Search Results - "hormone"

Hormone mechanisms

Table of Contents: “…Contents: Hormone action via G-protein -- Steroid hormone action in nucleus -- Insulin action in cytosol and nucleus -- Course summary.…”
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Hormonal influence on bone remodeling and its implications for the pathophysiology of osteoporosis

Table of Contents: “…Contents: Birth and fate of osteoblasts and osteoclasts -- Mechanical loading -- Role of osteocytes in mineralization -- Sclerostin -- The cell number concept -- Osteoporosis -- Anti-osteoporotic effects of sex steroids and their cellular mechanisms -- Transcriptional regulation by estrogens -- Glucocorticoid-induced bone disease -- Glucocorticoids induce osteocyte apoptosis -- Effects of thyroid hormones on the skeleton -- Involutional osteoporosis -- Age-dependent skeletal deterioration -- Age-associated oxidative stress -- Future implications.…”
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How to "deconvolute" lung evolution part 2 [of 3]. The evolutionary origins of pulmonary physiology /

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General factors affecting drug metabolism effect of physiological factors and disease, part 1 of 2 /

Table of Contents: “…Contents: Effect of physiological and pathophysiological conditions on drug-metabolizing enzymes (DMEs) -- Role of growth hormones and transcription factors in sex-dependent expression -- Drug clearance and age -- Developmental regulation -- Impact of infection and inflammatory disease on DME expression -- Clinical consequences.…”
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The dynamic interactions between cellular-molecular physiology and the environment part 1, The cellular-molecular approach to evolution as niche construction /

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Glycolysis control

Table of Contents: “…Contents: Control of glycogen breakdown (hormonal and local) -- Hormone amplification -- Control of 3 key enzymes of glycolysis -- Universal principles of enzyme regulation.…”
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General factors affecting drug metabolism effect of physiological factors and disease, part 2 of 2 /

Table of Contents: “…Contents: Effect of physiological and pathophysiological conditions on drug-metabolizing enzymes (DMEs) -- Role of growth hormones and transcription factors in sex-dependent expression -- Drug clearance and age -- Developmental regulation -- Impact of infection and inflammatory disease on DME expression -- Clinical consequences.…”
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Pathways regulating bone resorption

Table of Contents: “…Contents: Formation and activation of osteoclasts -- Osteoporotic bone architecture -- Osteoclastic bone resorption -- Osteoclast motility and its inhibition -- Osteoclast regulation (hormones & other important factors) -- The role of low pH (acidosis) in bone loss -- Hypoxia & control of bone cell function by oxygen tension.…”
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Cholesterol oxidation between health and disease

Table of Contents: “…Contents: Enzymatic and non-enzymatic oxidation of cholesterol -- Increased amount of plasma oxysterols in hyper cholesterolemia -- Pathogenesis of atherosclerosis, Alzheimer's disease, inflammatory bowel disease -- Physiological role of oxysterols of enzymatic origin in: membrane structure and function, synthesis of steroid hormones and bile acids -- Antiviral effects of side-chain oxysterols.…”
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Phosphorylase and the origin of reversible protein phosphorylation

Table of Contents: “…Contents: A historical account of the discovery of reversible protein phosphorylation -- Video clips of the late Edwin Krebs speaking about our early work -- Reversible protein phosphorylation represents one of the most prevalent mechanism by which cellular events are regulated -- Establishment of the first hormonal cascade of successive enzymatic reactions initiated by cAMP.…”
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Super-resolution imaging of GPCR oligomers applications and functional roles /

Table of Contents: “…Contents: Introduction to G Protein-Coupled Receptors (GPCRs) -- Gonadotrophin hormone receptor (GpHR) function -- Role of GPCR oligomerization in vivo through studies of GpHRs -- Single molecule/Super-resolution imaging -- Super-resolution of imaging of GPCRs and GpHRs via PALM -- Applications of PALM to structure/function analysis of GPCR oligomers.…”
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Iron metabolism and innate immunity

Table of Contents: “…Contents: Iron is an essential element for nearly all infectious microorganisms as well as for their plant and animal hosts -- Within hours of infection, animals sequester iron within macrophages as well as in specialized extracellular proteins -- The cellular component of this response causes a marked decrease in extracellular iron concentration -- Hepcidin is a recently characterized peptide that functions as the homeostatic iron-regulatory hormone and as the mediator of inflammatory iron sequestration -- It acts by binding to the sole known cellular iron exporter, ferroportin, and inducing its internalization and degradation -- Pathological regulation or dysregulation of the hepcidin-ferroportin axis is responsible for a number of common iron-related disorders including anemia of inflammation, hereditary hemochromatosis and iron-loading anemias.…”
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