Search Results - "DNA"

Human microsatellite and minisatellite DNA polymorphisms

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Inference on human history through DNA

Table of Contents: “…Contents: Human population structure -- Racial catalogs based on morphology -- Genetic variation within and between populations -- Genetic clustering of human populations -- Isolation by distance -- A recent demographic expansion from Africa -- Testing evolutionary hypotheses by coalescent simulation -- Ancient DNA.…”
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Ancient DNA and human evolutionary inference

Table of Contents: “…Contents: Patterns of genetic variation in Europe and the Neolithic -- Ancient DNA and anatomically modern humans (Challenges & Potential) -- The Neolithic transition in Europe (Scandinavia, Iberia and Eastern Europe).…”
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Techniques to infer admixture using genome-wide autosomal DNA part 1 of 2 /

Table of Contents: “…Contents: Introduction and illustrative simulations -- ADMIXTURE clustering software -- f3-statistics admixture detection software -- Autosomal DNA is used to date admixture -- ALDER/MALDER admixture detection and dating software.…”
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Techniques to infer admixture using genome-wide autosomal DNA part 2 of 2 /

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Gene copy number variation in human and primate evolution

Table of Contents: “…Contents: Primate evolution -- Human characteristics -- Molecular mechanisms underling genome evolution -- Gene duplication and evolutionary change -- Interhominoid cDNA array-based comparative genomic hybridization -- Major clusters of hominoid lineage -- Primate gene copy number changes -- Primate lineage-specific gene copy number variation -- Primate aCGH caveats.…”
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Gene-drives and active genetics introduction to gene-drives and their implications for health and society /

Table of Contents: “…Contents: Gene drives: overview -- CRISPR/Cas9 technology -- CRISPR/Cas9 DNA break repair -- Gene-drive elements spread rapidly in a population -- Active genetics: a new field -- Gene-drive systems -- Active genetics and drive effectors -- DNA repair mechanisms -- Mathematical modeling -- Social and ethical considerations.…”
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The future of CNVs sequence based resolution and links to human disease, part 1 of 2 /

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Series (Copy number variation)
Series (Biomarkers)

Linkage and sequence analysis in families

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Ethical issues in human population genetics

Table of Contents: “…Contents: The ethical issues in human genetics -- ELSI issues -- DNA in establishing identity -- DNA in unveiling the past -- DNA predicts the future -- Manipulation of DNA -- Ownership and control of DNA -- Deeper cultural changes -- Population genetics -- DNA in group history -- The Navajo people -- DNA in group stigma -- DNA in exploitation -- DNA and racism -- DNA and biological warfare -- The consent of a research population -- The NIH alternative for consent -- Control -- Confidentiality -- Return of information -- Benefit sharing.…”
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Statistical techniques in human population genetics

Table of Contents: “…Contents: Describe the biological & demographic processes that contribute to genetic diversity -- Describe statistical techniques that use observed DNA patterns to infer these past processes -- Illustrate the types of data used for inferring human history -- Highlight some key findings about human history derived through the use of these techniques.…”
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Genetics of Pakistani populations in an Asian and global context

Table of Contents: “…Contents: Population genetics -- Pakistan and south west Asia -- Human migrations -- DNA markers -- Alu repeats, SNPs and STRs -- Y chromosome, mitochondrial DNA and HLA markers unravel genetic relationships among populations in Asia and Pakistan.…”
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Human molecular evolution since the human-chimpanzee divergence

Table of Contents: “…Contents: Human-chimpanzee similarities -- Human-chimpanzee genomic comparison -- DNA duplication in human evolution -- DNA substitution in human evolution -- Modeling molecular evolution -- 2 goals of comparative genomics -- Identifying human accelerated regions (HARs).…”
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The peopling of the Americas new insights from genetic studies /

Table of Contents: “…-- Two different founding populations colonized the Americas -- Linguistic evidence -- Genetic background -- mtDNA lineages in native Americans -- mtDNA haplogroup frequencies in Siberia and the Americas -- Population history of Amerindian haplogroups -- Haplogroup X in North and Central America -- Prehistoric European migration to North America -- History and diversification of circumarctic peoples -- Ancient vs. modern population diversity -- Colonization of the Caribbean -- Y chromosome haplogroup frequencies in the Americas -- Y chromosome haplogroup frequencies in native Siberians -- Y chromosome SNP haplotype network -- Migration models based on Y chromosome data.…”
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Human Y-chromosome phylogenetics and phylogeography

Table of Contents: “…Contents: Framework of human genetic variation -- Locus specific forces vs. population level forces -- Y chromosome DNA sequence variation -- Genetic memory -- Phylogenetics, principles and characteristics -- Out of Africa -- Y chromosome phylogeography -- Recovering population histories.…”
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Genetic variation in North America

Table of Contents: “…Contents: Ethical & social implications of genetic research in indigenous communities -- A multidisciplinary approach to infer evolutionary history -- Genetic variation studies in Native Americans -- Ancient DNA research to bypass genomic effects of European colonization -- Non-indigenous admixture in Native Americans.…”
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Evolution how genes and their variation got here /

Table of Contents: “…Contents: Evolution by phenotype -- Basic factors of evolutionary change -- Mutation -- Genetic drift -- Natural selection -- Gene flow -- Current human variation -- Human global Y chromosome haplotype distribution -- Human global mtDNA haplotype distribution -- Selection for skin pigmentation and human evolution -- Genetic variation and selection for resistance to various forms of malaria -- Phenylketonuria (PKU) -- Deafness -- Breast cancer.…”
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Population genetics

Table of Contents: “…Contents: Studying human evolution using population genetics -- The history of population genetics -- Demographic models -- DNA datasets -- Example genealogies -- Calculating summary statistics (number of polymorphisms; average pairwise difference; Tajima's D) -- Inference -- Statistical significance -- Current work in population genetics -- Population genetics studies in Africa.…”
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Historical and geographical genetic variation Europe /

Table of Contents: “…Contents: Origin of modern Europeans -- Genetic tools -- Neanderthal vs. modern humans -- Complete mitochondrial DNA sequences: new data on the early events after the Out of Africa exit -- Paleolithic vs. …”
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History and geography of human genetic diversity I

Table of Contents: “…Contents: Four major factors of evolution: mutation, natural selection, drift, migration -- Role of demography in the quantitative study of evolution -- Drift: the Parma Valley study -- Equilibrium of migration and drift -- Founders' effect -- Reconstructing evolutionary history of a population -- Evidence of the importance of drift from molecular evolution -- Molecular evolution of proteins -- Trees with proteins and trees with DNA -- Phylogeographic analysis -- Microsatellites -- Graphic presentation of evolution data by principal components analysis.…”
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