Search Results - "amyloid"

Targeting Aß oligomers a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease /

Table of Contents: “…Contents: The oligomer cascade hypothesis for Alzheimer's Disease -- Why the oligomer hypothesis has largely supplanted the amyloid cascade hypothesis -- The role of AβOs in memory failure and the major facets of AD neuropathology -- Mechanisms by which AβOs instigate neurotoxicity -- Why AβOs accumulate in the first place -- How AβOs offer superb targets for novel AD diagnostics and disease-modifying therapeutics -- Beside its direct link to Alzheimer's disease, the discovery of toxic Aβ oligomers has provided a novel structural archetype for toxins germane to more than two dozen diseases of protein mis-folding, including Diabetes, Parkinson's, and prion diseases.…”
Get full text
Series

Targeting Aß oligomers a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease /

Table of Contents: “…Contents: The oligomer cascade hypothesis for Alzheimer's Disease -- Why the oligomer hypothesis has largely supplanted the amyloid cascade hypothesis -- The role of AβOs in memory failure and the major facets of AD neuropathology -- Mechanisms by which AβOs instigate neurotoxicity -- Why AβOs accumulate in the first place -- How AβOs offer superb targets for novel AD diagnostics and disease-modifying therapeutics -- Beside its direct link to Alzheimer's disease, the discovery of toxic Aβ oligomers has provided a novel structural archetype for toxins germane to more than two dozen diseases of protein mis-folding, including Diabetes, Parkinson's, and prion diseases.…”
Get full text
Series

Targeting Aß oligomers a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease /

Table of Contents: “…Contents: The oligomer cascade hypothesis for Alzheimer's Disease -- Why the oligomer hypothesis has largely supplanted the amyloid cascade hypothesis -- The role of AβOs in memory failure and the major facets of AD neuropathology -- Mechanisms by which AβOs instigate neurotoxicity -- Why AβOs accumulate in the first place -- How AβOs offer superb targets for novel AD diagnostics and disease-modifying therapeutics -- Beside its direct link to Alzheimer's disease, the discovery of toxic Aβ oligomers has provided a novel structural archetype for toxins germane to more than two dozen diseases of protein mis-folding, including Diabetes, Parkinson's, and prion diseases.…”
Get full text
Series

Update on fluid biomarkers for neurodegenerative diseases

Table of Contents: “…Contents: Fluid biomarker candidates for neurodegenerative disease -- Amyloid pathology -- CSF and plasma/serum NfL -- CSF Aβ42 in Alzheimer's disease and neuroinflammatory diseases -- Tau pathology in Alzheimer's disease -- Neurodegeneration -- CSF and plasma NfL as biomarkers for disease progression -- Drug treatment and NfL levels.…”
Get full text
Series (Biomarkers)
Series (Drug discovery and development in the neurosciences)
Series (Genetic basis of neurological disorders)

Update on fluid biomarkers for neurodegenerative diseases

Table of Contents: “…Contents: Fluid biomarker candidates for neurodegenerative disease -- Amyloid pathology -- CSF and plasma/serum NfL -- CSF Aβ42 in Alzheimer's disease and neuroinflammatory diseases -- Tau pathology in Alzheimer's disease -- Neurodegeneration -- CSF and plasma NfL as biomarkers for disease progression -- Drug treatment and NfL levels.…”
Get full text
Series (Biomarkers)
Series (Drug discovery and development in the neurosciences)
Series (Genetic basis of neurological disorders)

Molecular brain imaging (PET) in diseases with dementia

Table of Contents: “…Contents: Brain imaging with positron emission tomography (PET) for dementia diagnosis and research -- Cerebral glucose metabolism in mild cognitive impairment, Alzheimer's disease, dementia with Lewy bodies, frontotemporal dementia & depression -- Imaging of pathological markers (beta-amyloid and tau) in Alzheimer's disease -- Imaging of neurotransmitters and receptors, in the dopaminergic and cholinergic system -- Multiple systems profiling in dementia, Parkinson's and related motor disorders.…”
Get full text
Series (Periodic reports)
Series (Neurodegenerative diseases)

Molecular brain imaging (PET) in diseases with dementia

Table of Contents: “…Contents: Brain imaging with positron emission tomography (PET) for dementia diagnosis and research -- Cerebral glucose metabolism in mild cognitive impairment, Alzheimer's disease, dementia with Lewy bodies, frontotemporal dementia & depression -- Imaging of pathological markers (beta-amyloid and tau) in Alzheimer's disease -- Imaging of neurotransmitters and receptors, in the dopaminergic and cholinergic system -- Multiple systems profiling in dementia, Parkinson's and related motor disorders.…”
Get full text
Series (Periodic reports)
Series (Neurodegenerative diseases)

Alzheimer's diagnosis

Table of Contents: “…Quantitation of amyloid-[beta] oligomers in human body fluids for Alzheimer's disease early diagnosis or therapy monitoring? …”
An electronic book accessible through the World Wide Web; click to view