Search Results - "Therapeutic approach"

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  1. 1

    Mitochondrial inhibition as a novel therapeutic approach in drug-resistant cancer

    Published 2017
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    Electronic Video
  2. 2

    Mitochondrial inhibition as a novel therapeutic approach in drug-resistant cancer

    Published 2017
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    Electronic Video
  3. 3

    Mitochondrial inhibition as a novel therapeutic approach in drug-resistant cancer

    Published 2017
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    Electronic Video
  4. 4
  5. 5

    The genetic basis of kidney cancer

    Published 2014
    Table of Contents: “…Contents: Renal carcinoma -- Stage I , Stage IV Kidney Cancer -- Human renal epithelial neoplasms -- Loss of alleles in Renal Cell Carcinoma -- Mapping the minimal 3p loss region in Clear Cell Renal Carcinoma -- Studying cancer families to identify renal carcinoma genes -- Identification of kidney cancer genes -- Inherited forms of renal carcinoma -- Clear cell Renal Carcinoma: von Hippel Lindau (VHL) -- VHL gene -- VHL gene localization map -- Germline VHL mutations -- Papillary Renal Carcinoma -- Mouse studies of VHL gene -- VHL gene function -- HIFα -- Downstream effects of VHL mutation -- Targeting VHL/HIF in Clear Cell RCC -- TCGA Clear Cell Kidney Cancer -- Intratumor heterogeneity -- Warburg effect in Clear Cell Kidney Cancer -- Non-Clear Cell RCC -- Locally advanced Kidney Cancer -- Hereditary Papillary Renal Carcinoma (HPRC) -- Inherited Renal Carcinoma -- Type 1 Papillary Renal Carcinoma -- Penetrance of MET mutation H1210R -- MET gene: Type 1 Papillary RCC -- Location of the HPRC gene -- HPRC: Activating mutations in the Tyrosine Kinase domain of MET -- Location of MET mutations in the HPRC patients -- Targeting MET RCC gene pathway -- Potential small molecule target: MET Tyrosine Kinase inhibition -- Foretinib: Dual VEGFR and MET Inhibitor -- MiT Kidney Cancer TFE3, TFEB, MITF -- UOK124, Papillary Kidney Cancer -- UOK124, UOK120, UOK 146 & TFE3 Kidney Cancer -- Inherited Renal Carcinoma Birt-Hogg-Dubé (BHD) -- Birt Hogg Dubé cutaneous manifestations -- Kidney tumors in BHD -- BHD renal tumor pathology -- BHD lung cysts -- Identification of the BHD Gene -- Cutaneous Fibrofolliculomas -- BHD Gene: Chromophobe RCC -- BHD Gene Locus: Chromosome 17 -- BHD Protein Sequence -- FLCN Mutation Spectrum -- Therapeutic Approach: What Kind of Gene is FLCN? -- BHD Gene Analysis in BHD-Associated RCC -- Somatic mutations in renal Tumors from BHD patients -- UOK 257, BHD -/- RCC cell line study -- How does the FLCN gene function? …”
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    Series (Molecular genetics of human disease)
    Series (Kidney in health and disease)
    Electronic Video
  6. 6

