Search Results - "proteins"

G proteins and GPCRs in cancer

Table of Contents: “…Contents: G proteins and GPCRs as oncogenes -- G proteins and GPCRs in tumorigenesis -- GPCR signalling -- GPCRs and metastasis -- GPCRs and tumor-induced angiogenesis -- GPCR targeting and immunotherapies.…”
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G proteins and GPCRs in cancer

Table of Contents: “…Contents: G proteins and GPCRs as oncogenes -- G proteins and GPCRs in tumorigenesis -- GPCR signalling -- GPCRs and metastasis -- GPCRs and tumor-induced angiogenesis -- GPCR targeting and immunotherapies.…”
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Role of polycomb proteins in gene transcription, stem cell and human diseases

Table of Contents: “…Contents: Chromatin structure -- Histone modification and regulation of methylation -- Polycomb complexes (gene silencing, recruitement & displacement of proteins, protein levels in embryoid bodies, binding regulation) -- PcG genes and human cancers -- Variations of Polycomb Repressive Complexes and their associations with polycomb proteins -- CBX family of proteins -- The Polycomb-like gene family.…”
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Role of polycomb proteins in gene transcription, stem cell and human diseases

Table of Contents: “…Contents: Chromatin structure -- Histone modification and regulation of methylation -- Polycomb complexes (gene silencing, recruitement & displacement of proteins, protein levels in embryoid bodies, binding regulation) -- PcG genes and human cancers -- Variations of Polycomb Repressive Complexes and their associations with polycomb proteins -- CBX family of proteins -- The Polycomb-like gene family.…”
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Role of polycomb proteins in gene transcription, stem cell and human diseases

Table of Contents: “…Contents: Chromatin structure -- Histone modification and regulation of methylation -- Polycomb complexes (gene silencing, recruitement & displacement of proteins, protein levels in embryoid bodies, binding regulation) -- PcG genes and human cancers -- Variations of Polycomb Repressive Complexes and their associations with polycomb proteins -- CBX family of proteins -- The Polycomb-like gene family.…”
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Three decades of protein phosphorylation and cancer the identification and characterization of the src gene product /

Table of Contents: “…Contents: The avian sarcoma virus genome and its products -- Cellular responses to the viral oncoprotein, Src -- The search for the ASV src gene product -- The RNA genome of avian sarcoma virus -- Searching for Src a function -- Impact of Src protein identification and characterization.…”
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Three decades of protein phosphorylation and cancer the identification and characterization of the src gene product /

Table of Contents: “…Contents: The avian sarcoma virus genome and its products -- Cellular responses to the viral oncoprotein, Src -- The search for the ASV src gene product -- The RNA genome of avian sarcoma virus -- Searching for Src a function -- Impact of Src protein identification and characterization.…”
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Three decades of protein phosphorylation and cancer the identification and characterization of the src gene product /

Table of Contents: “…Contents: The avian sarcoma virus genome and its products -- Cellular responses to the viral oncoprotein, Src -- The search for the ASV src gene product -- The RNA genome of avian sarcoma virus -- Searching for Src a function -- Impact of Src protein identification and characterization.…”
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The functions of the Hsp70 system

Table of Contents: “…Contents: Early steps and problems in nascent protein folding -- Molecular chaperones prevent protein aggregation -- Heat shock protein (molecular chaperone) classes -- Hsp70: characteristics and mechanism of action -- Hsp70 function and cancer (prevention of apoptosis) -- Hsp70 function and viral replication (the polyomaviruses) -- Hsp70 function and protein conformational diseases (ERAD).…”
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The functions of the Hsp70 system

Table of Contents: “…Contents: Early steps and problems in nascent protein folding -- Molecular chaperones prevent protein aggregation -- Heat shock protein (molecular chaperone) classes -- Hsp70: characteristics and mechanism of action -- Hsp70 function and cancer (prevention of apoptosis) -- Hsp70 function and viral replication (the polyomaviruses) -- Hsp70 function and protein conformational diseases (ERAD).…”
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The Myc transcription factor network

Table of Contents: “…Contents: Myc plays a broad role in cellular functions -- Deregulation of Myc is associated with many cancers -- Myc and Mxd proteins heterodimerize with Max, bind DNA, and activate or repress transcription through recruitment of co-regulator complexes that in turn influence chromatin modifications -- Myc family proteins are highly conserved and regulate cell growth by binding to many genes involved in translation and metabolism -- Myc also has functions unrelated to transcription -- Update talk: The MYC transcription factor network -- Update talk: Interactions of MYC with other cellular proteins -- Update talk: Topologically Associated Domains (TADs) -- Update talk: Transcriptional functions of MYC -- Update talk: Proximal MYC network -- Update talk: New approaches to inhibiting MYC activity.…”
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Series (Epigenetics, chromatin, transcription and cancer)

