Search Results - "chromatin"
Suggested Topics within your search.
Suggested Topics within your search.
- Cell Cycle
- Genes, cdc 9
- Chromatids 3
- DNA Replication 3
- Cancer 2
- Cancer genes 2
- Cell Division 2
- Cell division 2
- Chromatin 2
- DNA-Binding Proteins 2
- Genes 2
- Genetic aspects 2
- Myc oncogenes 2
- Myc proteins 2
- Neoplasms 2
- Nuclear Proteins 2
- Prevention 2
- Proto-Oncogene Proteins c-myc 2
- Transcription Factors 2
- Transcription factors 2
- genetics 2
- metabolism 2
- physiology 2
-
1
The Myc transcription factor network
Published 2023Table of Contents: “…Contents: Myc plays a broad role in cellular functions -- Deregulation of Myc is associated with many cancers -- Myc and Mxd proteins heterodimerize with Max, bind DNA, and activate or repress transcription through recruitment of co-regulator complexes that in turn influence chromatin modifications -- Myc family proteins are highly conserved and regulate cell growth by binding to many genes involved in translation and metabolism -- Myc also has functions unrelated to transcription -- Update talk: The MYC transcription factor network -- Update talk: Interactions of MYC with other cellular proteins -- Update talk: Topologically Associated Domains (TADs) -- Update talk: Transcriptional functions of MYC -- Update talk: Proximal MYC network -- Update talk: New approaches to inhibiting MYC activity.…”
Get full text
Series (Cell division cycle)
Series (Epigenetics, chromatin, transcription and cancer)
Electronic Video -
2
The Myc transcription factor network
Published 2023Table of Contents: “…Contents: Myc plays a broad role in cellular functions -- Deregulation of Myc is associated with many cancers -- Myc and Mxd proteins heterodimerize with Max, bind DNA, and activate or repress transcription through recruitment of co-regulator complexes that in turn influence chromatin modifications -- Myc family proteins are highly conserved and regulate cell growth by binding to many genes involved in translation and metabolism -- Myc also has functions unrelated to transcription -- Update talk: The MYC transcription factor network -- Update talk: Interactions of MYC with other cellular proteins -- Update talk: Topologically Associated Domains (TADs) -- Update talk: Transcriptional functions of MYC -- Update talk: Proximal MYC network -- Update talk: New approaches to inhibiting MYC activity.…”
Get full text
Series (Cell division cycle)
Series (Epigenetics, chromatin, transcription and cancer)
Electronic Video -
3
Nucleosome assembly during DNA replication
Published 2009Table of Contents: “…Contents: Introduction to chromatin structure -- Primary function of chromatin: DNA compaction -- The nucleosome core particle -- De novo nucleosome assembly during the cell cycle -- Two distinct processes contribute to restoration of chromatin structure during DNA replication -- A fundamental problem in nucleosome assembly: histone-DNA aggregation -- Chromatin Assembly Factor 1 (CAF-1) and PCNA -- ASF1: a multi-talented histone chaperone -- Biomedical implications -- Agents that block the acetylation and deacetylation of new histones may sensitise cells to cancer chemotherapeutic agents -- Genome-wide histone acetylation, deacetylation and epigenetic inheritance -- Epigenetic xerox machines as potential targets for cancer therapy and regenerative medicine.…”
Get full text
Series
Electronic Video -
4
Nucleosome assembly during DNA replication
Published 2009Table of Contents: “…Contents: Introduction to chromatin structure -- Primary function of chromatin: DNA compaction -- The nucleosome core particle -- De novo nucleosome assembly during the cell cycle -- Two distinct processes contribute to restoration of chromatin structure during DNA replication -- A fundamental problem in nucleosome assembly: histone-DNA aggregation -- Chromatin Assembly Factor 1 (CAF-1) and PCNA -- ASF1: a multi-talented histone chaperone -- Biomedical implications -- Agents that block the acetylation and deacetylation of new histones may sensitise cells to cancer chemotherapeutic agents -- Genome-wide histone acetylation, deacetylation and epigenetic inheritance -- Epigenetic xerox machines as potential targets for cancer therapy and regenerative medicine.…”
Get full text
Series
Electronic Video -
5
Nucleosome assembly during DNA replication
Published 2009Table of Contents: “…Contents: Introduction to chromatin structure -- Primary function of chromatin: DNA compaction -- The nucleosome core particle -- De novo nucleosome assembly during the cell cycle -- Two distinct processes contribute to restoration of chromatin structure during DNA replication -- A fundamental problem in nucleosome assembly: histone-DNA aggregation -- Chromatin Assembly Factor 1 (CAF-1) and PCNA -- ASF1: a multi-talented histone chaperone -- Biomedical implications -- Agents that block the acetylation and deacetylation of new histones may sensitise cells to cancer chemotherapeutic agents -- Genome-wide histone acetylation, deacetylation and epigenetic inheritance -- Epigenetic xerox machines as potential targets for cancer therapy and regenerative medicine.…”
Get full text
Series
Electronic Video -
6
Mitotic chromosome condensation
Published 2009Table of Contents: “…Contents: Evolutionary and developmental comparisons -- Stages of mitosis -- Primary functions of mitosis -- Lower levels of chromatin organization -- Helical folding -- Experimental foundation of textbook model -- Are there specific DNA sequences at the base of chromatin loops? …”
Get full text
Series
Electronic Video -
7
Initiation of DNA replication
