Search Results - "proteomics"

The chloroplast proteome

Table of Contents: “…Contents: What is proteomics and what does it measure? -- Protein identification by mass spectrometry -- The problem of complex mixtures and protein identification -- Quantitative proteomics and stable isotope labeling -- Intact protein mass measurements and top-down proteomics.…”
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The chloroplast proteome

Table of Contents: “…Contents: What is proteomics and what does it measure? -- Protein identification by mass spectrometry -- The problem of complex mixtures and protein identification -- Quantitative proteomics and stable isotope labeling -- Intact protein mass measurements and top-down proteomics.…”
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Proteomic technologies and targets an overview /

Table of Contents: “…Contents: Introduction -- The relationship between genome and proteome -- Why should we analyse the proteome? -- Challenges in proteome analysis -- Dynamic range of the proteome -- Complexity of the proteome -- Spatiotemporal organisation -- Dynamic changes in protein concentrations and modifications -- Technologies for analysing the proteome -- Mass spectrometry -- Protein arrays -- Imaging -- Data analysis -- The applications of clinical proteomics -- Biomarkers -- Systems biology approaches.…”
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Proteomics in cardiovascular disease clinical considerations /

Table of Contents: “…Contents: Systems biology -- Definition of proteomics -- Proteomics: rationale and practical aspects -- Proteomics in cardiovascular pathophysiology -- Proteomics to detect biomarkers of cardiovascular disease -- Urinary proteomics using capillary electrophoresis / mass spectrometry -- Proteomics of coronary artery disease -- Proteomics of pre-eclampsia -- Proteomics of other cardiovascular diseases: stroke, heart failure, diabetic nephropathy.…”
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Proteomics in kidney disease clinical considerations /

Table of Contents: “…Contents: Proteomics for clinical use -- Available and applied single risk marker strategies in nephrology based on hypothesis driven biomarker search -- Open or unbiased multimarker approaches including plasma and urine proteomics -- Examples from different renal diseases -- Data from cross sectional and longitudinal studies -- Proteomics may provide insight into disease pathology -- Proteomics may provide risk stratification for clinical trials -- Example: intervention trial for type 2 diabetic subjects with high risk urinary proteomic pattern.…”
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Proteomics in cardiovascular disease clinical considerations /

Table of Contents: “…Contents: Systems biology -- Definition of proteomics -- Proteomics: rationale and practical aspects -- Proteomics in cardiovascular pathophysiology -- Proteomics to detect biomarkers of cardiovascular disease -- Urinary proteomics using capillary electrophoresis / mass spectrometry -- Proteomics of coronary artery disease -- Proteomics of pre-eclampsia -- Proteomics of other cardiovascular diseases: stroke, heart failure, diabetic nephropathy.…”
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Proteomics in kidney disease clinical considerations /

Table of Contents: “…Contents: Proteomics for clinical use -- Available and applied single risk marker strategies in nephrology based on hypothesis driven biomarker search -- Open or unbiased multimarker approaches including plasma and urine proteomics -- Examples from different renal diseases -- Data from cross sectional and longitudinal studies -- Proteomics may provide insight into disease pathology -- Proteomics may provide risk stratification for clinical trials -- Example: intervention trial for type 2 diabetic subjects with high risk urinary proteomic pattern.…”
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Series (Clinical proteomics)
Series (Kidney in health and disease)

Proteomic technologies and targets an overview /

Table of Contents: “…Contents: Introduction -- The relationship between genome and proteome -- Why should we analyse the proteome? -- Challenges in proteome analysis -- Dynamic range of the proteome -- Complexity of the proteome -- Spatiotemporal organisation -- Dynamic changes in protein concentrations and modifications -- Technologies for analysing the proteome -- Mass spectrometry -- Protein arrays -- Imaging -- Data analysis -- The applications of clinical proteomics -- Biomarkers -- Systems biology approaches.…”
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Proteomics in cardiovascular disease clinical considerations /

Table of Contents: “…Contents: Systems biology -- Definition of proteomics -- Proteomics: rationale and practical aspects -- Proteomics in cardiovascular pathophysiology -- Proteomics to detect biomarkers of cardiovascular disease -- Urinary proteomics using capillary electrophoresis / mass spectrometry -- Proteomics of coronary artery disease -- Proteomics of pre-eclampsia -- Proteomics of other cardiovascular diseases: stroke, heart failure, diabetic nephropathy.…”
Get full text
Series

