Search Results - "cell adhesion"

CD44 genetic deletion enhances and CD44 antibody targeting attenuates autoimmune inflammation

Table of Contents: “…Contents: CD44 and RHAMM (receptor for hyaluronan-mediated motility) are cell adhesion and cell homing receptors -- Cell migration -- Generation of different CD44 isoforms -- RHAMM also supports cell motility and is engaged in intracellular signalling -- Collagen-induced arthritis and type 1 diabetes are CD44-dependent pathologies -- Molecular redundancy -- CD44 targeting by anti-CD44 mAb may eradicate not only malignant cells and destructive inflammatory cells but also CD44-expressing normal cells which are committed to physiological functions.…”
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