Search Results - "DNA"

DNA methylation

Table of Contents: “…Contents: Roles of DNA methylation -- Evolution of eukaryotic DNA methyltransferases -- Mechanism of action of DNA methyltransferases -- Specific loci targeting -- Histone modification -- Small interfering RNA.…”
Get full text
Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)

DNA methylation

Table of Contents: “…Contents: DNA methylation as an epigenetic mark -- location and patterns of methylated and nonmethylated CpG sites in the vertebrate genome -- factors determining DNA methylation patterns -- association of DNA methylation with stable gene silencing, e.g. methylation of CpG islands on the inactive X-chromosome, ensures long term repression of associated genes -- recruitment of corepressors that impose a silent chromatin structure -- repulsion of transcriptional activators by methyl-CpG leading to gene silencing -- the link between human disorders, including cancer, Rett Syndrome and ICF syndrome, and defects in the DNA methylation system.…”
Get full text
Series

The biochemistry of DNA and RNA part 2, biological function /

Subjects: “…DNA. 92065…”
Get full text

Genome-wide analyses of protein-DNA interactions

Table of Contents: “…Contents: Identifying genomic targets of DNA-binding factors -- Experimental methods -- Chromatin immunoprecipitation (ChIP) assay -- Probing microarrays -- ChIP-on-chip assays for comprehensive analysis -- Data interpretation and follow-up studies.…”
Get full text
Series

Gene structure, expression and regulation DNA structure and replication /

Table of Contents: “…Contents: DNA structure -- DNA replication process -- DNA replication is continuous just on one strand -- Initiation of replication occurs at origin (oriC) -- Elongation of replication -- DNA replication in humans -- The transcription process -- Initiation of transcription in eukaryotic cell -- Elongation of transcription and termination -- Maturation of RNA and splicing -- Additional post transcription modification.…”
Get full text
Series

Polycomb epigenetic mechanisms Part 2 of 2, methylation of DNA /

Table of Contents: “…Contents: PRC2 has an untargeted global function -- Chromatin immunoprecipitation (ChIP-seq) profiles -- H3K27 methylation -- The CBP/p300 acetylase complex -- The TRR complex (MLL3,4 in mammals) -- The DNA accessibility model -- How do PcG complexes repress? …”
Get full text
Series

Role of polycomb proteins in gene transcription, stem cell and human diseases

Subjects: Get full text
Series

Gene structure, expression and regulation translation and regulation of gene expression /

Subjects: “…DNA. 88312…”
Get full text
Series

Accessing and using ENCODE data

Subjects: Get full text
Series (Eukaryotic gene regulation)
Series (Introduction to human genetics)
Series (Using bioinformatics in the exploration of genetic diversity)
Series (Epigenetics, chromatin, transcription and cancer)

Polyadenylation of mRNA precursors mechanism, regulation and connections with other cellular processes /

Table of Contents: “…Contents: Polyadenylation of mRNA precursors -- The polyadenylation machinery -- A surprising complexity in PAP -- Hyperphosphorylation by MPF inhibits PAP activity -- Gld-2 in cytoplasmic polyadenylation in oocytes -- The polyadenylation machinery -- CPSF-73 is the 3' processing endonuclease -- CPSF-73 is absent in cytoplasmic polyadenylation -- CstF protein interactions -- Regulation of gene expression by alternative polyadenylation -- The C-terminal domain of RNAPII -- The CTD can stimulate 3' cleavage in vitro -- CPSF links transcription and 3' end formation -- RNA15 crosslinks to promoters -- Polyadenylation and links to other cellular processes -- CstF-50 -- BRCA1 -- BARD1 -- BRCA associated ring domain protein -- Why does BARD1 inhibit 3' processing? -- DNA damage inhibits 3' processing -- How does BARD1 inhibit 3' processing? …”
Get full text
Series

Histone dynamics, heritability and variants

Table of Contents: “…Contents: DNA is organized into chromatin which promotes compaction and brings about additional information -- The histone code hypothesis -- Chromatin dynamics and heritability -- Factors involved in chromatin dynamics -- Nucleosomes disruption and assembly following DNA replication fork passage -- General steps in chromatin assembly -- Histone chaperones and their possible roles (CAF-1, HIRA, ...) -- Histone H3 variants and chromatin assembly coupled or not with DNA synthesis -- Specific histone deposition pathways for each variant? …”
Get full text
Series (Epigenetics : concepts, theories, paradigms and mechanisms)
Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)

Mechanisms of transcription the eukaryotic pre-initiation complex /

“…Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.…”
Get full text
Series

Pre-mRNA splicing

“…Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.…”
Get full text
Series

Comparing transcriptomes of distant organisms the comparative ENCODE resource, part 1 of 2 /

“…Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.…”
Get full text
Series

Comparing transcriptomes of distant organisms models of gene expression, part 2 of 2 /

“…Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.…”
Get full text
Series

Transcriptional activation

Table of Contents: “…Contents: Transcription by RNA polymerase II -- Mediator complex -- Coactivator proteins -- Communication between DNA-binding proteins and general transcription machinery.…”
Get full text
Series

The basal transcription machinery for RNA polymerase II

Table of Contents: “…Contents: The basal transcription machinery for RNA polymerase II -- DNA transcription -- Basal or general transcription factors -- Chromatin modifications -- RNA polymerase II -- TFIID -- Mediator.…”
Get full text
Series