Published 2009Table of Contents: “…Contents: Cell cycle control of DNA replication -- Yeast as a model eukaryote -- Control of S-phase entry in yeast -- Characterization of origins of DNA replication -- Modular structure of S. cerevisiae origins -- The budding yeast origin recognition complex (ORC) -- Structure of the ORC-Cdc6 complex -- Evolutionary comparison of ORC AAA+ subunits -- Proteins required for formation of the pre-Replication Complex (pre-RC) -- Cell cycle dependent association of yeast initiation proteins with chromatin -- ATP-dependent assembly of a pre-RC -- Cell cycle regulation of the pre-RC -- The chromosome cycle and establishment of pre-RCs -- Dynamic assembly and stability of ORC in human cells -- Commitment to S-phase and initiation -- Cdc45p is associated with chromatin in a cell cycle-dependent manner -- Temporal regulation of DNA replication -- Dynamics of pre-RC proteins in human cells differ from pre-RC proteins in yeast.…”
Get full text
Series
Electronic Video -
8
Mitotic chromosome condensation
Published 2009Table of Contents: “…Contents: Evolutionary and developmental comparisons -- Stages of mitosis -- Primary functions of mitosis -- Lower levels of chromatin organization -- Helical folding -- Experimental foundation of textbook model -- Are there specific DNA sequences at the base of chromatin loops? …”
Get full text
Series
Electronic Video -
9
Initiation of DNA replication
Published 2009Table of Contents: “…Contents: Cell cycle control of DNA replication -- Yeast as a model eukaryote -- Control of S-phase entry in yeast -- Characterization of origins of DNA replication -- Modular structure of S. cerevisiae origins -- The budding yeast origin recognition complex (ORC) -- Structure of the ORC-Cdc6 complex -- Evolutionary comparison of ORC AAA+ subunits -- Proteins required for formation of the pre-Replication Complex (pre-RC) -- Cell cycle dependent association of yeast initiation proteins with chromatin -- ATP-dependent assembly of a pre-RC -- Cell cycle regulation of the pre-RC -- The chromosome cycle and establishment of pre-RCs -- Dynamic assembly and stability of ORC in human cells -- Commitment to S-phase and initiation -- Cdc45p is associated with chromatin in a cell cycle-dependent manner -- Temporal regulation of DNA replication -- Dynamics of pre-RC proteins in human cells differ from pre-RC proteins in yeast.…”
Get full text
Series
Electronic Video -
10
Initiation of DNA replication
Published 2009Table of Contents: “…Contents: Cell cycle control of DNA replication -- Yeast as a model eukaryote -- Control of S-phase entry in yeast -- Characterization of origins of DNA replication -- Modular structure of S. cerevisiae origins -- The budding yeast origin recognition complex (ORC) -- Structure of the ORC-Cdc6 complex -- Evolutionary comparison of ORC AAA+ subunits -- Proteins required for formation of the pre-Replication Complex (pre-RC) -- Cell cycle dependent association of yeast initiation proteins with chromatin -- ATP-dependent assembly of a pre-RC -- Cell cycle regulation of the pre-RC -- The chromosome cycle and establishment of pre-RCs -- Dynamic assembly and stability of ORC in human cells -- Commitment to S-phase and initiation -- Cdc45p is associated with chromatin in a cell cycle-dependent manner -- Temporal regulation of DNA replication -- Dynamics of pre-RC proteins in human cells differ from pre-RC proteins in yeast.…”
Get full text
Series
Electronic Video -
11
Mitotic chromosome condensation
Published 2009Table of Contents: “…Contents: Evolutionary and developmental comparisons -- Stages of mitosis -- Primary functions of mitosis -- Lower levels of chromatin organization -- Helical folding -- Experimental foundation of textbook model -- Are there specific DNA sequences at the base of chromatin loops? …”
Get full text
Series
Electronic Video -
12
Sister chromatid cohesion simple concept, complex reality /
Published 2009Table of Contents: “…Contents: Sister chromatid cohesion: simple concept complex reality -- Overview of higher order chromosome structure -- Smc (structural maintenance of chromosomes) complexes as mediators of higher order chromosome structure -- Introduction to cohesin, the Smc complex that mediates sister chromatid cohesion -- Biological function of cohesion -- Cohesin binding to chromatin -- Establishment, maintenance and dissolution of cohesion -- The molecular basis of cohesins as chromatid tethers.…”
Get full text
Series
Electronic Video -
13
Sister chromatid cohesion simple concept, complex reality /
Published 2009Table of Contents: “…Contents: Sister chromatid cohesion: simple concept complex reality -- Overview of higher order chromosome structure -- Smc (structural maintenance of chromosomes) complexes as mediators of higher order chromosome structure -- Introduction to cohesin, the Smc complex that mediates sister chromatid cohesion -- Biological function of cohesion -- Cohesin binding to chromatin -- Establishment, maintenance and dissolution of cohesion -- The molecular basis of cohesins as chromatid tethers.…”
Get full text
Series
Electronic Video -
14
Sister chromatid cohesion simple concept, complex reality /
Published 2009Table of Contents: “…Contents: Sister chromatid cohesion: simple concept complex reality -- Overview of higher order chromosome structure -- Smc (structural maintenance of chromosomes) complexes as mediators of higher order chromosome structure -- Introduction to cohesin, the Smc complex that mediates sister chromatid cohesion -- Biological function of cohesion -- Cohesin binding to chromatin -- Establishment, maintenance and dissolution of cohesion -- The molecular basis of cohesins as chromatid tethers.…”
Get full text
Series
Electronic Video