Search Results - "essentialism"

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  1. 1

    O-GlcNAc, an essential regulator of numerous cellular pathways

    Published 2014
    “…O-linked beta-N-acetylglucosamine, an essential regulator of numerous cellular pathways…”
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    Series
    Electronic Video
  2. 2

    O-GlcNAc, an essential regulator of numerous cellular pathways

    Published 2014
    “…O-linked beta-N-acetylglucosamine, an essential regulator of numerous cellular pathways…”
    Get full text
    Series
    Electronic Video
  3. 3

    O-GlcNAc, an essential regulator of numerous cellular pathways

    Published 2014
    “…O-linked beta-N-acetylglucosamine, an essential regulator of numerous cellular pathways…”
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    Series
    Electronic Video
  4. 4

    Photoreceptor protection significance of docosanoids and elovanoids. Part 1 of 2, docosahexaenoic acid (DHA) /

    Published 2019
    Table of Contents: “…Contents: Biosynthesis of docosanoids -- Essential fatty acids -- Neuroprotective bioactivity during oxidative stress -- AdipoR1 as a regulatory switch of the DHA.…”
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    Series
    Electronic Video
  5. 5

    Biogenesis of cellular iron-sulfur proteins part II, the essential role of mitochondria and the CIA machinery /

    Published 2018
    “…Biogenesis of cellular iron-sulfur proteins. Part 2, The essential role of mitochondria and the CIA machinery…”
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    Series
    Electronic Video
  6. 6

    Biogenesis of cellular iron-sulfur proteins part II, the essential role of mitochondria and the CIA machinery /

    Published 2018
    “…Biogenesis of cellular iron-sulfur proteins. Part 2, The essential role of mitochondria and the CIA machinery…”
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    Series
    Electronic Video
  7. 7

    Biogenesis of cellular iron-sulfur proteins part II, the essential role of mitochondria and the CIA machinery /

    Published 2018
    “…Biogenesis of cellular iron-sulfur proteins. Part 2, The essential role of mitochondria and the CIA machinery…”
    Get full text
    Series
    Electronic Video
  8. 8

    Photoreceptor protection significance of docosanoids and elovanoids. Part 1 of 2, docosahexaenoic acid (DHA) /

    Published 2019
    Table of Contents: “…Contents: Biosynthesis of docosanoids -- Essential fatty acids -- Neuroprotective bioactivity during oxidative stress -- AdipoR1 as a regulatory switch of the DHA.…”
    Get full text
    Series
    Electronic Video
  9. 9

    Photoreceptor protection significance of docosanoids and elovanoids. Part 1 of 2, docosahexaenoic acid (DHA) /

    Published 2019
    Table of Contents: “…Contents: Biosynthesis of docosanoids -- Essential fatty acids -- Neuroprotective bioactivity during oxidative stress -- AdipoR1 as a regulatory switch of the DHA.…”
    Get full text
    Series
    Electronic Video
  10. 10

    Designing proteins with life sustaining activities part 1 of 2 /

    Published 2017
    Table of Contents: “…Contents: Protein design & synthetic biology -- Designing novel proteins using a hybrid approach -- Combinatorial libraries of novel proteins -- Folding of novel proteins into stable structures -- Biochemical activity of novel proteins in vitro (binding & catalysis) -- Essential biological functions provided by novel proteins in vivo.…”
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    Series
    Electronic Video
  11. 11

    Designing proteins with life sustaining activities part 1 of 2 /

    Published 2017
    Table of Contents: “…Contents: Protein design & synthetic biology -- Designing novel proteins using a hybrid approach -- Combinatorial libraries of novel proteins -- Folding of novel proteins into stable structures -- Biochemical activity of novel proteins in vitro (binding & catalysis) -- Essential biological functions provided by novel proteins in vivo.…”
    Get full text
    Series
    Electronic Video
  12. 12

    Designing proteins with life sustaining activities part 1 of 2 /

    Published 2017
    Table of Contents: “…Contents: Protein design & synthetic biology -- Designing novel proteins using a hybrid approach -- Combinatorial libraries of novel proteins -- Folding of novel proteins into stable structures -- Biochemical activity of novel proteins in vitro (binding & catalysis) -- Essential biological functions provided by novel proteins in vivo.…”
    Get full text
    Series
    Electronic Video
  13. 13

    Polycomb epigenetic mechanisms Part 2 of 2, methylation of DNA /

    Published 2017
    Table of Contents: “…Contents: PRC2 has an untargeted global function -- Chromatin immunoprecipitation (ChIP-seq) profiles -- H3K27 methylation -- The CBP/p300 acetylase complex -- The TRR complex (MLL3,4 in mammals) -- The DNA accessibility model -- How do PcG complexes repress? -- The essential role of canonical PRC1 -- Links between PRC1 and PRC2 -- The bivalent state.…”
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    Series
    Electronic Video
  14. 14

