Search Results - "proteins"

G proteins and GPCRs in cancer

Table of Contents: “…Contents: G proteins and GPCRs as oncogenes -- G proteins and GPCRs in tumorigenesis -- GPCR signalling -- GPCRs and metastasis -- GPCRs and tumor-induced angiogenesis -- GPCR targeting and immunotherapies.…”
Get full text
Series

G proteins and GPCRs in cancer

Table of Contents: “…Contents: G proteins and GPCRs as oncogenes -- G proteins and GPCRs in tumorigenesis -- GPCR signalling -- GPCRs and metastasis -- GPCRs and tumor-induced angiogenesis -- GPCR targeting and immunotherapies.…”
Get full text
Series

G proteins and the biology of depression and antidepressants

Table of Contents: “…Contents: Depression -- Antidepressant drug targets -- G protein signaling -- GPCR -- Gs alpha lipid raft localization and antidepressant treatment -- Gs alpha Acylation status and lipid raft localization -- Gs alpha palmitoylation status and lipid raft localization -- Blood biomarkers for depression.…”
Get full text
Series

G proteins and the biology of depression and antidepressants

Table of Contents: “…Contents: Depression -- Antidepressant drug targets -- G protein signaling -- GPCR -- Gs alpha lipid raft localization and antidepressant treatment -- Gs alpha Acylation status and lipid raft localization -- Gs alpha palmitoylation status and lipid raft localization -- Blood biomarkers for depression.…”
Get full text
Series

Adapting proteostasis to ameliorate aggregation-associated amyloid diseases

Table of Contents: “…Contents: Protein folding, misfolding, aggregation -- The proteostasis network and its regulation -- Gain and loss of function diseases -- The transthyretin (TTR) amyloidosis -- Kinetic stabilizers & clinical trial results -- Tafamidis & Diflunisal: evidence for the amyloid hypothesis -- Improving protein misfolding/aggregation diseases -- The unfolded protein response (UPR) and its arm-selective activators -- ATF6 activation & reduction of TTR mutant -- Clinical trials in amyloidosis with cardiac involvement.…”
Get full text
Series

Adapting proteostasis to ameliorate aggregation-associated amyloid diseases

Table of Contents: “…Contents: Protein folding, misfolding, aggregation -- The proteostasis network and its regulation -- Gain and loss of function diseases -- The transthyretin (TTR) amyloidosis -- Kinetic stabilizers & clinical trial results -- Tafamidis & Diflunisal: evidence for the amyloid hypothesis -- Improving protein misfolding/aggregation diseases -- The unfolded protein response (UPR) and its arm-selective activators -- ATF6 activation & reduction of TTR mutant -- Clinical trials in amyloidosis with cardiac involvement.…”
Get full text
Series

Adapting proteostasis to ameliorate aggregation-associated amyloid diseases

Table of Contents: “…Contents: Protein folding, misfolding, aggregation -- The proteostasis network and its regulation -- Gain and loss of function diseases -- The transthyretin (TTR) amyloidosis -- Kinetic stabilizers & clinical trial results -- Tafamidis & Diflunisal: evidence for the amyloid hypothesis -- Improving protein misfolding/aggregation diseases -- The unfolded protein response (UPR) and its arm-selective activators -- ATF6 activation & reduction of TTR mutant -- Clinical trials in amyloidosis with cardiac involvement.…”
Get full text
Series

CML genetic paradigm of targeted therapy, part 2 of 2 /

Subjects: Get full text
Series

Discovery of schizophrenia drug targets from DISC1 mechanisms

Table of Contents: “…Contents: Discovery of DISC1 -- Potential Therapeutics strategies based on the structure and motif of DISC1 protein -- DISC1-associated pathways as drug targets -- Molecular complexities of DISC1.…”
Get full text
Series (Drug discovery and development in the neurosciences)
Series (Small molecule drug discovery).

CML genetic paradigm of targeted therapy, part 1 of 2 /

Subjects: Get full text
Series

CML genetic paradigm of targeted therapy, part 2 of 2 /

Subjects: Get full text
Series

CML genetic paradigm of targeted therapy, part 2 of 2 /

Subjects: Get full text
Series

Complement in PNH and other hemolytic anaemias part 2 of 3 /

Table of Contents: “…Contents: Genetically defective regulation (somatic) -- PNH: complement–mediated hemolysis -- Flow-cytometry analysis of PNH red cells -- Proteins in the lipid bilayer: GPI-anchors -- Mutations in the PIG-A gene -- Proteins deficient on PNH blood cells -- Mechanism of intravascular hemolysis in PNH -- Mechanism of action of CD59.…”
Get full text
Series

GPCRs and pain

Subjects: Get full text
Series

Discovery of schizophrenia drug targets from DISC1 mechanisms

Table of Contents: “…Contents: Discovery of DISC1 -- Potential Therapeutics strategies based on the structure and motif of DISC1 protein -- DISC1-associated pathways as drug targets -- Molecular complexities of DISC1.…”
Get full text
Series (Drug discovery and development in the neurosciences)
Series (Small molecule drug discovery).

Discovery of schizophrenia drug targets from DISC1 mechanisms

Table of Contents: “…Contents: Discovery of DISC1 -- Potential Therapeutics strategies based on the structure and motif of DISC1 protein -- DISC1-associated pathways as drug targets -- Molecular complexities of DISC1.…”
Get full text
Series (Drug discovery and development in the neurosciences)
Series (Small molecule drug discovery).

Imatinib as a paradigm of targeted cancer therapies

Subjects: Get full text
Series (Signal transduction via protein tyrosine kinase receptors)
Series (Small molecule drug discovery)

Complement as a therapeutic target

Subjects: Get full text
Series (Complement system)
Series (Macular degeneration)

CML genetic paradigm of targeted therapy, part 1 of 2 /

Subjects: Get full text
Series

CML genetic paradigm of targeted therapy, part 1 of 2 /

Subjects: Get full text
Series