Search Results - "DNA"
Suggested Topics within your search.
Suggested Topics within your search.
- metabolism
- genetics 14
- physiology 13
- Proteins 10
- Gene Expression Regulation 8
- Chromatin 7
- Transcription Factors 7
- DNA 5
- Genetic transcription 5
- Transcription, Genetic 5
- pathology 5
- Cancer 4
- DNA Methylation 4
- DNA, Mitochondrial 4
- Epigenesis 4
- Epigenesis, Genetic 4
- Genetic regulation 4
- Histones 4
- Metabolism 4
- Mitochondria 4
- Neoplasms 4
- methods 4
- Cell Cycle 3
- DNA-Binding Proteins 3
- Gene expression 3
- Genetic aspects 3
- Genomics 3
- Mitochondrial pathology 3
- Molecular aspects 3
- Pathophysiology 3
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DNA replication
Published 2007Table of Contents: “…Contents: Chemical composition of DNA -- Chargaff's rule -- DNA structure -- Base pairing -- Semiconservative DNA replication -- Mechanism of DNA replication -- Semi-discontinuous DNA replication -- DNA replication is catalyzed by the cooperative action of a number of proteins: what we know -- DNA polymerase structure -- Structure of phage T7 DNA polymerase -- Chemical reaction catalyzed by DNA polymerases -- Metal ions play an essential role in DNA synthesis -- DNA synthesis has to be efficient and accurate -- Rates of correct and incorrect nucleotide addition -- How are errors corrected? …”
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2
DNA methylation patterns in mammals
Published 2011Table of Contents: “…Contents: The distribution of cytosine methylation in mammals -- Influences on targeting of cytosine methylation -- Demethylation of DNA -- Protection against cytosine methylation -- Global and developmental dynamics of cytosine methylation -- Patterns of change of cytosine methylation in disease -- Influence of DNA sequence polymorphism on cytosine methylation variability -- Future directions.…”
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3
Polycomb epigenetic mechanisms Part 2 of 2, methylation of DNA /
Published 2017Table of Contents: “…Contents: PRC2 has an untargeted global function -- Chromatin immunoprecipitation (ChIP-seq) profiles -- H3K27 methylation -- The CBP/p300 acetylase complex -- The TRR complex (MLL3,4 in mammals) -- The DNA accessibility model -- How do PcG complexes repress? …”
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4
Nucleotide dependent functioning of bacterial enhancer binding proteins, activators of sigma54 RNA polymerase
Published 2016Table of Contents: “…Contents: Understanding the origins of nucleotide driven conformational change -- Molecular motors powered by ATP -- ATPases belonging to the AAA protein family -- PspF from E.coli -- Phage shock genes -- ATP transition state analogue ADPAlF -- X-ray crystallographic structural analysis -- Initiation of conformational changes -- Role of structural changes in sigma54 subunit -- Formation of open promoter complexes -- Changes in DNA binding properties of sigma54 -- Structural organisation of the RNAP holoenzyme.…”
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5
Mitochondrial disorders and neurodegeneration
Published 2019Table of Contents: “…Contents: Mitochondrial structure and function -- Oxidative phosphorylation -- Mitochondrial DNA (mtDNA) structure, replication and maternal inheritance -- Diseases caused by mutations in mtDNA and therapy -- Diseases caused by mutations in nuclear genes coding for mitochondrial proteins.…”
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6
Chromatin architecture and alterations in the control of gene regulation
Published 2007Subjects: Get full text
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7
O-GlcNAc, an essential regulator of numerous cellular pathways
Published 2014Subjects: Get full text
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8
The aging of mitotic cells regeneration and aging /
Published 2014Subjects: Get full text
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9
Role of polycomb proteins in gene transcription, stem cell and human diseases
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10
The Myc transcription factor network
Published 2023Table of Contents: “…Contents: Myc plays a broad role in cellular functions -- Deregulation of Myc is associated with many cancers -- Myc and Mxd proteins heterodimerize with Max, bind DNA, and activate or repress transcription through recruitment of co-regulator complexes that in turn influence chromatin modifications -- Myc family proteins are highly conserved and regulate cell growth by binding to many genes involved in translation and metabolism -- Myc also has functions unrelated to transcription -- Update talk: The MYC transcription factor network -- Update talk: Interactions of MYC with other cellular proteins -- Update talk: Topologically Associated Domains (TADs) -- Update talk: Transcriptional functions of MYC -- Update talk: Proximal MYC network -- Update talk: New approaches to inhibiting MYC activity.…”
