Search Results - "yeast"

Yeast studies on ageing

Table of Contents: “…Contents: History of studies on yeast ageing -- Senescence factor, molecular memory, and age locus -- Mitochondria and ageing -- Age asymmetry and cell quality control -- Epigenetic gene regulation and ageing -- Genome instability as a cause of ageing -- Replicative and chronological lifespans -- Nutrient effects on lifespan -- Ageing in the wild.…”
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Impact of systems biology on metabolic engineering

Table of Contents: “…Contents: The biorefinery concept -- The process of metabolic engineering (ME) -- Approaches in systems biology (SB) -- Genome scale metabolic models (GEMs) -- Using SB to design succinic acid production in yeast -- Using SB to compare metabolism of yeast strains -- Using SB to compare penicillin producing in yeast strains -- Inverse metabolic engineering -- Using inverse ME to improve galactose utilization in yeast -- Mechanisms of evolutionary trade-offs.…”
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Computational methods in analysis of gene regulation and protein interactions

Table of Contents: “…Contents: Finding regulatory motifs -- Finding motifs using target sets of promoters -- Problem definition -- The Amadeus motif finding algorithm -- Architecture, benchmark results and global analysis -- Finding transcriptional programs and their regulatory motifs -- Problem definition -- The Allegro software for recovering transcriptional program -- Results on yeast osmotic shock expression profiles -- Recovering microRNA binding motifs from 3' UTRs using stem cell expression profiles -- Discovering a novel motif pair in C. elegans -- Utilizing network information -- Using expression and protein interaction data -- Problem definition and the Matisse algorithm -- Demonstration of Matisse on yeast osmotic shock data -- Comparison of Matisse to other algorithms -- Demonstration of Matisse on human stem cell data -- The pluripotency network -- Using expression and protein interaction data with interaction confidence -- The Cezanne algorithm -- DNA damage response in yeast.…”
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Computational modelling of GPCR signalling dynamics

Table of Contents: “…Contents: GPCRs signalling kinetics can be modelled using simple equations -- Link between computational modelling and pharmacology -- Yeast are excellent system for computational models -- RGS proteins show non-intuitive activity -- Kinetic models of GPCRs can model agonist bias.…”
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