Search Results - T helper 17 cell

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    Interleukin-6 back to the future /

    Published 2011
    Table of Contents: “…Contents: IL-6 is a pleiotropic proinflammatory cytokine -- Its overproduction is involved in inflammatory autoimmune diseases including rheumatoid arthritis -- Blocking of IL-6 signals by anti-IL6 receptor antibody (Tocilizumab) shows therapeutic effect on various autoimmune diseases -- Tocilizumab exerts its effect by inhibiting the induction of a helper T cell subset (TH17) -- Aryl-hydrocarbon receptor (Ahr) is one of the essential molecule for the IL-6 mediated induction of TH17 cells.…”
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    Electronic Video