Search Results - "vaccination"

Vaccination

Table of Contents: “…Contents: The history of vaccination -- Mechanisms of vaccine action -- Types of vaccine -- Vaccine development process -- Vaccine platforms -- Vaccine adjuvants -- Pre-clinical and clinical testing of vaccine candidates.…”
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History of vaccines

Table of Contents: “…Contents: History of vaccines -- The impact of vaccination -- Variolation -- Pasteur and first real vaccines -- Inactivated vaccines at the end of the 19th Century -- Toxoids -- Attenuation by serial passage -- Viruses grown in cell culture -- Genetic engineering and recombinant vaccines -- Vaccines licensed since 2000 -- Cumulative number of vaccines developed.…”
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Vaccine manufacturing part 1 of 2 /

Table of Contents: “…Contents: The vaccine ecosystem -- How to make a vaccine (brief outline) -- Vaccine antigens -- Assessing vaccine quantities -- Technology & knowledge transfer -- Process development and scaling-up.…”
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Vaccine manufacturing part 2 of 2 /

Table of Contents: “…Contents: New vaccines & the need for up-to-date technology -- Considerations for manufacturing facilities -- Quality systems (The mechanism for regulatory compliance) -- Large scale, routine manufacturing -- Warehousing and distribution of vaccine product.…”
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Vaccine adjuvants part 2 of 2 /

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Dengue vaccine development l. Status /

Table of Contents: “…Contents: Scope of the dengue problem -- Assessing the need for a tetravalent vaccine -- In-depth look at current vaccines and their development status.…”
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Dengue vaccine development II. Problems to be solved /

Table of Contents: “…Contents: Projected availability of dengue vaccines -- Global dengue vaccine needs -- Vaccine delivery complexities -- How dengue vaccines can be improved.…”
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Malaria vaccine development part 1 of 2 /

Table of Contents: “…Contents: Distribution of malaria -- Burden of the disease and recent trends -- Malaria lifecycle and vaccine opportunities -- Biological evidence to support vaccine approaches.…”
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Vaccine preclinical studies part 1 of 2 /

Table of Contents: “…Contents: Introduction to vaccine research -- Goals of preclinical studies -- Preclinical safety for vaccines -- Drug vs. vaccine toxicology -- Basic vaccine toxicology -- Specialized toxicology studies.…”
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HIV vaccine development

Table of Contents: “…Contents: HIV virus biology and immune mechanisms -- Development of an HIV vaccine & accompanying difficulties -- New methods of vaccine development -- The ideal HIV vaccine -- HIV vaccine efficacy trials.…”
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Developing tuberculosis vaccines challenges and strategies, part 1 of 2 /

Table of Contents: “…Contents: M. tuberculosis exposure and infection -- Tuberculosis (TB) disease -- Antimicrobial Mtb resistance -- The BCG vaccine -- Challenges of the TB vaccine field -- Potential new & better vaccines -- The variety of Mtb antigens.…”
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Malaria vaccine development part 2 of 2 /

Table of Contents: “…Contents: Community vaccine development goals -- Increasing probability of success and reducing risk -- Progress against malaria vaccine technology roadmap goals.…”
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Developing tuberculosis vaccines challenges and strategies, part 2 of 2 /

Table of Contents: “…Contents: Diverse immunologic approaches to TB vaccines -- The human challenge model -- Antigen presentation & novel delivery platforms -- Diversification of routes and combinations -- Natural infection & improved animal models.…”
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Bacterial vaccines in development part 1 of 2 /

Table of Contents: “…Contents: New bacterial vaccines in clinical development -- Phases of vaccine development -- Principles of vaccine antigen discovery & validation -- Novel vaccines in development for Gram+ pathogens: C. difficile.…”
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Bacterial vaccines in development part 2 of 2 /

Table of Contents: “…Contents: Novel vaccines for Gram+ pathogens: S. aureus -- Novel vaccines for Gram- pathogens N. meningitides serogroup B.…”
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Vaccine preclinical studies part 2 of 2 /

Table of Contents: “…Contents: Vaccine pharmacology -- Vaccine immunogenicity -- Vaccine challenge-protection studies.…”
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Successes and failures with vaccines

Table of Contents: “…Contents: New strategies for vaccine development -- Influenza vaccines need improvement -- The microbiome influences rotavirus vaccine efficacy -- Vaccines against cytomegalovirus -- Vaccines against human papillomavirus and cervical cancer -- Insights from structural biology and the development of vaccines against respiratory syncytial virus -- Vaccines based on DNA and RNA.…”
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Future directions for vaccine discovery part 2 of 2 /

Table of Contents: “…Contents: Pre-erythrocytic vaccine for falciparum malaria -- Efficacy of RTS,S vaccine in humans -- Genomic and functional analysis of cloned human antibodies -- Improving acellular Pertussis vaccine (aP) -- New paradigm for vaccine development.…”
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Adenovirus vectors and vaccine responses

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Future directions for vaccine discovery part 1 of 2 /

Table of Contents: “…Contents: Vaccine R&D: too slow, high failure rate -- HIV vaccine goal: induce broadly neutralizing antibodies (bNAb) -- Mimicking nature to create bNAb -- Rules for inducing primary response with memory B cell breadth.…”
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