Search Results - "histone"
Suggested Topics within your search.
Suggested Topics within your search.
- Histone-Lysine N-Methyltransferase
- Neoplasms 3
- genetics 3
- metabolism 3
- Chromatin 2
- Epigenesis 2
- Epigenesis, Genetic 2
- Genetic aspects 2
- Histones 2
- Antineoplastic Agents 1
- Cancer 1
- Cancer cells 1
- Cell Transformation, Neoplastic 1
- Drug Discovery 1
- Embryonic Stem Cells 1
- Gene Expression Regulation 1
- Genetic regulation 1
- Leukemia 1
- Lysine 1
- Methylation 1
- Methyltransferases 1
- Molecular Targeted Therapy 1
- Myeloid-Lymphoid Leukemia Protein 1
- Nuclear Reprogramming 1
- Stem Cells 1
- Transcriptional Elongation Factors 1
- Treatment 1
- antagonists & inhibitors 1
- diagnosis 1
- drug effects 1
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Epigenetic control by histone methylation
Published 2007Table of Contents: “…Contents: The diversity of covalent histone tail modifications for imparting epigenetic information -- Observations of robust histone modifications at silent chromatin regions -- The representation of repressive histone marks as indications of epigenetic plasticity in different cells -- Analysis of the profiles of normal and aberrant histone lysine methylation patterns, as they occur during the transition of an embryonic to a differentiated cell or in controlled self-renewal vs. pro-neoplastic or metastatic conditions -- Elucidation of these histone modification patterns for novel advances in stem cell research, nuclear reprogramming and cancer.…”
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Series
Electronic Video -
2
Epigenetics as a paradigm for cancer treatment chemically targeting the histone lysine methyltransferase EZH2 /
Published 2015Table of Contents: “…Contents: Cancer as an unmet medical need -- Epigenetics as a paradigm for treating cancer -- Histone lysine methyltransferase EZH2 as a target class example -- Development of EZH2 inhibitors.…”
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Electronic Video -
3