Search Results - "Cancer"

Cancer immunotherapy

Subjects: “…Cancer Immunotherapy. 84884…”
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Series (Immune system)
Series (Molecular basis of cancer)

Checkpoint blockade in cancer immunotherapy

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Human tumor antigens as therapeutic targets of cancer

Table of Contents: “…Contents: Products of oncogenes as therapeutic targets -- Differentiation antigens as therapeutic targets -- Angiogenesis associated antigens as therapeutic targets -- Endoglin-targeted cancer therapy.…”
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Monoclonal antibodies and the ErbB system in human cancer

Table of Contents: “…Contents: General properties of tumor cells -- Human breast cancer and the erbB2/neu oncogene and protein -- Targeted monoclonal antibodies -- Tyrosine kinase activity and dimerization -- Activation of the kinase of erbB2/neu -- Overexpression of erbB2/neu and EGFr -- The erbB family members -- Discussion of Herceptin -- Prevention of tumor growth in a neoadjuvant model -- Two antibody therapy & tumor growth inhibition.…”
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Anti-IL-2 receptor antibodies as models for cancer therapy

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Immune checkpoint blockade in renal cell carcinoma

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Series (Immunotherapy of cancer)
Series (Kidney in health and disease)

The development of therapeutic antibodies against oncogenic antigens

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The evolving role of novel and next generation therapies in the management of multiple myeloma part 2 of 2, relapse refractory multiple myeloma /

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Immune checkpoint blockade in melanoma

Table of Contents: “…Contents: Checkpoint inhibition in melanoma -- Immunotherapy in the adjuvant setting -- Biomarkers of immune response -- The future of immunotherapy in melanoma -- Targeting release of cancer antigens -- Targeting cancer antigen presentation -- Targeting priming and activation of the immune system -- Targeting trafficking and infiltration of T-cells -- Targeting recognition and killing of cancer cells.…”
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Therapeutic antibodies

Table of Contents: “…Contents: Why antibodies are so useful as drugs -- Antibody therapy -- The development of monoclonal antibodies -- Genetic engineering -- The problem of unwanted immunogenicity -- The importance of affinity -- Examples of antibodies for treatment of cancer -- Examples of antibodies for treatment of immunological diseases.…”
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The challenge of targeting toxins to tumors

Table of Contents: “…Contents: Generation of immunotoxins -- Mode of action of different immunotoxins -- Strategies to overcome the major impediments in the therapeutic application of immunotoxins to cancer patients -- Anti-endoglin monoclonal antibodies and immunotoxins -- Anti-angiogenic therapy of tumors -- Vascular targeting therapy of tumors -- Comparison between immunotoxins and naked antibodies in therapeutic application.…”
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Monoclonal antibodies in haemato-oncology

Table of Contents: “…Contents: Introduction to the development and clinical use of monoclonal antibodies (mAb) in haemato-oncology -- Currently approved mAb for treating cancer -- Direct targeting antibodies -- Rituximab -- Fc gamma receptors (FcgR) as key mediators of cellular immunity -- Macrophages as key effector cells -- B cell deletion as a paradigm for mAb effects -- Type I versus Type II antibodies -- Obinutuzumab -- Immunomodulatory mAb -- Combinations between direct targeting and immunomodulatory mAb.…”
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Series (Monoclonal antibodies as therapeutic agents)
Series (Immune system)