Search Results - "histone"
Suggested Topics within your search.
Suggested Topics within your search.
- Neoplasms
- genetics 5
- Epigenesis 4
- Epigenesis, Genetic 4
- Genetic aspects 4
- metabolism 4
- Cancer 3
- Chromatin 3
- Histone-Lysine N-Methyltransferase 3
- Histones 3
- Antineoplastic Agents 2
- Cell Transformation, Neoplastic 2
- Embryonic Stem Cells 2
- Methylation 2
- Stem Cells 2
- drug therapy 2
- pharmacology 2
- Antineoplastic agents 1
- Cancer cells 1
- Chromatin Assembly and Disassembly 1
- Chromosomal proteins 1
- DNA 1
- DNA Methylation 1
- Development 1
- Drug Discovery 1
- Gene Expression Regulation 1
- Genetic regulation 1
- Genetic transcription 1
- Histone Deacetylase Inhibitors 1
- Leukemia 1
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Epigenetic control by histone methylation
Published 2007Table of Contents: “…Contents: The diversity of covalent histone tail modifications for imparting epigenetic information -- Observations of robust histone modifications at silent chromatin regions -- The representation of repressive histone marks as indications of epigenetic plasticity in different cells -- Analysis of the profiles of normal and aberrant histone lysine methylation patterns, as they occur during the transition of an embryonic to a differentiated cell or in controlled self-renewal vs. pro-neoplastic or metastatic conditions -- Elucidation of these histone modification patterns for novel advances in stem cell research, nuclear reprogramming and cancer.…”
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Electronic Video -
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Epigenetics as a paradigm for cancer treatment chemically targeting the histone lysine methyltransferase EZH2 /
Published 2015Table of Contents: “…Contents: Cancer as an unmet medical need -- Epigenetics as a paradigm for treating cancer -- Histone lysine methyltransferase EZH2 as a target class example -- Development of EZH2 inhibitors.…”
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Electronic Video -
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Cancer-specific epigenetic alterations as investigated from a pharmaceutical perspective
Published 2021Subjects: Get full text
Electronic Video -
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Role of polycomb proteins in gene transcription, stem cell and human diseases
Published 2014Table of Contents: “…Contents: Chromatin structure -- Histone modification and regulation of methylation -- Polycomb complexes (gene silencing, recruitement & displacement of proteins, protein levels in embryoid bodies, binding regulation) -- PcG genes and human cancers -- Variations of Polycomb Repressive Complexes and their associations with polycomb proteins -- CBX family of proteins -- The Polycomb-like gene family.…”
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Series
Electronic Video