The Myc transcription factor network

Table of Contents: “…Contents: Myc plays a broad role in cellular functions -- Deregulation of Myc is associated with many cancers -- Myc and Mxd proteins heterodimerize with Max, bind DNA, and activate or repress transcription through recruitment of co-regulator complexes that in turn influence chromatin modifications -- Myc family proteins are highly conserved and regulate cell growth by binding to many genes involved in translation and metabolism -- Myc also has functions unrelated to transcription -- Update talk: The MYC transcription factor network -- Update talk: Interactions of MYC with other cellular proteins -- Update talk: Topologically Associated Domains (TADs) -- Update talk: Transcriptional functions of MYC -- Update talk: Proximal MYC network -- Update talk: New approaches to inhibiting MYC activity.…”
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Series (Cell division cycle)
Series (Epigenetics, chromatin, transcription and cancer)

LKB1 pathway and its role in cancer

Table of Contents: “…Contents: Mutations in LKB1 kinase cause Peutz Jeghers cancer syndrome -- LKB1-activation and effects -- LKB1/AMPK signaling pathway inhibits mTOR -- Evaluating the role of LKB1 in regulating PTEN-induced tumourigenesis -- AMPK-activators-mechanisms of action -- AMPK-activators delay tumor onset in mice -- Metformin as a useful drug in cancer prevention -- The LKB1:STRAD:MO25 complex -- Potential evolution of a pseudokinase -- LKB activation by STRAD and MO25 -- Location of LKB1 cancer mutations -- Activating protein kinases as a key challenge -- Analysis of the NUAK protein kinase -- Studying the role LKB1/NUAK1 signaling pathway in regulating cell adhesiveness and migration -- Modeling the novel LKB1.…”
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From CagA to CagA the metamorphoses of the Helicobacter pylori's cytotoxin-associated gene A into the cancer-associated gene A /

Subjects: “…cagA protein, Helicobacter pylori.…”
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LKB1 pathway and its role in cancer

Table of Contents: “…Contents: Mutations in LKB1 kinase cause Peutz Jeghers cancer syndrome -- LKB1-activation and effects -- LKB1/AMPK signaling pathway inhibits mTOR -- Evaluating the role of LKB1 in regulating PTEN-induced tumourigenesis -- AMPK-activators-mechanisms of action -- AMPK-activators delay tumor onset in mice -- Metformin as a useful drug in cancer prevention -- The LKB1:STRAD:MO25 complex -- Potential evolution of a pseudokinase -- LKB activation by STRAD and MO25 -- Location of LKB1 cancer mutations -- Activating protein kinases as a key challenge -- Analysis of the NUAK protein kinase -- Studying the role LKB1/NUAK1 signaling pathway in regulating cell adhesiveness and migration -- Modeling the novel LKB1.…”
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LKB1 pathway and its role in cancer

Table of Contents: “…Contents: Mutations in LKB1 kinase cause Peutz Jeghers cancer syndrome -- LKB1-activation and effects -- LKB1/AMPK signaling pathway inhibits mTOR -- Evaluating the role of LKB1 in regulating PTEN-induced tumourigenesis -- AMPK-activators-mechanisms of action -- AMPK-activators delay tumor onset in mice -- Metformin as a useful drug in cancer prevention -- The LKB1:STRAD:MO25 complex -- Potential evolution of a pseudokinase -- LKB activation by STRAD and MO25 -- Location of LKB1 cancer mutations -- Activating protein kinases as a key challenge -- Analysis of the NUAK protein kinase -- Studying the role LKB1/NUAK1 signaling pathway in regulating cell adhesiveness and migration -- Modeling the novel LKB1.…”
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Mitochondrial chaperonin Hsp60 locations, functions and pathology /

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From CagA to CagA the metamorphoses of the Helicobacter pylori's cytotoxin-associated gene A into the cancer-associated gene A /

Subjects: “…cagA protein, Helicobacter pylori. 109205…”
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From CagA to CagA the metamorphoses of the Helicobacter pylori's cytotoxin-associated gene A into the cancer-associated gene A /

Subjects: “…cagA protein, Helicobacter pylori. 109205…”
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CML genetic paradigm of targeted therapy, part 2 of 2 /

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