    Polycomb epigenetic mechanisms Part 2 of 2, methylation of DNA /

    Published 2017
    Table of Contents: “…Contents: PRC2 has an untargeted global function -- Chromatin immunoprecipitation (ChIP-seq) profiles -- H3K27 methylation -- The CBP/p300 acetylase complex -- The TRR complex (MLL3,4 in mammals) -- The DNA accessibility model -- How do PcG complexes repress? -- The essential role of canonical PRC1 -- Links between PRC1 and PRC2 -- The bivalent state.…”
    Get full text
    Series
    Electronic Video
  15. 15

    Polycomb epigenetic mechanisms Part 2 of 2, methylation of DNA /

    Published 2017
    Table of Contents: “…Contents: PRC2 has an untargeted global function -- Chromatin immunoprecipitation (ChIP-seq) profiles -- H3K27 methylation -- The CBP/p300 acetylase complex -- The TRR complex (MLL3,4 in mammals) -- The DNA accessibility model -- How do PcG complexes repress? -- The essential role of canonical PRC1 -- Links between PRC1 and PRC2 -- The bivalent state.…”
    Get full text
    Series
    Electronic Video
  16. 16

    Purinergic neuron-to-glia signaling in the enteric nervous system

    Published 2014
    Table of Contents: “…Contents: The enteric nervous system is an extensive neural network that is housed in the wall of the gut and provides local control of gut functions -- The environment within enteric ganglia is similar to brain tissue and only includes neurons and glia -- Enteric glia a unique type of peripheral glia that share many similarities with astrocytes in the brain -- Enteric glia are implicated in a number of essential processes in the intestine but recent evidence suggests that enteric glia are particularly integral in the regulation of purinergic communication between neurons in the enteric nervous system.…”
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    Series
    Electronic Video
  17. 17

    Purinergic neuron-to-glia signaling in the enteric nervous system

    Published 2020
    Table of Contents: “…Contents: The enteric nervous system is an extensive neural network that is housed in the wall of the gut and provides local control of gut functions -- The environment within enteric ganglia is similar to brain tissue and only includes neurons and glia -- Enteric glia a unique type of peripheral glia that share many similarities with astrocytes in the brain -- Enteric glia are implicated in a number of essential processes in the intestine but recent evidence suggests that enteric glia are particularly integral in the regulation of purinergic communication between neurons in the enteric nervous system.…”
    Get full text
    Series
    Electronic Video
  18. 18

    Purinergic neuron-to-glia signaling in the enteric nervous system

    Published 2020
    Table of Contents: “…Contents: The enteric nervous system is an extensive neural network that is housed in the wall of the gut and provides local control of gut functions -- The environment within enteric ganglia is similar to brain tissue and only includes neurons and glia -- Enteric glia a unique type of peripheral glia that share many similarities with astrocytes in the brain -- Enteric glia are implicated in a number of essential processes in the intestine but recent evidence suggests that enteric glia are particularly integral in the regulation of purinergic communication between neurons in the enteric nervous system.…”
    Get full text
    Series
    Electronic Video
  19. 19

    Iron metabolism and innate immunity

    Published 2009
    Table of Contents: “…Contents: Iron is an essential element for nearly all infectious microorganisms as well as for their plant and animal hosts -- Within hours of infection, animals sequester iron within macrophages as well as in specialized extracellular proteins -- The cellular component of this response causes a marked decrease in extracellular iron concentration -- Hepcidin is a recently characterized peptide that functions as the homeostatic iron-regulatory hormone and as the mediator of inflammatory iron sequestration -- It acts by binding to the sole known cellular iron exporter, ferroportin, and inducing its internalization and degradation -- Pathological regulation or dysregulation of the hepcidin-ferroportin axis is responsible for a number of common iron-related disorders including anemia of inflammation, hereditary hemochromatosis and iron-loading anemias.…”
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    Series
    Electronic Video
  20. 20

    Iron metabolism and innate immunity

    Published 2020
    Table of Contents: “…Contents: Iron is an essential element for nearly all infectious microorganisms as well as for their plant and animal hosts -- Within hours of infection, animals sequester iron within macrophages as well as in specialized extracellular proteins -- The cellular component of this response causes a marked decrease in extracellular iron concentration -- Hepcidin is a recently characterized peptide that functions as the homeostatic iron-regulatory hormone and as the mediator of inflammatory iron sequestration -- It acts by binding to the sole known cellular iron exporter, ferroportin, and inducing its internalization and degradation -- Pathological regulation or dysregulation of the hepcidin-ferroportin axis is responsible for a number of common iron-related disorders including anemia of inflammation, hereditary hemochromatosis and iron-loading anemias.…”
    Get full text
    Series
    Electronic Video