Search Results - "yeast"

Spindle movement and checkpoint control during mitosis in yeast

Table of Contents: “…Contents: Cell cycle checkpoints for partitioning the genome -- Budding yeast as a model system for the study of genome distribution -- How nuclei are segregated in yeast -- Evidence for a spindle position checkpoint -- Model for checkpoint based on Tem1 -- Movie assay for checkpoint -- Search for upstream inputs -- Screen for checkpoint mutants -- Septins dual role in checkpoint -- Inputs to Lte1 -- Bud6 and microtubule capture -- Potential pathway for Bud6 -- Bud6 and microtubule-binding proteins -- Overexpression analysis -- Inhibition of Lte1 in the cold.…”
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Initiation of DNA replication

Table of Contents: “…Contents: Cell cycle control of DNA replication -- Yeast as a model eukaryote -- Control of S-phase entry in yeast -- Characterization of origins of DNA replication -- Modular structure of S. cerevisiae origins -- The budding yeast origin recognition complex (ORC) -- Structure of the ORC-Cdc6 complex -- Evolutionary comparison of ORC AAA+ subunits -- Proteins required for formation of the pre-Replication Complex (pre-RC) -- Cell cycle dependent association of yeast initiation proteins with chromatin -- ATP-dependent assembly of a pre-RC -- Cell cycle regulation of the pre-RC -- The chromosome cycle and establishment of pre-RCs -- Dynamic assembly and stability of ORC in human cells -- Commitment to S-phase and initiation -- Cdc45p is associated with chromatin in a cell cycle-dependent manner -- Temporal regulation of DNA replication -- Dynamics of pre-RC proteins in human cells differ from pre-RC proteins in yeast.…”
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Replication licensing

Table of Contents: “…Contents: Problems in ensuring complete genome replication -- Experiments revealing the existence of a replication licence -- The licensing reaction -- ORC, Cdc6, Cdt1 and Mcm2-7 -- Cell cycle regulation of licensing -- Pre-RC substrates in yeast -- Regulation of licensing in animal cells by Cdt1 degradation and geminin inhibition -- Is there a licensing checkpoint? …”
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