Search Results - "stem cell"

Stem cells immortality or healthy old age? /

Table of Contents: “…Contents: What is a stem cell? -- Properties of stem cells -- Adult and embryonic stem cells -- What is immortality? …”
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Stem cell memory

Table of Contents: “…Contents: Defining stem cell memory -- Deterministic asymmetric self-renewal evidence -- Two classes of adult stem cell memory -- The genetic fidelity problem -- Chromosome segregation vs. co-segregation -- Asymmetric self-renewal models -- Biochemical control of asymmetric self-renewal -- Potential molecular elements -- ASRA gene signature discovery -- Properties of H2A.Z.…”
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Hematopoietic stem cells the power of clonal assays /

Table of Contents: “…Contents: The haematopoietic process -- Spleen colony assay -- Colony forming assay -- Competition repopulation assay -- Haematopoietic stem cell subtypes and leukemia -- Index sorting experiments and the identification of a molecular overlap -- Assessing somatic mutations within HSC colonies -- Recapture experiments -- Inferring HSC population size.…”
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Cancer stem cells

Table of Contents: “…Contents: Introduction to normal and cancer stem cell (CSCs) -- Leukemia CSCs -- Solid tumor CSCs -- Possible origin of CSCs -- Functional assays for CSCs -- Conversion of non-CSCs to CSCs -- Epithelial-mesenchymal transition (EMT) -- CSC plasticity and heterogeneity -- Signaling and epigenetic regulators of CSCs -- CSC niche -- Role of CSCs in therapeutic resistance -- Strategies for targeting CSCs.…”
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Stem cells from the early embryo

Table of Contents: “…Contents: Stem cells from the early mammalian embryo -- Mouse embryonic development -- Blastocyst reconstitution experiments -- Lineage specific transcription factors -- Lineage specific stem cell lines.…”
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Stem cells from adipose tissue

Table of Contents: “…Contents: Adipose Tissue Histology -- Adipose Tissue as a BioResource -- Adipose-derived cells: Characterization -- Cell Isolation Variables -- In Vivo Cell Location -- Unresolved Issues, Questions and Controversy -- How Should We Study Stem Cells? -- Self-assembling, 3-dimensional Spheres in Suspension Culture: An In Vitro Niche Model -- Advantages of 3-D Spheroid ASC Culture -- Translation of Adipose-derived Cell Therapies -- Commercialization.…”
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Hematopoietic stem cells and progenitor cells, their role in normal blood formation part 1 of 2 /

Table of Contents: “…Contents: Definition of stem cells -- Hematopoietic stem cell -- Hematopoietic and progenitor cell lineages (Weissman model) -- Hematopoiesis: alternative model -- Hematopoiesis from multipotent stem cell -- Multi-potent hematopoietic stem cell -- Cluster of differentiation (CD) & other markers to identify LT-HSC and ST-HSC, and multipotent progenitor cells (MMPs) -- Kinetics of hematopoiesis -- Stroma cells.…”
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Stem cells derived from amniotic fluid and placenta

Table of Contents: “…Contents: Introduction to the amniotic fluid and placenta -- Collecting stem cells from the amniotic fluid or placenta -- Cell markers in amniotic fluid or placenta derived stem cells -- Amniotic fluid or placenta derived stem cells are able to form embryoid bodies -- Uses of amniotic fluid or placenta derived stem cells: Immunomodulation -- Uses of amniotic fluid or placenta derived stem cells: Regenerative medicine -- Amniotic fluid or placenta derived stem cells can be differentiated into a variety of cell types -- Amniotic fluid stems cells in the kidney -- Necrotizing enterocolitis; a model and treatment with amniotic fluid stems cells -- Clinical uses of amniotic fluid or placenta derived stem cells.…”
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Intestinal stem cell-mediated repair in Drosophila part 1 of 2 /

Table of Contents: “…Contents: The adult Drosophila midgut contains tissue specific intestinal stem cells (ISCs) -- ISCs are the only dividing cells in the midgut and are responsible for maintaining midgut homeostasis and regeneration -- The ISC division gives rise to a renewed stem cell and an enteroblast, which can differentiate into secretory enteroendocrine cells or absorptive enterocytes -- Intrinsic factors such as Tuberous Sclerosis Complex and Myc coordinate the growth and division of ISCs -- Extrinsic factors such as Epidermal Growth Factor from surrounding cells and the interaction with basement membrane also regulate the rate of ISC division -- Insulin secreted from CNS function as a long-range growth factor to control ISC activity and therefore intestinal tissue homeostasis.…”
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Intestinal stem cell-mediated repair in Drosophila Part 2 of 2 /

Table of Contents: “…Contents: The adult Drosophila midgut contains tissue specific intestinal stem cells (ISCs) -- ISCs are the only dividing cells in the midgut and are responsible for maintaining midgut homeostasis and regeneration -- The ISC division gives rise to a renewed stem cell and an enteroblast, which can differentiate into secretory enteroendocrine cells or absorptive enterocytes -- Intrinsic factors such as Tuberous Sclerosis Complex and Myc coordinate the growth and division of ISCs -- Extrinsic factors such as Epidermal Growth Factor from surrounding cells and the interaction with basement membrane also regulate the rate of ISC division -- Insulin secreted from CNS function as a long-range growth factor to control ISC activity and therefore intestinal tissue homeostasis.…”
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Gene expression analysis of pluripotent stem cells

Table of Contents: “…Contents: Pluripotent stem cells and gene expression analysis -- Plutipotent Stem Cells -- iPSC from various genetic backgrounds using different reprogramming methods and culture conditions -- Need for better standardization methods and markers to confirm cell state -- Gene expression analysis to identify new biomarkers and to confirm cell type based on expression pattern.…”
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Role of polycomb proteins in gene transcription, stem cell and human diseases

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Hematopoietic stem cells and progenitor cells, their role in normal blood formation part 2 of 2 /

Table of Contents: “…Contents: Granulopoiesis -- Granulocyte-colony stimulating factor (G-CSF) -- Erythropoiesis -- Erythropoietin -- Thrombopoiesis -- Thrombopoietin -- Hematopoietic stem cell expansion: challenges and opportunities -- Telomerase (TERT+TR) expression & telomere length in long-term expansion cultures of umbilical cord blood CD 34+ cells -- Self-renewal probability of human hematopoietic stem cells is age dependent -- Hematopoietic stem cell expansion: challenges and opportunities -- The bone marrow sinusoidal vascular network -- Bone marrow stem cells evolve into various cells -- Perivascular homing and bone marrow retention of hematopoietic stem cells -- role of osteoblasts relative to SECs in stem cell homeostasis.…”
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Legacy of Drosophila genetics female germline stem cells /

Table of Contents: “…Contents: Lineage tracing -- Stem cell niches -- Germline stem cell niche in ovary -- Germline stem cell niche in testis – Dedifferentiation -- Stem cell signaling back to the niche -- Intestinal stem cells -- Stem cell chromatin.…”
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Stem and progenitor cells from peripheral blood

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Human hepatocyte isolation for clinical transplantation

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Genetics of tumor metastasis part 2 of 2 /

Table of Contents: “…Contents: Re-examining the stem-cell tumor model -- Interconvertibility between non-stem cells and stem cells -- The key for generating cancer stem cells (CSCs) from non-cancer stem cells -- Filopodium-like structures (FLPs) in metastatic cancer -- Mechanistic link between epithelial/mesenchymal transition (EMT) & the CSC state.…”
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