Search Results - "melanoma"
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- Melanoma 2
- Signal Transduction
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- Extracellular Signal-Regulated MAP Kinases 1
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RAS and RAF signaling in melanoma biology and therapies /
Published 2010Table of Contents: “…Contents: Melanoma -- BRAF and RAS mutated in approximately 70% of cases -- Mouse models of melanoma -- Oncogenic BRAF can be a founder mutation in melanoma -- Mouse models replicate human disease -- BRAF inhibitors induce paradoxical activation of CRAF and drive pathway activation -- Kinase-dead BRAF mimics this and potentiates RAS ooncogenesis -- BRAF inhibitors induce excellent responses in patients, but may induce mechanism-based side effects through CRAF.…”
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2
A novel cancer therapy to stimulate oncogenic ERK signalling
Published 2018Subjects: Get full text
Series
Electronic Video