Search Results - "DNA"

Quantitative CNV testing in molecular diagnostics

Subjects: “…DNA Analysis. 85467…”
Get full text
Series

Inherited neuropathies

Subjects: Get full text
Series

Non-invasive prenatal diagnosis

Table of Contents: “…Contents: Overview of plasma nucleic acids -- Discovery and basic biology of circulating fetal DNA -- T21 detection from maternal plasma -- T13/18 detection from maternal plasma -- Fetal genome scanning -- Targeted sequencing from maternal plasma -- Size analysis of plasma DNA.…”
Get full text
Series

Circulating nucleic acids as biomarkers in cancer patients

Table of Contents: “…Contents: Circulating Nucleic Acids -- Advantages of Serum/Plasma DNA vs. Tumor Tissue DNA -- Circulating DNA in patients with benign disease and malignant tumors -- Circulating microRNAs in cancer patients -- Associations between Circulating Tumor Cells and cell-free tumor DNA in cancer patients.…”
Get full text
Series

Next generation sequencing in genetic diagnostics

Subjects: Get full text
Series

Vitiligo in vivo and in vitro evidence for epidermal ROS/RNS-mediated regulation/dysregulation /

Table of Contents: “…Contents: Role of inherited vs. induced (tanning) skin colour -- Enhanced pigmentation after sun exposure -- Vitiligo and its characteristics (inherited skin colour loss) -- Correct diagnosis of vitiligo via characteristic fluorescence -- Use of Wood's light for differential diagnosis -- Cause and pathogenesis of vitiligo -- Oxidation and nitration of proteins and peptides in vitiligo and their effects -- DNA damage, T-cell response & p53 in vitiligo -- Treating vitiligo: Reducing oxidation and repigmentation.…”
Get full text
Series

The proteomic revolution

Table of Contents: “…Contents: The proteomic revolution -- Proteomics is the best measure of phenotype (biomarkers) -- Slow Off-rate Modified Aptamers (SOMAmers) are breakthrough protein binding reagents -- SOMAmers are multiplexed to perform SOMAscan assay, which measures >1000 proteins in small sample volumes using DNA measurement tools to identify and quantify proteins bound by SOMAmers -- Applications of SOMAscan to date include finding valid protein biomarkers for lung cancer, cardiovascular risk, pre-term birth, pancreatic cancer, mesothelioma, and many other diseases and conditions -- Ability to do comprehensive longitudinal proteomics studies will revolutionize medicine.…”
Get full text
Series

Mismatch repair deficient cancers diagnosis, treatment and prevention

Subjects: Get full text
Series

Precision Medicine in Cancers and Non-Communicable Diseases / by Barh, Debmalya

Table of Contents: “…Ch_2: Circulating tumor cells and circulating tumor DNA in precision medicine --…”
Click here to view.

Inborn errors of ketone body metabolism

Table of Contents: “…Contents: Ketone body metabolism -- Diagnostic approach -- Defects in ketogenesis -- Defects in ketone body utilization (succinyl-CoA:3-ketoacid CoA transferase deficiency, mitochondrial acetoacetyl-CoA thiolase deficiency) -- Molecular basis of mitochondrial acetoacetyl-CoA thiolase deficiency (protein and DNA levels).…”
Get full text
Series

MRD driven multiple myeloma treatment next step forward /

Table of Contents: “…Contents: MRD testing in Multiple Myeloma (MM) -- Selected treatment responses in newly diagnosed patients -- MRD negativity and disease progression -- Determination trial (IFM 2009) -- MSKCC treatment paradigm -- Developing DNA based assays -- Recurrent MM -- MRD positivity -- Different drug combinations -- MRD testing -- Future directions.…”
Get full text
Series

Gene profiling in breast cancer

Table of Contents: “…Contents: DNA microarrays and PCR can provide information about the biology of breast cancer, prediction of response and prognosis -- A molecular taxonomy of breast cancer has been proposed based on gene profiling -- Prediction of response is still inaccurate and further studies should be performed -- Several prognostic profiles have proved advantage over classical prognostic factors -- They could be used in the near future to select patients for adjuvant chemotherapy in breast cancer.…”
Get full text
Series