Search Results - "epigenetics"

Epigenetics a historical overview / by Holliday, Robin, 1932-

Table of Contents: “…Contents: Introduction to epigenetics -- the leading pioneers in the field of epigenetics -- the basic features of development -- switching and heritability of gene activities -- DNA methylation -- epimutations -- differences between genetics and epigenetics -- genomic imprinting -- chromatin structure -- histone modifications -- the role of RNA in the epigenetic regulation of gene activity -- the bisulfite sequencing technique -- the epigenotype.…”
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Skin epigenetics how chromatin regulators orchestrate skin functions /

Table of Contents: “…Contents: Skin structure, functions and development -- Molecular control of cell differentiation -- What is epigenetics? -- What controls variability of skin phenotypes? …”
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Epigenetics and inheritance

Table of Contents: “…Contents: Definition of epigenetics -- Epigenetics and stem cell biology -- Mechanisms of inheritable epigenetics -- Examples of the epigenetic code -- Genomic imprinting -- Imprinting as a paradigm for epigenetic gene regulation and inheritance -- Developmental Origins of Health and Disease (DOHaD) definition -- Dutch hunger winter as an example of DOHaD -- IVF as a potential example of DOHaD -- IVF technology and imprinting disorders.…”
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Introduction to epigenetics

Table of Contents: “…Contents: Definition of epigenetics -- Three mechanisms; DNA methylation, histone modification, ncRNA -- Hypo and hyper DNA methylation and association with transcriptional state -- Mechanism of DNA methylation and enzymes responsible -- Examples of importance of DNA methytransferase enzymes -- Main types of histone modifications, concentrating on acetylation and methylation -- Mechanisms and enzymes for histone modifications -- Example of gene regulation by acetylation/deacetylation in Arabidopsis -- Non-coding RNA, using X-inactivation as an example -- The histone code.…”
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Epigenetic biomarkers in cancer

Table of Contents: “…Contents: Epigenetics -- levels of control -- The patient cancer journey-multiple impact points -- Key translational areas for epigenetics -- DNA methylation as cancer biomarker -- DNA methylation analysis methods -- Epigenetic gene silencing in malignant cells -- CpG methylation and clinical outcome -- Causes of aberrant DNA methylation in cancer -- Stem cell targets -- EZH2 as a potential anti-cancer target -- Epigenetic modification as drug targets -- Epigenetic therapies -- DNA methylation versus platinum resistance -- Phase II trial of Decitabine & Carboplatin -- Effects of low doses of DNA-demethylation agents -- Epigenetic therapies challenges.…”
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Polycomb epigenetic mechanisms Part 2 of 2, methylation of DNA /

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Epigenetics in age-related macular degeneration

Table of Contents: “…Contents: Epigenetics: terms and definitions -- Evidence for role of epigenetics in age-related macular degeneration (AMD) -- Future directions (potential for novel treatments for AMD).…”
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Role of polycomb proteins in gene transcription, stem cell and human diseases

“…Biomedical & life sciences collection. Epigenetics, chromatin, transcription and cancer.…”
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DNA methylation and genome defense in Neurospora crassa

“…Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.…”
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DNA methylation

“…Biomedical & life sciences collection. Epigenetics, chromatin, transcription and cancer.…”
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Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)

Epigenomics of complex disease

Table of Contents: “…Contents: Complex disease -- Non-mendelian features -- Epigenetic heritability -- Partial epigenetic stability -- Inherited and acquired epigenetic misregulation of genes and genomes -- Microarrays and epigenomic profiles in health and disease.…”
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DNA methylation changes in aging cells and tissues

Table of Contents: “…Contents: Epigenetics -- Phenotypic variation -- DNA methylation -- Promoter CpG & Non CpG islands -- The methylome -- DNA methylation changes in aging -- Hypermethylation and silencing -- Methylation in normal colon vs. age -- Microarray analysis of aging human colon -- Methylation in aging human prostate -- Methylation vs. age in human right atrium -- MCAM analysis of aging mouse colon -- Pyro analysis of aging mouse colon -- Age related methylation along the GI tract -- Epigenetic mosaicism -- Human carcinogenesis as an epigenetic disease -- Changes in tissue function -- Tissue function consequences of DNA methylation changes in aging -- Epigenetic variation in human colon -- Susceptibility to DNA hypermethylation -- DNA hypermethylation and retrotransposons -- Genome-wide analysis of methylation proneness -- Genome architecture and the prediction of hypermethylation -- Repeat element distribution and age-related methylation -- Polycomb targets and hypermethylated genes in aging.…”
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DNA methylation and stem cells

Table of Contents: “…Contents: Stem cells -- Pluripotent stem cells are extremely valuable for disease modeling and regenerative biology -- DNA methylation -- Stable epigenetic modification.…”
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DNA methylation as a tumor marker implications for diagnosis, early detection and risk assessment /

Table of Contents: “…Contents: How genes are silenced epigenetically via cytosine methylation and chromatin remodeling -- Assays for detecting gene promoter methylation in biological fluids -- Challenges for developing methylation-based assays -- Lung cancer case-control study of gene promoter methylation in sputum -- Predicting risk for lung cancer through gene methylation detection in plasma -- Gene promoter methylation as a diagnostic tool for lung, colon, prostate, and bladder cancer.…”
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