Search Results - "histone"
Suggested Topics within your search.
Suggested Topics within your search.
- Histones
- Epigenesis, Genetic 8
- genetics 8
- metabolism 8
- Chromatin 7
- Epigenesis 7
- Transcription, Genetic 6
- Gene Expression Regulation 5
- Genetic transcription 4
- physiology 4
- DNA 3
- DNA Methylation 3
- Genetic regulation 3
- Methylation 3
- Neoplasms 3
- Stem Cells 3
- Transcription Factors 3
- Cancer 2
- Chromatin Assembly and Disassembly 2
- Embryonic Stem Cells 2
- Genetic aspects 2
- Genetics 2
- Histone Code 2
- Histone-Lysine N-Methyltransferase 2
- Nucleosomes 2
- Polycomb-Group Proteins 2
- Protein Processing, Post-Translational 2
- Proteins 2
- cytology 2
- methods 2
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Epigenetic control by histone methylation
Published 2007Table of Contents: “…Contents: The diversity of covalent histone tail modifications for imparting epigenetic information -- Observations of robust histone modifications at silent chromatin regions -- The representation of repressive histone marks as indications of epigenetic plasticity in different cells -- Analysis of the profiles of normal and aberrant histone lysine methylation patterns, as they occur during the transition of an embryonic to a differentiated cell or in controlled self-renewal vs. pro-neoplastic or metastatic conditions -- Elucidation of these histone modification patterns for novel advances in stem cell research, nuclear reprogramming and cancer.…”
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Series
Electronic Video -
2
Histone dynamics, heritability and variants
Published 2022Table of Contents: “…Contents: DNA is organized into chromatin which promotes compaction and brings about additional information -- The histone code hypothesis -- Chromatin dynamics and heritability -- Factors involved in chromatin dynamics -- Nucleosomes disruption and assembly following DNA replication fork passage -- General steps in chromatin assembly -- Histone chaperones and their possible roles (CAF-1, HIRA, ...) -- Histone H3 variants and chromatin assembly coupled or not with DNA synthesis -- Specific histone deposition pathways for each variant? …”
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Series (Epigenetics : concepts, theories, paradigms and mechanisms)
Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)
Electronic Video -
3
Histone modifications and prospects for an epigenetic code
Published 2007Table of Contents: “…Contents: Enzyme-catalyzed modification of the N-terminal tail domains of core histones provides an array of marks across the nucleosome surface and a source of epigenetic information -- This information influences protein-protein interactions during short-term regulation of ongoing transcription and is a means of maintaining or modifying patterns of gene expression from one cell generation to the next -- Cellular memory -- Histone modifications may constitute a heritable epigenetic code that acts in concert with the genetic code as a long-term regulator of gene expression.…”
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Series
Electronic Video -
4
Epigenetics as a paradigm for cancer treatment chemically targeting the histone lysine methyltransferase EZH2 /
Published 2015Table of Contents: “…Contents: Cancer as an unmet medical need -- Epigenetics as a paradigm for treating cancer -- Histone lysine methyltransferase EZH2 as a target class example -- Development of EZH2 inhibitors.…”
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Electronic Video -
5
Introduction to epigenetics
Published 2020Table of Contents: “…Contents: Definition of epigenetics -- Three mechanisms; DNA methylation, histone modification, ncRNA -- Hypo and hyper DNA methylation and association with transcriptional state -- Mechanism of DNA methylation and enzymes responsible -- Examples of importance of DNA methytransferase enzymes -- Main types of histone modifications, concentrating on acetylation and methylation -- Mechanisms and enzymes for histone modifications -- Example of gene regulation by acetylation/deacetylation in Arabidopsis -- Non-coding RNA, using X-inactivation as an example -- The histone code.…”
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Electronic Video -
6
Chromatin architecture and alterations in the control of gene regulation
Published 2007Table of Contents: “…Contents: The chromatin environment -- Hierarchical organization of chromatin fibers within interphase chromosomes -- Milestone experiments that linked chromatin architecture and gene expression -- Proteins and processes that influence both chromatin fiber architecture and gene expression -- Core histone N-terminal tail domains -- Core histone sequence variants -- Linker histones -- Heterochromatin proteins -- Histone post-translational modifications -- The structurally dynamic nature of the genome in vivo and its relation to gene expression.…”
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Series
Electronic Video -
7
Polycomb epigenetic mechanisms Part 2 of 2, methylation of DNA /
Published 2017Subjects: Get full text
Series
Electronic Video -
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Role of polycomb proteins in gene transcription, stem cell and human diseases
Published 2014Table of Contents: “…Contents: Chromatin structure -- Histone modification and regulation of methylation -- Polycomb complexes (gene silencing, recruitement & displacement of proteins, protein levels in embryoid bodies, binding regulation) -- PcG genes and human cancers -- Variations of Polycomb Repressive Complexes and their associations with polycomb proteins -- CBX family of proteins -- The Polycomb-like gene family.…”
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Series
Electronic Video -
10
Comparing transcriptomes of distant organisms models of gene expression, part 2 of 2 /
Published 2017Table of Contents: “…Contents: Histone modification (HM) models relating gene expression to promoter activity -- Building a universal model for human, worm and fly -- Similarly constructed transcription factor (TF) binding models.…”
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Series
Electronic Video -
11