Search Results - "vaccination"

Approaches to nonclinical vaccine development

Table of Contents: “…Contents: Brief history of vaccination -- How vaccines work -- The importance of vaccination -- Current regulatory guidelines for vaccines -- Considerations in the design of toxicity studies -- Routine toxicity studies for vaccines -- Nonclinical toxicity testing strategies.…”
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Challenges of accelerated vaccine development

Table of Contents: “…Contents: Vaccine development under normal circumstances -- Ebola: virus transmission, disease and outbreaks -- Ebola as a case-study for challenges of accelerated vaccine development -- Demonstrating safety, efficacy, and manufacturing consistency -- Challenges in cutting clinical development from 10+ to 5 years -- Vaccine acceleration can be achieved through good partnership.…”
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SARS-COV-2 vaccine current biological targets and considerations /

Table of Contents: “…Contents: Comparison of SARS-COV-2 with other coronavirus strains -- Targets for a SARS-COV-2 vaccine -- Other considerations once a vaccine has been developed.…”
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Vaccines and the fight against antimicrobial resistance 1

Table of Contents: “…Contents: An introduction to Antimicrobial Resistance (AMR) -- The emergence and spread of AMR -- The mechanism of action of vaccines -- The impact of vaccines on AMR -- Herd immunity -- Licensed vaccines and their ability to fight AMR -- H. influenzae type b polysaccharide conjugate vaccines -- Pneumococcal polysaccharide conjugate vaccines (PCVs) -- S. …”
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SARS-COV-2 vaccine development where are we now? /

Table of Contents: “…Contents: Vaccine development for SARS-COV-2: Current position -- Different types of potential vaccines against COVID-19 -- New technologies and their implications -- How past experience can support current research.…”
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Vaccines and the fight against antimicrobial resistance 2

Table of Contents: “…Contents: Vaccines in late-stage development with a potential to reduce AMR -- Vaccines in early-stage development with a potential to reduce AMR -- Global mobilization actions utilizing vaccines against AMR -- The Davos Declaration -- Barriers to maximizing licensed vaccine use in fighting AMR -- Efforts towards better utilization of vaccines against AMR.…”
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SARS-CoV-2 vaccine development

Table of Contents: “…Contents: Current efforts to develop a vaccine -- Possible strategies for vaccine development -- Possible seasonal variations in virus prevalence -- When could a viable vaccine be expected?.…”
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The development of SARS-CoV-2 vaccines

Table of Contents: “…Contents: Overview of three SARS-CoV-2 vaccines being developed -- Technologies being used -- Manufacturability -- Current stage of testing -- Next steps.…”
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Development of an intranasal vaccine for SARS-CoV-2

Table of Contents: “…Contents: General mechanism of action of DNA vaccines -- Adenoviral vectors for DNA delivery to host cells -- Advantages and limitations of intranasal vaccines -- Cellular, mucosal and antibody immunity in the context of SARS-2 -- Stability of AdCOVID at room temperature -- Earliest possible approval of AdCOVID -- How far and how fast can this vaccine then be deployed?…”
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SARS-COV-2 what we need to know and possible future therapies /

Table of Contents: “…Contents: SARS-COV-2 compared with other coronavirus strains -- How this comparison can help in containment, treatment, and vaccination -- Future considerations for vaccine development -- Other possible treatments for COVID-19.…”
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COVID-19 epidemiology and potential treatments follow up interview /

Table of Contents: “…-- "Infectious dose" or "number of viruses" versus "viral load" -- Recent clinical trial results for SARS-2 treatments and vaccines -- Current clinical trials in Europe and the US.…”
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The paediatric response to the SARS-COV-2 virus and what we can learn from it

Table of Contents: “…Contents: Current hypotheses on why children are less effected by COVID-19 than older individuals -- How this knowledge might benefit the treatment of older individuals -- Safety during related research -- The implications of this knowledge on vaccine development -- Future considerations for vaccine development.…”
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Elite controllers of HIV from discovery to future therapies /

Table of Contents: “…Contents: The discovery of HIV and elite controllers -- Initial research and clinical trials -- From HIV elite controllers to an HIV vaccine -- HIV structural constraints, structurally important regions and viral fitness -- Current and future challenges in HIV treatments.…”
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The evolutionary origin of SARS-CoV-2

Table of Contents: “…Contents: SARS-CoV-2: a product of zoonosis -- SARS-CoV-2 may have been mutating towards its current form for decades -- Evolutionary recombination events leading to SARS-CoV-2: bats & pangolins -- Genetic similarity and differences with other lethal coronaviruses: SARS-1 & MERS -- Phenotypic comparison of SARS-CoV-2 with other coronaviruses -- Genetic evidence debunking claims that SARS-CoV-2 is a deliberate human-engineered virus -- Probability, location and species of possible future emergence of zoonotic viruses -- Implications for SARS-CoV-2 vaccine development.…”
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COVID-19 epidemiology and variants new challenges and future of the pandemic /

Table of Contents: “…Contents: Emergence of new variants and their new evolutionarily advantageous traits -- Probability of the emergence of additional variants and a new strain of SARS-CoV-2 -- Potential immune escape mechanisms of a theoretical new SARS-CoV-2 strain -- What can governments and individuals do to reduce the probability of emergence of additional variants -- Efficacy shown to date by COVID-19 vaccines and their projected impact in controlling the pandemic -- Update on current COVID-19 treatments (including convalescent antibody therapy, Remdesivir and dexamethasone) and the importance of the time window for their administration.…”
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