    The genetic basis of kidney cancer

    Published 2014
    Table of Contents: “…Contents: Renal carcinoma -- Stage I , Stage IV Kidney Cancer -- Human renal epithelial neoplasms -- Loss of alleles in Renal Cell Carcinoma -- Mapping the minimal 3p loss region in Clear Cell Renal Carcinoma -- Studying cancer families to identify renal carcinoma genes -- Identification of kidney cancer genes -- Inherited forms of renal carcinoma -- Clear cell Renal Carcinoma: von Hippel Lindau (VHL) -- VHL gene -- VHL gene localization map -- Germline VHL mutations -- Papillary Renal Carcinoma -- Mouse studies of VHL gene -- VHL gene function -- HIFα -- Downstream effects of VHL mutation -- Targeting VHL/HIF in Clear Cell RCC -- TCGA Clear Cell Kidney Cancer -- Intratumor heterogeneity -- Warburg effect in Clear Cell Kidney Cancer -- Non-Clear Cell RCC -- Locally advanced Kidney Cancer -- Hereditary Papillary Renal Carcinoma (HPRC) -- Inherited Renal Carcinoma -- Type 1 Papillary Renal Carcinoma -- Penetrance of MET mutation H1210R -- MET gene: Type 1 Papillary RCC -- Location of the HPRC gene -- HPRC: Activating mutations in the Tyrosine Kinase domain of MET -- Location of MET mutations in the HPRC patients -- Targeting MET RCC gene pathway -- Potential small molecule target: MET Tyrosine Kinase inhibition -- Foretinib: Dual VEGFR and MET Inhibitor -- MiT Kidney Cancer TFE3, TFEB, MITF -- UOK124, Papillary Kidney Cancer -- UOK124, UOK120, UOK 146 & TFE3 Kidney Cancer -- Inherited Renal Carcinoma Birt-Hogg-Dubé (BHD) -- Birt Hogg Dubé cutaneous manifestations -- Kidney tumors in BHD -- BHD renal tumor pathology -- BHD lung cysts -- Identification of the BHD Gene -- Cutaneous Fibrofolliculomas -- BHD Gene: Chromophobe RCC -- BHD Gene Locus: Chromosome 17 -- BHD Protein Sequence -- FLCN Mutation Spectrum -- Therapeutic Approach: What Kind of Gene is FLCN? -- BHD Gene Analysis in BHD-Associated RCC -- Somatic mutations in renal Tumors from BHD patients -- UOK 257, BHD -/- RCC cell line study -- How does the FLCN gene function? …”
    Get full text
    Series (Molecular genetics of human disease)
    Series (Kidney in health and disease)
    Electronic Video
  7. 7

    The genetic basis of kidney cancer

    Published 2014
    Table of Contents: “…Contents: Renal carcinoma -- Stage I , Stage IV Kidney Cancer -- Human renal epithelial neoplasms -- Loss of alleles in Renal Cell Carcinoma -- Mapping the minimal 3p loss region in Clear Cell Renal Carcinoma -- Studying cancer families to identify renal carcinoma genes -- Identification of kidney cancer genes -- Inherited forms of renal carcinoma -- Clear cell Renal Carcinoma: von Hippel Lindau (VHL) -- VHL gene -- VHL gene localization map -- Germline VHL mutations -- Papillary Renal Carcinoma -- Mouse studies of VHL gene -- VHL gene function -- HIFα -- Downstream effects of VHL mutation -- Targeting VHL/HIF in Clear Cell RCC -- TCGA Clear Cell Kidney Cancer -- Intratumor heterogeneity -- Warburg effect in Clear Cell Kidney Cancer -- Non-Clear Cell RCC -- Locally advanced Kidney Cancer -- Hereditary Papillary Renal Carcinoma (HPRC) -- Inherited Renal Carcinoma -- Type 1 Papillary Renal Carcinoma -- Penetrance of MET mutation H1210R -- MET gene: Type 1 Papillary RCC -- Location of the HPRC gene -- HPRC: Activating mutations in the Tyrosine Kinase domain of MET -- Location of MET mutations in the HPRC patients -- Targeting MET RCC gene pathway -- Potential small molecule target: MET Tyrosine Kinase inhibition -- Foretinib: Dual VEGFR and MET Inhibitor -- MiT Kidney Cancer TFE3, TFEB, MITF -- UOK124, Papillary Kidney Cancer -- UOK124, UOK120, UOK 146 & TFE3 Kidney Cancer -- Inherited Renal Carcinoma Birt-Hogg-Dubé (BHD) -- Birt Hogg Dubé cutaneous manifestations -- Kidney tumors in BHD -- BHD renal tumor pathology -- BHD lung cysts -- Identification of the BHD Gene -- Cutaneous Fibrofolliculomas -- BHD Gene: Chromophobe RCC -- BHD Gene Locus: Chromosome 17 -- BHD Protein Sequence -- FLCN Mutation Spectrum -- Therapeutic Approach: What Kind of Gene is FLCN? -- BHD Gene Analysis in BHD-Associated RCC -- Somatic mutations in renal Tumors from BHD patients -- UOK 257, BHD -/- RCC cell line study -- How does the FLCN gene function? …”
    Get full text
    Series (Molecular genetics of human disease)
    Series (Kidney in health and disease)
    Electronic Video