Search Results - "epigenetics"

Epigenetics of lifestyle

Subjects: “…Epigenetics.…”
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Toxicology and epigenetics

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Epigenetics and pathology : exploring connections between genetic mechanisms and disease expression /

Table of Contents: “…1. Epigenetics of host-pathogen interactions : the road ahead and the road behind / Elena Gomez-Diaz, Mireia Jorda, Miguel Angel Peinado, and Ana Rivero -- 2. …”
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Epigenetics in agriculture

Table of Contents: “…Contents: Climate change: a global challenge for agriculture -- Crop plasticity and genotype x environment interactions -- Molecular basis of epigenetics -- Mapping epigenetic marks and epi-alleles -- Modulation of crop development and plasticity.…”
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Introduction to epigenetics

Table of Contents: “…Contents: Definition of epigenetics -- Three mechanisms; DNA methylation, histone modification, ncRNA -- Hypo and hyper DNA methylation and association with transcriptional state -- Mechanism of DNA methylation and enzymes responsible -- Examples of importance of DNA methytransferase enzymes -- Main types of histone modifications, concentrating on acetylation and methylation -- Mechanisms and enzymes for histone modifications -- Example of gene regulation by acetylation/deacetylation in Arabidopsis -- Non-coding RNA, using X-inactivation as an example -- The histone code.…”
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Epigenetics in age-related macular degeneration

Table of Contents: “…Contents: Epigenetics: terms and definitions -- Evidence for role of epigenetics in age-related macular degeneration (AMD) -- Future directions (potential for novel treatments for AMD).…”
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Epigenetic regulation of innate immunity

Subjects: “…Epigenetics. 107187…”
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Epigenetic pharmaceuticals used in the clinic

Table of Contents: “…Contents: Epigenetic drugs in chemotherapy -- Selecting patients for epigenetic therapy -- Side effects of epigenetic agents -- Unique therapeutic mechanisms of epigenetic treatments -- How is epigenetic therapy applied? …”
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Chromatin genes and disease

Table of Contents: “…Contents: Chromatin genes and disease -- Epigenetics: the phenotype reflects the pattern of gene expression -- The role of chromatin in epigenetic regulation -- Epigenetic factors and their role in gene expression -- Human diseases involving epigenetic factors.…”
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The dynamic interactions between cellular-molecular physiology and the environment part 2, The unicellular state as the level of selection - epigenetics /

Table of Contents: “…Contents: Select epigenetic "marks" are retained from generation to generation -- Inter- and transgenerational transmission of epigenetic marks is via germline cells -- approximately 97 per cent of human genetic diseases are likely caused by epigenetic inheritance -- Epigenetics allows for redefinition of terms in descriptive biology -- Epigenetic inheritance leads to the zygote as the primary level of selection -- The cellular-molecular approach to biology is predictive.…”
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Imprinting disorders associated with molecular changes on chromosome 11p15

Table of Contents: “…Contents: What is epigenetics? -- Epigenetic regulation forms the molecular basis for genomic imprinting -- What is genomic imprinting -- Imprinted genes in early development -- Genomic organization of imprinted genes -- Imprinting center -- Imprinted domain 1 on chromosome 11p15.5 -- Complexity of imprinted clusters -- Beckwith-Wiedemann syndrome (BWS) -- BWS: a complex, clinically heterogeneous disorder -- Molecular basis of BWS -- Etiology of the Beckwith-Wiedemann syndrome -- Molecular alterations associated with BWS -- Frequency of molecular alterations in BWS -- The risks to subfertile/ART treated parents -- Subfertility/assisted reproductive technologies (ART) -- BWS molecular defects -- Multiple phenotypes associated with somatic mosaicism for 11p15 UPD -- Somatic mosaicism -- Isolated hemihyperplasia -- High level constitutional UPD -- BWS molecular testing strategies -- Laboratory testing for BWS -- MS-MLPA -- Expected methylation results from MS-MLPA -- MLPA molecular testing for BWS -- Cancer risk & surveillance -- Prenatal testing options -- Current challenges in BWS molecular testing -- Frequency of CNVs according to methylation pattern -- Monozygotic twins and BWS -- Isolated hemihyperplasia -- Current challenges in chromosome 11p15 molecular testing -- Russell-Silver syndrome (RSS -- Chromosomal regions associated with RSS -- Targeted assays of multiple imprinted loci-BWS -- Different combinations of epigenetic alterations associated with variations in clinical phenotype -- Imprint deregulation causing disease in humans.…”
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Drug metabolism in liver disease

Table of Contents: “…Contents: Drug metabolism -- Liver disease and drug clearance -- Mechanistic explanations -- Intact hepatocyte hypothesis -- Sequential progressive model of liver disease -- Liver disease etiology -- Liver disease severity -- Epigenetics -- Biomarkers.…”
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