Search Results - "epigenetics"

Epigenetics linking genotype and phenotype in development and evolution /

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Livestock epigenetics

Table of Contents: “…Epigenetics of mammalian gamete and embryo development / Nelida Rodriguez-Osorio, Sule Dogan, and Erdogan Memili -- Epigenetics of cloned pre-implantation embryos of domestic animals / Xiuchun Cindy Tian and Sadie L. …”
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Cytoplasmic epigenetics inheritance by cytoplasmic continuity /

“…Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.…”
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Skin epigenetics how chromatin regulators orchestrate skin functions /

Table of Contents: “…Contents: Skin structure, functions and development -- Molecular control of cell differentiation -- What is epigenetics? -- What controls variability of skin phenotypes? …”
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Epigenetics and inheritance

Table of Contents: “…Contents: Definition of epigenetics -- Epigenetics and stem cell biology -- Mechanisms of inheritable epigenetics -- Examples of the epigenetic code -- Genomic imprinting -- Imprinting as a paradigm for epigenetic gene regulation and inheritance -- Developmental Origins of Health and Disease (DOHaD) definition -- Dutch hunger winter as an example of DOHaD -- IVF as a potential example of DOHaD -- IVF technology and imprinting disorders.…”
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Epigenetic regulation and epigenomics

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Polycomb epigenetic mechanisms part 1 of 2, role of PcG complexes /

“…Polycomb epigenetic mechanisms. Part 1, role of PcG complexes…”
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Epigenetic biomarkers in cancer

Table of Contents: “…Contents: Epigenetics -- levels of control -- The patient cancer journey-multiple impact points -- Key translational areas for epigenetics -- DNA methylation as cancer biomarker -- DNA methylation analysis methods -- Epigenetic gene silencing in malignant cells -- CpG methylation and clinical outcome -- Causes of aberrant DNA methylation in cancer -- Stem cell targets -- EZH2 as a potential anti-cancer target -- Epigenetic modification as drug targets -- Epigenetic therapies -- DNA methylation versus platinum resistance -- Phase II trial of Decitabine & Carboplatin -- Effects of low doses of DNA-demethylation agents -- Epigenetic therapies challenges.…”
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Polycomb epigenetic mechanisms Part 2 of 2, methylation of DNA /

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Heterochromatin, epigenetics and gene expression

Table of Contents: “…Contents: Heterochromatin as a cytological phenomenon -- Heterochromatin and gene silencing -- Heterochromatin and DNA accessibility -- Histone modification and control of heterochromatin assembly -- Stability of epigenetic silencing by heterochromatin during development -- Heterochromatin and telomere stability.…”
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Series (Epigenetics, chromatin, transcription and cancer)
Series (Molecular genetics of human disease)

Epigenetic control by histone methylation

Table of Contents: “…Contents: The diversity of covalent histone tail modifications for imparting epigenetic information -- Observations of robust histone modifications at silent chromatin regions -- The representation of repressive histone marks as indications of epigenetic plasticity in different cells -- Analysis of the profiles of normal and aberrant histone lysine methylation patterns, as they occur during the transition of an embryonic to a differentiated cell or in controlled self-renewal vs. pro-neoplastic or metastatic conditions -- Elucidation of these histone modification patterns for novel advances in stem cell research, nuclear reprogramming and cancer.…”
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Histone modifications and prospects for an epigenetic code

Table of Contents: “…Contents: Enzyme-catalyzed modification of the N-terminal tail domains of core histones provides an array of marks across the nucleosome surface and a source of epigenetic information -- This information influences protein-protein interactions during short-term regulation of ongoing transcription and is a means of maintaining or modifying patterns of gene expression from one cell generation to the next -- Cellular memory -- Histone modifications may constitute a heritable epigenetic code that acts in concert with the genetic code as a long-term regulator of gene expression.…”
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Epigenetics as a paradigm for cancer treatment chemically targeting the histone lysine methyltransferase EZH2 /

Table of Contents: “…Contents: Cancer as an unmet medical need -- Epigenetics as a paradigm for treating cancer -- Histone lysine methyltransferase EZH2 as a target class example -- Development of EZH2 inhibitors.…”
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Nuclear cloning, stem cells and epigenetic reprogramming

“…Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.…”
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Cancer-specific epigenetic alterations as investigated from a pharmaceutical perspective

Table of Contents: “…Contents: Chromatin dysregulation in cancer -- Features of epigenetic information in cells -- Mutated chromatin regulatory factors as tumor drivers -- Therapeutic rationale for the use of epigenetic drugs in oncology -- First generation epigenetic drugs: DNMT and HDAC inhibitors -- Novel therapeutic discoveries in oncology -- Biomarkers for patient selection.…”
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Biomolecular therapeutics for human cancer

Table of Contents: “…(Publisher-supplied data) Section I: Epigenetics and Cell Cycle -- Epigenetic modulation of Cell Cycle: an overview? …”
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Maintaining the silenced state of master regulatory genes during development

Table of Contents: “…-- PRC1 in compaction and ubiquitylation -- Nucleosome dynamics -- Characteristics of the compaction domain -- Gene silencing by chromatin compaction -- The SIR complex and mating type silencing -- Structural rearrangements in NCP and BAH -- Folding events in Sir3 BAH/NCP complex -- The nucleosome as a silencing machinery -- Epigenetic memory.…”
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Role of polycomb proteins in gene transcription, stem cell and human diseases

“…Biomedical & life sciences collection. Epigenetics, chromatin, transcription and cancer.…”
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Genomic imprinting history and embryology /

“…Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.…”
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Gene silencing in budding yeast

Table of Contents: “…Contents: Gene silencing: an epigenetic phenomenon -- Chromatin remodeling: heterochromatin and euchromatin -- Silent chromatin in budding yeast: mating-type loci -- Silent information regulation: telomeric genes and Sir proteins.…”
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