Search Results - "melanoma"

Update on therapies for metastatic melanoma

Table of Contents: “…Contents: Overview of new treatments approved for advanced melanoma in the past few years -- Pegylated interferon alfa-2b -- Ipilimumab -- Mechanism of action -- Impact on progression-free and overall survival -- Overview of immune-related adverse events -- Vemurafenib -- Mechanism of action -- Impact on progression-free and overall survival -- Induction of secondary squamous cell carcinomas -- Possible role for combined RAF/MEK inhibition -- A "standard" approach to treatment of stage IV melanoma.…”
Get full text

Immune checkpoint blockade in melanoma

Table of Contents: “…Contents: Checkpoint inhibition in melanoma -- Immunotherapy in the adjuvant setting -- Biomarkers of immune response -- The future of immunotherapy in melanoma -- Targeting release of cancer antigens -- Targeting cancer antigen presentation -- Targeting priming and activation of the immune system -- Targeting trafficking and infiltration of T-cells -- Targeting recognition and killing of cancer cells.…”
Get full text
Series

Checkpoint blockade in cancer immunotherapy

Table of Contents: “…Contents: Activation of naive T-cells -- CD28 and CTLA-4 -- Differential regulation of T-cell responses -- Responding repertoire -- Biological role of CTLA-4 -- Tumor-specific immune responses -- Treg activity -- CTLA-4/GVax -- Immunotherapies -- Conventional therapies -- Ipilumumab -- Clinical studies: melanoma -- Reversible immune mediated toxicity.…”
Get full text
Series

Diagnostic immunohistopathology

Table of Contents: “…Contents: Techniques for identification and immunocytochemical study of proteins -- Leucocyte-associated molecules -- Immunhistological labeling -- Immunohistological studies of human tissue -- The first monoclonal anti-leucocyte antibodies -- Paraffin reactive monoclonal antibodies -- Protein conformation and antigenicity -- Immunohistological markers for the study of solid tumors -- Carcinoma, seminoma, mesothelioma, melanoma and carcinoid tumors -- Immunohistological markers for the diagnosis of lymphoid neoplasms -- Anaplastic large cell lymphoma -- New labeling techniques -- New antibodies and molecular targets.…”
Get full text
Series