Search Results - "Huntington's disease"
Suggested Topics within your search.
Suggested Topics within your search.
- Neurodegenerative Diseases
- Huntington Disease 5
- Degeneration 4
- Huntington's disease 4
- Nervous system 4
- genetics 3
- pathology 3
- therapy 3
- Protein Conformation 2
- Protein Folding 2
- Trinucleotide Repeat Expansion 2
- Amyotrophic Lateral Sclerosis 1
- C9orf72 Protein 1
- Cellular therapy 1
- Chorea 1
- Diseases 1
- Dopaminergic Neurons 1
- Fragile X Syndrome 1
- Friedreich Ataxia 1
- Frontotemporal Dementia 1
- Gain of Function Mutation 1
- Genetic aspects 1
- Genetic disorders 1
- HSP40 Heat-Shock Proteins 1
- HTT protein, human 1
- Human Genetics 1
- Huntingtin Protein 1
- Microsatellite Repeats 1
- Mitochondria 1
- Mitochondrial Diseases 1
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Huntington's disease
Published 2021Table of Contents: “…Contents: Clinical features of Huntington's Disease -- Basic pathogenic mechanisms and pathology -- Current drug therapies -- New disease modifying therapies -- Neural transplants.…”
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Series
Electronic Video -
2
The molecular biology of Huntington's disease
Published 2020Subjects: “…Huntington's disease. 90221…”
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Series
Electronic Video -
3
Huntington's disease and HD-like disorders
Published 2014Table of Contents: “…Contents: Huntington's disease -- Huntington's disease like disorders -- Chorea -- Anticipation -- Pathobiology of Huntington's disease -- Huntingtin protein misfolding -- Aggregation -- Ubiquitous expression including in peripheral tissues -- Juvenile Huntington's disease/Westphal variant -- Psychiatric, behavioural and cognitive symptomatology -- HD phenocopies -- C9Orf72 and SCA17.…”
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Electronic Video -
4
Cell replacement therapy for neurodegenerative diseases
Published 2022Table of Contents: “…Contents: Parkinson's Disease and therapies available -- Preclinical data supporting cell therapies for Parkinson's -- Clinical data on fetal transplant trials in Parkinson's -- Development of stem cell-derived dopamine neurons -- Huntington's Disease and therapies available -- Preclinical data supporting cell therapies for Huntington's -- Clinical data on fetal transplant trials in Huntington's -- Development of stem cell-derived medium spiny neurons.…”
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Electronic Video -
5
Microsatellite and trinucleotide repeat expansion diseases
Published 2020Table of Contents: “…Contents: Mendelian neurodegenerative diseases are caused by repeat expansions -- The mutation can result in gain-of-function or loss-of-function -- Fragile X syndrome -- Myotonic dystrophy -- Huntington's disease -- Friedrich's ataxia -- C9orf72.…”
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Electronic Video -
6
Roles for Hsp40 molecular chaperones in protein misfolding disease
Published 2012Table of Contents: “…Contents: Protein aggregation in conformational disease -- The Hsp40 system -- The Hsp70 system -- Small oligomers, prion, yeast, Huntington's disease and protein triage -- Mechanisms for proteotoxicity -- Mechanisms for amyloid disease.…”
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Electronic Video -
7
Neuropathology of neurodegenerative disorders
Published 2007Table of Contents: “…Contents: Current neuropathological diagnostic criteria for neurodegenerative disorders -- Major macroscopic and microscopic features -- Pattern and extent of brain atrophy -- Alzheimer's disease -- Lewy body diseases -- Frontotemporal dementia -- Other tauopathies -- Huntington's disease -- Motor Neurone Disease.…”
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8
Mitochondrial disorders and neurodegeneration
Published 2007Table of Contents: “…Contents: Spectrum of mitochondrial diseases -- Mitochondrial metabolic pathway -- MtDNA mutations and disease -- Pathological features -- MELAS -- Genetic epidemiology of mtDNA mutations -- Structural components of respiratory chain complexes -- Mitochondrial DNA metabolism -- Mitochondrial proteins and oxidative phosphorylation -- Fatal mtDNA depletion syndrome -- POLG mutations -- Environmental influences on PD causation -- PARK genes -- Huntington's disease and mtDNA mutations -- Genetic basis of Friedreich's ataxia -- Mitochondrial toxins.…”
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Series (Mitochondrial biogenesis)
Series (Neurodegenerative diseases)
Electronic Video -
9
Protein aggregation, metals and oxidative stress in neurodegenerative diseases
Published 2007Table of Contents: “…Contents: Introduction to protein conformational brain diseases -- Alzheimer's disease, A-beta and tau -- A-beta oligomers and toxicity -- A-beta generates hydrogen peroxide -- Results from experiments using electron spin resonance spectroscopy -- Parkinson's disease -- Generation of hydrogen peroxide from alpha synuclein, toxic fragments of the prion protein and the familial British dementia peptide -- Early oligomers appear to generate hydrogen peroxide -- Huntington's disease -- Protein aggregates could be protective -- Potential common toxic pathway for these brain diseases.…”
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Electronic Video