Proteomics in kidney disease clinical considerations /

Table of Contents: “…Contents: Proteomics for clinical use -- Available and applied single risk marker strategies in nephrology based on hypothesis driven biomarker search -- Open or unbiased multimarker approaches including plasma and urine proteomics -- Examples from different renal diseases -- Data from cross sectional and longitudinal studies -- Proteomics may provide insight into disease pathology -- Proteomics may provide risk stratification for clinical trials -- Example: intervention trial for type 2 diabetic subjects with high risk urinary proteomic pattern.…”
Get full text
Series (Clinical proteomics)
Series (Kidney in health and disease)

Proteomic technologies and targets an overview /

Table of Contents: “…Contents: Introduction -- The relationship between genome and proteome -- Why should we analyse the proteome? -- Challenges in proteome analysis -- Dynamic range of the proteome -- Complexity of the proteome -- Spatiotemporal organisation -- Dynamic changes in protein concentrations and modifications -- Technologies for analysing the proteome -- Mass spectrometry -- Protein arrays -- Imaging -- Data analysis -- The applications of clinical proteomics -- Biomarkers -- Systems biology approaches.…”
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Urinary proteomics in kidney and cardiovascular disease

Table of Contents: “…Contents: Omics technologies -- Technology platforms: (2DE-MS, LC-MS-MS, CE/MS) -- Clinical proteomics -- Precision as a function of no. of markers -- Human urinary LMW proteome database -- Requirements for biomarker selection -- How to identify valid proteomic biomarkers -- Effect size estimation and the number of samples -- Erroneous biomarkers -- Classification using different sizes of training sets -- Classification errors -- CKD biomarkers -- Biomarker validation -- Pathophysiological suggestions -- Selected urinary peptides and CKD staging -- Multicentric European PRIORITY trial -- Proteomics of coronary artery disease and of diabetic nephropathy.…”
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Series (Clinical proteomics)
Series (Kidney in health and disease)

Urinary proteomics in kidney and cardiovascular disease

Table of Contents: “…Contents: Omics technologies -- Technology platforms: (2DE-MS, LC-MS-MS, CE/MS) -- Clinical proteomics -- Precision as a function of no. of markers -- Human urinary LMW proteome database -- Requirements for biomarker selection -- How to identify valid proteomic biomarkers -- Effect size estimation and the number of samples -- Erroneous biomarkers -- Classification using different sizes of training sets -- Classification errors -- CKD biomarkers -- Biomarker validation -- Pathophysiological suggestions -- Selected urinary peptides and CKD staging -- Multicentric European PRIORITY trial -- Proteomics of coronary artery disease and of diabetic nephropathy.…”
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Series (Clinical proteomics)
Series (Kidney in health and disease)

Urinary proteomics in kidney and cardiovascular disease

Table of Contents: “…Contents: Omics technologies -- Technology platforms: (2DE-MS, LC-MS-MS, CE/MS) -- Clinical proteomics -- Precision as a function of no. of markers -- Human urinary LMW proteome database -- Requirements for biomarker selection -- How to identify valid proteomic biomarkers -- Effect size estimation and the number of samples -- Erroneous biomarkers -- Classification using different sizes of training sets -- Classification errors -- CKD biomarkers -- Biomarker validation -- Pathophysiological suggestions -- Selected urinary peptides and CKD staging -- Multicentric European PRIORITY trial -- Proteomics of coronary artery disease and of diabetic nephropathy.…”
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Series (Clinical proteomics)
Series (Kidney in health and disease)

Designing proteins with life sustaining activities part 1 of 2 /

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Designing proteins with life sustaining activities part 2 of 2 /

Table of Contents: “…Contents: Novel designed proteins: mechanism of action -- Function rescue experiments using novel proteins -- Evolving novel proteins (generalists vs. specialists) -- Towards artificial proteomes capable of sustaining life.…”
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Designing proteins with life sustaining activities part 1 of 2 /

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Designing proteins with life sustaining activities part 2 of 2 /

Table of Contents: “…Contents: Novel designed proteins: mechanism of action -- Function rescue experiments using novel proteins -- Evolving novel proteins (generalists vs. specialists) -- Towards artificial proteomes capable of sustaining life.…”
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Designing proteins with life sustaining activities part 1 of 2 /

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Designing proteins with life sustaining activities part 2 of 2 /

Table of Contents: “…Contents: Novel designed proteins: mechanism of action -- Function rescue experiments using novel proteins -- Evolving novel proteins (generalists vs. specialists) -- Towards artificial proteomes capable of sustaining life.…”
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