Search Results - "Huntington's disease"

Huntington's disease and HD-like disorders

Table of Contents: “…Contents: Huntington's disease -- Huntington's disease like disorders -- Chorea -- Anticipation -- Pathobiology of Huntington's disease -- Huntingtin protein misfolding -- Aggregation -- Ubiquitous expression including in peripheral tissues -- Juvenile Huntington's disease/Westphal variant -- Psychiatric, behavioural and cognitive symptomatology -- HD phenocopies -- C9Orf72 and SCA17.…”
Get full text
Series

Cell replacement therapy for neurodegenerative diseases

Table of Contents: “…Contents: Parkinson's Disease and therapies available -- Preclinical data supporting cell therapies for Parkinson's -- Clinical data on fetal transplant trials in Parkinson's -- Development of stem cell-derived dopamine neurons -- Huntington's Disease and therapies available -- Preclinical data supporting cell therapies for Huntington's -- Clinical data on fetal transplant trials in Huntington's -- Development of stem cell-derived medium spiny neurons.…”
Get full text

Microsatellite and trinucleotide repeat expansion diseases

Table of Contents: “…Contents: Mendelian neurodegenerative diseases are caused by repeat expansions -- The mutation can result in gain-of-function or loss-of-function -- Fragile X syndrome -- Myotonic dystrophy -- Huntington's disease -- Friedrich's ataxia -- C9orf72.…”
Get full text
Series

Roles for Hsp40 molecular chaperones in protein misfolding disease

Table of Contents: “…Contents: Protein aggregation in conformational disease -- The Hsp40 system -- The Hsp70 system -- Small oligomers, prion, yeast, Huntington's disease and protein triage -- Mechanisms for proteotoxicity -- Mechanisms for amyloid disease.…”
Get full text
Series

Metal-based neurodegeneration : from molecular mechanisms to therapeutic strategies / by Crichton, Robert R.

Table of Contents: “…Brain function, physiology, and the blood-brain barrier -- Role of metal ions in brain function, metal transport, storage, and homeostasis -- Immune system and neuroinflammation -- Oxidative stress in neurodegenerative diseases -- Aging and mild cognitive impairment, MCI -- Parkinson's disease -- Alzheimer's disease -- Huntington's disease and polyglutamine expansion neurodegenerative diseases -- Friedreich's ataxia and diseases associated with expansion of non-coding triplets -- Creutzfeldt-Jakob and other prion diseases -- Amyotropic lateral sclerosis -- Alcoholic brain damage -- Other neurological diseases -- Therapeutic strategies to combat the onset and progression of neurological diseases.…”
An electronic book accessible through the World Wide Web; click to view