Search Results - "yeast"
Suggested Topics within your search.
Suggested Topics within your search.
- genetics
- metabolism 6
- Saccharomyces cerevisiae 5
- physiology 4
- Biological models 3
- Gene Expression Regulation 3
- Gene Expression Regulation, Fungal 3
- Genetic aspects 3
- Models, Biological 3
- methods 3
- Cellular signal transduction 2
- Chromatin 2
- Genetic regulation 2
- Genetics 2
- Mitochondria 2
- Models, Genetic 2
- Molecular aspects 2
- Neoplasms 2
- Schizosaccharomyces 2
- Schizosaccharomyces pombe 2
- Systems Biology 2
- Systems biology 2
- Transcription Factors 2
- Yeast fungi 2
- Age Factors 1
- Aging 1
- Aneuploidy 1
- Animal models 1
- Aurora Kinases 1
- Bioinformatics 1
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1
Yeast studies on ageing
Published 2016Table of Contents: “…Contents: History of studies on yeast ageing -- Senescence factor, molecular memory, and age locus -- Mitochondria and ageing -- Age asymmetry and cell quality control -- Epigenetic gene regulation and ageing -- Genome instability as a cause of ageing -- Replicative and chronological lifespans -- Nutrient effects on lifespan -- Ageing in the wild.…”
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2
Gene silencing in budding yeast
Published 2016Table of Contents: “…Contents: Gene silencing: an epigenetic phenomenon -- Chromatin remodeling: heterochromatin and euchromatin -- Silent chromatin in budding yeast: mating-type loci -- Silent information regulation: telomeric genes and Sir proteins.…”
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3
Chromosome bi-orientation in yeast
Published 2022Table of Contents: “…-- Failure to bi-orient a chromosome will lead to mis-segregation/aneuploidy -- Modes of sister chromatid attachment to spindle microtubules -- The budding yeast (Saccharomyces cerevisiae) as a model for studying chromosome bi-orientation -- Monitoring sister centromeres on individual yeast chromosomes -- Kinetochore capture -- Achieving chromosome bi-orientation: mechanisms -- Geometry-dependent mechanism or a correction mechanism? …”
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4
MAPK signalling regulation and cancer lessons from fission yeast /
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5
Impact of systems biology on metabolic engineering
Published 2014Table of Contents: “…Contents: The biorefinery concept -- The process of metabolic engineering (ME) -- Approaches in systems biology (SB) -- Genome scale metabolic models (GEMs) -- Using SB to design succinic acid production in yeast -- Using SB to compare metabolism of yeast strains -- Using SB to compare penicillin producing in yeast strains -- Inverse metabolic engineering -- Using inverse ME to improve galactose utilization in yeast -- Mechanisms of evolutionary trade-offs.…”
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6
Protein networks and analysis of global gene expression
Published 2007Table of Contents: “…Contents: A paradigm shift: from databases of protein sequences to protein interactions -- Technologies for measuring interactions -- Chromatin immunoprecipitation (ChIP) -- Yeast Two Hybrid (Y2H) technology -- Mass spectrometry based approaches -- Methods for querying protein networks with gene expression profiles -- Systematic validation of protein network models using gene deletions -- Cytoscape open-source software for network modeling and visualization -- Methods for network comparison across species -- Application to discover conserved protein complexes among the networks of yeast, worm, fly and Plasmodium -- Methods for querying protein networks to explain genetic (synthetic lethal) interactions -- Future directions: how network queries will enable systems biology.…”
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7
Computational modelling of GPCR signalling dynamics
Published 2020Table of Contents: “…Contents: GPCRs signalling kinetics can be modelled using simple equations -- Link between computational modelling and pharmacology -- Yeast are excellent system for computational models -- RGS proteins show non-intuitive activity -- Kinetic models of GPCRs can model agonist bias.…”
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8
Mechanisms of mitochondrial fusion and fission
Published 2007Table of Contents: “…Contents: Mitochondrial ultrastructure -- Mitochondrial organization in the cytosol -- Mitochondria-shaping proteins -- Dynamins and the dynamin superfamily -- Control of mitochondrial shape in yeast -- Control of mitochondrial morphology in mammals -- Mitochondrial fusion and the transmission of mitochondrial DNA -- Changes in mitochondrial ultrastructure during apoptosis -- Mitochondrial fragmentation during apoptosis -- Cristae remodeling and OPA1.…”
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9
Enhancer malfunction in cancer
Published 2014Table of Contents: “…Contents: MLL genes and their pathogenic translocations -- Yeast, mammalian and Drosophila systems for studying leukaemia pathogenesis -- Proteins and protein complexes that regulate chromatin modifications, transcription initiation, and transcription elongation -- What is the function of MLL? …”
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10
Deciphering neurodegeneration models and methods /
Published 2014Table of Contents: “…Contents: Deciphering Neurodegeneration: Models and Methods -- The challenge of neurodegeneration -- Huge diversity in cell types -- Nature versus nurture -- Reductionism versus systems biology -- Cellular models -- Yeast -- Primary cells -- Cell lines -- Stem cells -- Model organisms -- Caenorhabditis elegans -- Drosophila melanogaster -- Zebrafish -- Danio rerio -- Rodents -- Molecular biology approaches -- Knock out and knock in -- Genomic editing -- RNAi -- Overexpression -- Gene expression -- rtPCR -- Microarrays -- RNAseq -- Protein analysis -- Immunoblot -- ELISA -- Mass spec and proteomics -- Microscopy -- Immunocytochemistry -- Live cell imaging -- Electrophysiology.…”
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11
Intrinsically unstructured proteins regulation and disease /
Published 2012Table of Contents: “…Contents: Regulatory genomics and systems biology -- Intrinsically unstructured proteins (IUPs): structural and biophysical advantage -- Functional advantage -- Thermodynamic and kinetic advantage -- Conformational advantage -- Identification of IUPs -- Functions of IUPs -- Disadvantages of unstructured regions -- Unstructured regions in proteins -- Cells minimize the risks of unstructured proteins -- Tight regulation of IUPs -- Key regulatory events affecting protein availability -- IUPs in yeast -- Gene-ontology functional enrichment analysis -- Genome-scale datasets on transcript availability -- Transcripts encoding IUPs are tightly controlled -- Mechanisms affecting transcript stability -- Genome-scale datasets on protein availability -- IUPs are tightly controlled at the translational level -- PEST sequences -- Aggregation prone IUPs: more tightly regulated -- Control calculation -- Tight regulation of IUPs is evolutionarily conserved -- Control of IUP affects signaling fidelity/regulation -- Control of specific IUP affects protein aggregation.…”
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