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11
Turning genomic junk into treasure genetic engineering with the Sleeping Beauty transposon system /
Published 2014Table of Contents: “…Contents: Transposons can be viewed as natural DNA transfer vehicles -- Transposons are capable of efficient genomic insertion, similar to integrating viruses -- Transposition can be controlled by conditionally providing the transposase enzyme -- DNA of interest cloned into a transposon-based vector can be utilized for stable genomic insertion in a regulated and highly efficient manner -- Transposition opens up many avenues for genome manipulations in vertebrates -- Generation of transgenic cells and germline-transgenic animals using transposons -- The Sleeping Beauty synthetic transposon -- Clinical applications of the Sleeping Beauty system.…”
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12
Mitochondrial and lysosomal dysfunction in the pathogenesis of Parkinson's disease
Published 2014Table of Contents: “…Contents: Pathogenesis of Parkinson's disease (PD) -- Mitochondria (biochemistry, DNA, proteins, turnover) -- Oxidative phosphorylation and respiratory chain -- Fraction of deleted mtDNA in substantia nigra (SN) -- Mitochondrial complex I deficiency in PD -- PARK loci -- The role of mitophagy in mitochondrial turnover -- Common pathways underlying PD pathogenesis -- Ageing and PD pathogenesis -- Autosomal mitochondrial diseases -- POLG mutations -- Alpha-synuclein (SNCA) and mitochondria -- Autophagy, lysosomal dysfunction and Glucocerebrosidase (GCase) -- Gaucher disease -- Chaperone-mediated autophagy: LAMP-2A -- GBA mutations -- DAT density and disease progression in PD -- DaTScan in genetic PD -- GCase-SNCA as a target for PD -- GBA & GBA-SNCA pathway as targets for PD therapies.…”
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13
Vitiligo in vivo and in vitro evidence for epidermal ROS/RNS-mediated regulation/dysregulation /
Published 2014Table of Contents: “…Contents: Role of inherited vs. induced (tanning) skin colour -- Enhanced pigmentation after sun exposure -- Vitiligo and its characteristics (inherited skin colour loss) -- Correct diagnosis of vitiligo via characteristic fluorescence -- Use of Wood's light for differential diagnosis -- Cause and pathogenesis of vitiligo -- Oxidation and nitration of proteins and peptides in vitiligo and their effects -- DNA damage, T-cell response & p53 in vitiligo -- Treating vitiligo: Reducing oxidation and repigmentation.…”
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14
Overview of clinical pharmacology in cancer part 2 of 2 /
Published 2017Table of Contents: “…Contents: Principles of pharmacodynamics -- Mechanisms of action of anticancer agents -- Evolution from non-specific DNA damagers to targeted therapies -- Integrated pharmacokinetics, dynamics and genomics dose response model.…”
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Mitochondria and ageing in model systems
Published 2018Table of Contents: “…Contents: Mitochondria function/dysfunction and related outcomes -- Metabolic rate theory of aging -- Beneficial effects of caloric restriction -- ROS production and oxidative stress effect on aging -- Free radical theory of aging -- Mitochondrial DNA mutations phenotypes.…”
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17
The transcription factor NF-Kappa B an evolutionarily conserved mediator of immune and inflammatory responses /
Published 2015Subjects: Get full text
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18
Skin epigenetics how chromatin regulators orchestrate skin functions /
Published 2014Table of Contents: “…-- Genes encoding keratinocyte-specific proteins -- Molecular signature of epidermal layers -- Levels of epigenetic regulation -- DNA methylation and hydroxymethylation -- DNA methylation influence on the epidermis -- Post-translational histone/covalent modifications -- Histone acetylation/de-acetylation -- Polycomb-repressive complex -- Polycomb and Trithorax play antagonistic roles -- ATP-dependent chromatin remodeling -- Non-coding RNA-dependent mechanisms -- Nucleus: storage, replication of genetic material -- Topological gene interactomes -- Morphogenesis of the epidermis -- Epidermal differentiation complex -- EDC and Lor relocation to nuclear interior -- p63 and Brg1 ablation results in retention of EDC -- Genome organizer AT-rich binding Satb1 protein -- Transcription factor and epigenetic mechanisms -- Future directions of epigenetic research.…”
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19
Protein networks and analysis of global gene expression
Published 2007“…Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.…”
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Pre-mRNA splicing
Published 2007“…Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.…”
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