Search Results - "DNA"

DNA methylation

Table of Contents: “…Contents: Roles of DNA methylation -- Evolution of eukaryotic DNA methyltransferases -- Mechanism of action of DNA methyltransferases -- Specific loci targeting -- Histone modification -- Small interfering RNA.…”
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Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)

DNA methylation

Table of Contents: “…Contents: DNA methylation as an epigenetic mark -- location and patterns of methylated and nonmethylated CpG sites in the vertebrate genome -- factors determining DNA methylation patterns -- association of DNA methylation with stable gene silencing, e.g. methylation of CpG islands on the inactive X-chromosome, ensures long term repression of associated genes -- recruitment of corepressors that impose a silent chromatin structure -- repulsion of transcriptional activators by methyl-CpG leading to gene silencing -- the link between human disorders, including cancer, Rett Syndrome and ICF syndrome, and defects in the DNA methylation system.…”
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From DNA to proteins the multiple levels of regulation /

Table of Contents: “…Contents: General ideas behind DNA association with: histones, replication, transcription, splicing, RNA modifications, protein synthesis and death and global gene expression analysis.…”
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Genome-wide analyses of protein-DNA interactions

Table of Contents: “…Contents: Identifying genomic targets of DNA-binding factors -- Experimental methods -- Chromatin immunoprecipitation (ChIP) assay -- Probing microarrays -- ChIP-on-chip assays for comprehensive analysis -- Data interpretation and follow-up studies.…”
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Gene structure, expression and regulation DNA structure and replication /

Table of Contents: “…Contents: DNA structure -- DNA replication process -- DNA replication is continuous just on one strand -- Initiation of replication occurs at origin (oriC) -- Elongation of replication -- DNA replication in humans -- The transcription process -- Initiation of transcription in eukaryotic cell -- Elongation of transcription and termination -- Maturation of RNA and splicing -- Additional post transcription modification.…”
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Nucleosome dynamics and remodeling

Table of Contents: “…Contents: Chromatin composition -- Nucleosome structure and function -- Dynamic properties inherent to nucleosomes -- Invasion of nucleosomes by gene regulatory proteins -- DNA binding proteins and enzymes -- ATP dependent remodeling factors -- Nucleosome relocation.…”
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Elongation of protein synthesis structural basis of the peptide bond /

Subjects: “…DNA. 110136…”
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The principle of translation

Subjects: “…DNA. 110148…”
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Gene and protein microarrays tools for gene discovery and function /

Table of Contents: “…Contents: High-throughput methods to examine global gene expression -- Understanding interactions in a given cell, tissue and organism under normal and disease state conditions -- Application of high throughput methods used in genomics and proteomics -- Use of DNA and protein microarrays for gene discovery and function -- Background information and terminology used in genomics and proteomics -- How DNA and protein microarrays are carried out -- Predicted future direction of genomics and proteomics microarray technologies.…”
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Chromatin and transcription

Subjects: “…DNA. 110523…”
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The silent revolution an introduction to gene regulation by microRNAs /

Subjects: “…DNA. 109986…”
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mRNA capping

Subjects: “…DNA. 110034…”
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Chromatin architecture and alterations in the control of gene regulation

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Nuclear organization and gene expression

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Series (Epigenetics)
Series (From DNA to proteins)

Gene structure, expression and regulation translation and regulation of gene expression /

Subjects: “…DNA. 88312…”
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Introduction to epigenetics

Table of Contents: “…Contents: Definition of epigenetics -- Three mechanisms; DNA methylation, histone modification, ncRNA -- Hypo and hyper DNA methylation and association with transcriptional state -- Mechanism of DNA methylation and enzymes responsible -- Examples of importance of DNA methytransferase enzymes -- Main types of histone modifications, concentrating on acetylation and methylation -- Mechanisms and enzymes for histone modifications -- Example of gene regulation by acetylation/deacetylation in Arabidopsis -- Non-coding RNA, using X-inactivation as an example -- The histone code.…”
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Accessing and using ENCODE data

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Series (Eukaryotic gene regulation)
Series (Introduction to human genetics)
Series (Using bioinformatics in the exploration of genetic diversity)
Series (Epigenetics, chromatin, transcription and cancer)

Polyadenylation of mRNA precursors mechanism, regulation and connections with other cellular processes /

Table of Contents: “…Contents: Polyadenylation of mRNA precursors -- The polyadenylation machinery -- A surprising complexity in PAP -- Hyperphosphorylation by MPF inhibits PAP activity -- Gld-2 in cytoplasmic polyadenylation in oocytes -- The polyadenylation machinery -- CPSF-73 is the 3' processing endonuclease -- CPSF-73 is absent in cytoplasmic polyadenylation -- CstF protein interactions -- Regulation of gene expression by alternative polyadenylation -- The C-terminal domain of RNAPII -- The CTD can stimulate 3' cleavage in vitro -- CPSF links transcription and 3' end formation -- RNA15 crosslinks to promoters -- Polyadenylation and links to other cellular processes -- CstF-50 -- BRCA1 -- BARD1 -- BRCA associated ring domain protein -- Why does BARD1 inhibit 3' processing? -- DNA damage inhibits 3' processing -- How does BARD1 inhibit 3' processing? …”
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The transcription factor NF-Kappa B an evolutionarily conserved mediator of immune and inflammatory responses /

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Histone dynamics, heritability and variants

Table of Contents: “…Contents: DNA is organized into chromatin which promotes compaction and brings about additional information -- The histone code hypothesis -- Chromatin dynamics and heritability -- Factors involved in chromatin dynamics -- Nucleosomes disruption and assembly following DNA replication fork passage -- General steps in chromatin assembly -- Histone chaperones and their possible roles (CAF-1, HIRA, ...) -- Histone H3 variants and chromatin assembly coupled or not with DNA synthesis -- Specific histone deposition pathways for each variant? …”
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Series (Epigenetics : concepts, theories, paradigms and mechanisms)
Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)