Search Results - "histone"
Suggested Topics within your search.
Suggested Topics within your search.
- Epigenesis
- Epigenesis, Genetic 11
- genetics 9
- metabolism 8
- Chromatin 7
- Histones 7
- Transcription, Genetic 6
- Chromatin Assembly and Disassembly 4
- DNA Methylation 4
- Gene Expression Regulation 4
- Genetic regulation 4
- Methylation 4
- Neoplasms 4
- physiology 4
- Cancer 3
- DNA 3
- Genetic aspects 3
- Genetic transcription 3
- Transcription Factors 3
- Antineoplastic Agents 2
- Embryonic Stem Cells 2
- Eukaryotic Cells 2
- Gene Expression Regulation, Developmental 2
- Gene Silencing 2
- Gene silencing 2
- Heterochromatin 2
- Histone Code 2
- Histone-Lysine N-Methyltransferase 2
- Polycomb-Group Proteins 2
- Protein Processing, Post-Translational 2
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1
Epigenetic control by histone methylation
Published 2007Table of Contents: “…Contents: The diversity of covalent histone tail modifications for imparting epigenetic information -- Observations of robust histone modifications at silent chromatin regions -- The representation of repressive histone marks as indications of epigenetic plasticity in different cells -- Analysis of the profiles of normal and aberrant histone lysine methylation patterns, as they occur during the transition of an embryonic to a differentiated cell or in controlled self-renewal vs. pro-neoplastic or metastatic conditions -- Elucidation of these histone modification patterns for novel advances in stem cell research, nuclear reprogramming and cancer.…”
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2
Histone dynamics, heritability and variants
Published 2022Table of Contents: “…Contents: DNA is organized into chromatin which promotes compaction and brings about additional information -- The histone code hypothesis -- Chromatin dynamics and heritability -- Factors involved in chromatin dynamics -- Nucleosomes disruption and assembly following DNA replication fork passage -- General steps in chromatin assembly -- Histone chaperones and their possible roles (CAF-1, HIRA, ...) -- Histone H3 variants and chromatin assembly coupled or not with DNA synthesis -- Specific histone deposition pathways for each variant? …”
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Series (Epigenetics : concepts, theories, paradigms and mechanisms)
Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)
Electronic Video -
3
Histone modifications and prospects for an epigenetic code
Published 2007Table of Contents: “…Contents: Enzyme-catalyzed modification of the N-terminal tail domains of core histones provides an array of marks across the nucleosome surface and a source of epigenetic information -- This information influences protein-protein interactions during short-term regulation of ongoing transcription and is a means of maintaining or modifying patterns of gene expression from one cell generation to the next -- Cellular memory -- Histone modifications may constitute a heritable epigenetic code that acts in concert with the genetic code as a long-term regulator of gene expression.…”
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4
Epigenetics as a paradigm for cancer treatment chemically targeting the histone lysine methyltransferase EZH2 /
Published 2015Table of Contents: “…Contents: Cancer as an unmet medical need -- Epigenetics as a paradigm for treating cancer -- Histone lysine methyltransferase EZH2 as a target class example -- Development of EZH2 inhibitors.…”
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Electronic Video -
5
Polycomb epigenetic mechanisms Part 2 of 2, methylation of DNA /
Published 2017Subjects: Get full text
Series
Electronic Video -
6
Cancer-specific epigenetic alterations as investigated from a pharmaceutical perspective
Published 2021Subjects: Get full text
Electronic Video -
7
DNA methylation
Published 2014Table of Contents: “…Contents: Roles of DNA methylation -- Evolution of eukaryotic DNA methyltransferases -- Mechanism of action of DNA methyltransferases -- Specific loci targeting -- Histone modification -- Small interfering RNA.…”
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Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)
Electronic Video -
8
Role of polycomb proteins in gene transcription, stem cell and human diseases
Published 2014Table of Contents: “…Contents: Chromatin structure -- Histone modification and regulation of methylation -- Polycomb complexes (gene silencing, recruitement & displacement of proteins, protein levels in embryoid bodies, binding regulation) -- PcG genes and human cancers -- Variations of Polycomb Repressive Complexes and their associations with polycomb proteins -- CBX family of proteins -- The Polycomb-like gene family.…”
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Skin epigenetics how chromatin regulators orchestrate skin functions /
Published 2014Table of Contents: “…-- Genes encoding keratinocyte-specific proteins -- Molecular signature of epidermal layers -- Levels of epigenetic regulation -- DNA methylation and hydroxymethylation -- DNA methylation influence on the epidermis -- Post-translational histone/covalent modifications -- Histone acetylation/de-acetylation -- Polycomb-repressive complex -- Polycomb and Trithorax play antagonistic roles -- ATP-dependent chromatin remodeling -- Non-coding RNA-dependent mechanisms -- Nucleus: storage, replication of genetic material -- Topological gene interactomes -- Morphogenesis of the epidermis -- Epidermal differentiation complex -- EDC and Lor relocation to nuclear interior -- p63 and Brg1 ablation results in retention of EDC -- Genome organizer AT-rich binding Satb1 protein -- Transcription factor and epigenetic mechanisms -- Future directions of epigenetic research.…”
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Series
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11
Heterochromatin, epigenetics and gene expression
Published 2014Table of Contents: “…Contents: Heterochromatin as a cytological phenomenon -- Heterochromatin and gene silencing -- Heterochromatin and DNA accessibility -- Histone modification and control of heterochromatin assembly -- Stability of epigenetic silencing by heterochromatin during development -- Heterochromatin and telomere stability.…”
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Series (Epigenetics, chromatin, transcription and cancer)
Series (Molecular genetics of human disease)
Electronic Video