA, not merely the secret of life part 1 of 2 /

Table of Contents: “…Contents: Hybridization of DNA -- Reciprocal exchange, branched DNA and sticky ends -- Structural DNA nanotechnology -- Polyhedral catenanes -- 2D arrays of tiles -- DNA origami and origami arrays -- 3D self-assembled crystals.…”
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DNA, not merely the secret of life part 2 of 2 /

Table of Contents: “…Contents: Organizing nanoparticles with DNA -- Nanomechanical devices and walkers -- A DNA-based assembly line -- Devices and states that change state in 3D.…”
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Next-generation sequencing technologies

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Statistical genetics in forensic science

Table of Contents: “…Contents: DNA profiles -- Population frequencies -- Three principles of interpretation -- Odds form of Bayes' theorem -- Hardy Weinberg equilibrium -- Relatedness -- Genetic drift.…”
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Techniques to infer admixture using genome-wide autosomal DNA part 1 of 2 /

Table of Contents: “…Contents: Introduction and illustrative simulations -- ADMIXTURE clustering software -- f3-statistics admixture detection software -- Autosomal DNA is used to date admixture -- ALDER/MALDER admixture detection and dating software.…”
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Techniques to infer admixture using genome-wide autosomal DNA part 2 of 2 /

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Genetic methods in the study of neurological diseases the genetic basis of neurological disorders /

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Quantitative CNV testing in molecular diagnostics

Subjects: “…DNA Analysis. 85467…”
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Gene-drives and active genetics introduction to gene-drives and their implications for health and society /

Table of Contents: “…Contents: Gene drives: overview -- CRISPR/Cas9 technology -- CRISPR/Cas9 DNA break repair -- Gene-drive elements spread rapidly in a population -- Active genetics: a new field -- Gene-drive systems -- Active genetics and drive effectors -- DNA repair mechanisms -- Mathematical modeling -- Social and ethical considerations.…”
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Inherited neuropathies

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Next generation sequencing in genetic diagnostics

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The future of CNVs sequence based resolution and links to human disease, (part 2 of 2) /

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Turning genomic junk into treasure genetic engineering with the Sleeping Beauty transposon system /

Table of Contents: “…Contents: Transposons can be viewed as natural DNA transfer vehicles -- Transposons are capable of efficient genomic insertion, similar to integrating viruses -- Transposition can be controlled by conditionally providing the transposase enzyme -- DNA of interest cloned into a transposon-based vector can be utilized for stable genomic insertion in a regulated and highly efficient manner -- Transposition opens up many avenues for genome manipulations in vertebrates -- Generation of transgenic cells and germline-transgenic animals using transposons -- The Sleeping Beauty synthetic transposon -- Clinical applications of the Sleeping Beauty system.…”
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Overview of clinical pharmacology in cancer part 2 of 2 /

Table of Contents: “…Contents: Principles of pharmacodynamics -- Mechanisms of action of anticancer agents -- Evolution from non-specific DNA damagers to targeted therapies -- Integrated pharmacokinetics, dynamics and genomics dose response model.…”
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SARS-COV-2 vaccine development where are we now? /

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The proteomic revolution

Table of Contents: “…Contents: The proteomic revolution -- Proteomics is the best measure of phenotype (biomarkers) -- Slow Off-rate Modified Aptamers (SOMAmers) are breakthrough protein binding reagents -- SOMAmers are multiplexed to perform SOMAscan assay, which measures >1000 proteins in small sample volumes using DNA measurement tools to identify and quantify proteins bound by SOMAmers -- Applications of SOMAscan to date include finding valid protein biomarkers for lung cancer, cardiovascular risk, pre-term birth, pancreatic cancer, mesothelioma, and many other diseases and conditions -- Ability to do comprehensive longitudinal proteomics studies will revolutionize medicine.…”
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Development of an intranasal vaccine for SARS-CoV-2

Table of Contents: “…Contents: General mechanism of action of DNA vaccines -- Adenoviral vectors for DNA delivery to host cells -- Advantages and limitations of intranasal vaccines -- Cellular, mucosal and antibody immunity in the context of SARS-2 -- Stability of AdCOVID at room temperature -- Earliest possible approval of AdCOVID -- How far and how fast can this vaccine then be deployed?…”
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Statistical techniques in human population genetics

Table of Contents: “…Contents: Describe the biological & demographic processes that contribute to genetic diversity -- Describe statistical techniques that use observed DNA patterns to infer these past processes -- Illustrate the types of data used for inferring human history -- Highlight some key findings about human history derived through the use of these techniques.…”
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Protein networks and analysis of global gene expression

“…Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.…”
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Comparing transcriptomes of distant organisms the comparative ENCODE resource, part 1 of 2 /

“…Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.…”
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