Search Results - "glucose"

O-GlcNAc, an essential regulator of numerous cellular pathways

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O-GlcNAc, an essential regulator of numerous cellular pathways

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O-GlcNAc, an essential regulator of numerous cellular pathways

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Roles of AMPK in energy homeostasis and nutrient sensing

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Roles of AMPK in energy homeostasis and nutrient sensing

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PI3K/AKT signaling In cancer

Table of Contents: “…Contents: PI3K/AKT signal transduction pathway -- Tumors with frequent dysregulation of PI3K signalling -- Modalities for inhibiting PI3K-AKT signaling currently in development -- AKT1/2 inhibitor (Merck) -- PI3K/AKT in breast cancer -- AKTi-1/2 inhibits AKT signaling and causes G1 arrest -- The Herceptin-resistant -- Effect of AKT inhibition on glucose levels -- Mutated elements in mitogenic signaling pathways in tumors -- Coexistent K-Ras or B-Raf mutation -- Genes encoding several components of mitogenic signaling pathways are mutationally activated in tumors -- Integrators of multiple signaling pathways (OR-gates) -- The effects of combined inhibition of AKT and MAPK on the phosphorylation of translational regulatory proteins -- Knockdown of 4EBP1 expression -- Feedback inhibition of insulin/IGF-1 signaling -- The concept of feedback -- Clinical effects of Rapamycin-like drugs -- mTORC1 vs. …”
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PI3K/AKT signaling In cancer

Table of Contents: “…Contents: PI3K/AKT signal transduction pathway -- Tumors with frequent dysregulation of PI3K signalling -- Modalities for inhibiting PI3K-AKT signaling currently in development -- AKT1/2 inhibitor (Merck) -- PI3K/AKT in breast cancer -- AKTi-1/2 inhibits AKT signaling and causes G1 arrest -- The Herceptin-resistant -- Effect of AKT inhibition on glucose levels -- Mutated elements in mitogenic signaling pathways in tumors -- Coexistent K-Ras or B-Raf mutation -- Genes encoding several components of mitogenic signaling pathways are mutationally activated in tumors -- Integrators of multiple signaling pathways (OR-gates) -- The effects of combined inhibition of AKT and MAPK on the phosphorylation of translational regulatory proteins -- Knockdown of 4EBP1 expression -- Feedback inhibition of insulin/IGF-1 signaling -- The concept of feedback -- Clinical effects of Rapamycin-like drugs -- mTORC1 vs. …”
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Series

PI3K/AKT signaling In cancer

Table of Contents: “…Contents: PI3K/AKT signal transduction pathway -- Tumors with frequent dysregulation of PI3K signalling -- Modalities for inhibiting PI3K-AKT signaling currently in development -- AKT1/2 inhibitor (Merck) -- PI3K/AKT in breast cancer -- AKTi-1/2 inhibits AKT signaling and causes G1 arrest -- The Herceptin-resistant -- Effect of AKT inhibition on glucose levels -- Mutated elements in mitogenic signaling pathways in tumors -- Coexistent K-Ras or B-Raf mutation -- Genes encoding several components of mitogenic signaling pathways are mutationally activated in tumors -- Integrators of multiple signaling pathways (OR-gates) -- The effects of combined inhibition of AKT and MAPK on the phosphorylation of translational regulatory proteins -- Knockdown of 4EBP1 expression -- Feedback inhibition of insulin/IGF-1 signaling -- The concept of feedback -- Clinical effects of Rapamycin-like drugs -- mTORC1 vs. …”
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The genetic basis of kidney cancer

Table of Contents: “…-- Folliculin-FNIP1/2-AMPK interactions -- mTORC1/mTORC2 activation: FLCN-deficient Kidney Cancer -- BHD deletion specifically in the kidney -- BHDf/d/KSPCre mouse kidney study -- Hereditary Leiomyomatosis Renal Cell Carcinoma (HLRCC) -- HLRCC: cutaneous manifestations, Uterine Leiomyomas -- HLRCC: Papillary Kidney Cancer Type 2 -- Orangophilic nucleoli + Perinucleolar halos -- Fumarate Hydratase gene: HLRCC -- UOK-262 study -- Loss of a Krebs Cycle Enzyme can lead to Kidney Cancer -- Impaired citric acid cycle and "Warburg effect" -- HLRCC-Renal Cancer: glucose-dependent -- PET scan -- HLRCC novel treatment approaches -- Kidney cancer: a metabolic disease.…”
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Series (Molecular genetics of human disease)
Series (Kidney in health and disease)

The genetic basis of kidney cancer

Table of Contents: “…-- Folliculin-FNIP1/2-AMPK interactions -- mTORC1/mTORC2 activation: FLCN-deficient Kidney Cancer -- BHD deletion specifically in the kidney -- BHDf/d/KSPCre mouse kidney study -- Hereditary Leiomyomatosis Renal Cell Carcinoma (HLRCC) -- HLRCC: cutaneous manifestations, Uterine Leiomyomas -- HLRCC: Papillary Kidney Cancer Type 2 -- Orangophilic nucleoli + Perinucleolar halos -- Fumarate Hydratase gene: HLRCC -- UOK-262 study -- Loss of a Krebs Cycle Enzyme can lead to Kidney Cancer -- Impaired citric acid cycle and "Warburg effect" -- HLRCC-Renal Cancer: glucose-dependent -- PET scan -- HLRCC novel treatment approaches -- Kidney cancer: a metabolic disease.…”
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Series (Molecular genetics of human disease)
Series (Kidney in health and disease)

The genetic basis of kidney cancer

Table of Contents: “…-- Folliculin-FNIP1/2-AMPK interactions -- mTORC1/mTORC2 activation: FLCN-deficient Kidney Cancer -- BHD deletion specifically in the kidney -- BHDf/d/KSPCre mouse kidney study -- Hereditary Leiomyomatosis Renal Cell Carcinoma (HLRCC) -- HLRCC: cutaneous manifestations, Uterine Leiomyomas -- HLRCC: Papillary Kidney Cancer Type 2 -- Orangophilic nucleoli + Perinucleolar halos -- Fumarate Hydratase gene: HLRCC -- UOK-262 study -- Loss of a Krebs Cycle Enzyme can lead to Kidney Cancer -- Impaired citric acid cycle and "Warburg effect" -- HLRCC-Renal Cancer: glucose-dependent -- PET scan -- HLRCC novel treatment approaches -- Kidney cancer: a metabolic disease.…”
Get full text
Series (Molecular genetics of human disease)
Series (Kidney in health and disease)