Search Results - "amyloid"
Suggested Topics within your search.
Suggested Topics within your search.
- Alzheimer Disease
- Alzheimer's disease 35
- pathology 16
- Neurodegenerative Diseases 15
- physiopathology 15
- genetics 14
- Amyloid 13
- Amyloid beta-Peptides 13
- Genetic aspects 13
- Chemotherapy 12
- drug therapy 12
- Degeneration 11
- Nervous system 11
- metabolism 11
- Amyloid beta-protein 9
- Pathophysiology 9
- Treatment 9
- therapy 9
- Brain 8
- Dementia 8
- Pathology 8
- Diagnosis 7
- Diagnostic Imaging 6
- etiology 6
- toxicity 6
- Biomarkers 5
- Blood-Brain Barrier 5
- Drug Discovery 5
- Risk Factors 5
- diagnosis 5
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1
Imaging amyloid now that we can see it, what does it all mean? /
Published 2010Table of Contents: “…Contents: Amyloid imaging PET tracers -- Development and validation -- Amyloid imaging in dementia -- Amyloid imaging in mild cognitive impairment -- Amyloid imaging in cognitively normal elderly -- Consequences of being amyloid-positive.…”
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Electronic Video -
2
Imaging amyloid now that we can see it, what does it all mean? /
Published 2010Table of Contents: “…Contents: Amyloid imaging PET tracers -- Development and validation -- Amyloid imaging in dementia -- Amyloid imaging in mild cognitive impairment -- Amyloid imaging in cognitively normal elderly -- Consequences of being amyloid-positive.…”
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Series
Electronic Video -
3
Imaging amyloid now that we can see it, what does it all mean? /
Published 2010Table of Contents: “…Contents: Amyloid imaging PET tracers -- Development and validation -- Amyloid imaging in dementia -- Amyloid imaging in mild cognitive impairment -- Amyloid imaging in cognitively normal elderly -- Consequences of being amyloid-positive.…”
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Series
Electronic Video -
4
Ischemic blood-brain barrier and Alzheimer's amyloid plaques development
Published 2008Table of Contents: “…Contents: Ischemic blood-brain barrier involved in Alzheimer's amyloid plaques development and full-blown Alzheimer's disease -- Brain ischemia starts Alzheimer's disease -- Association and risk factors for Alzheimer's disease -- Ischemic mechanisms in Alzheimer's disease in general.…”
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Electronic Video -
5
Ischemic blood-brain barrier and Alzheimer's amyloid plaques development
Published 2008Table of Contents: “…Contents: Ischemic blood-brain barrier involved in Alzheimer's amyloid plaques development and full-blown Alzheimer's disease -- Brain ischemia starts Alzheimer's disease -- Association and risk factors for Alzheimer's disease -- Ischemic mechanisms in Alzheimer's disease in general.…”
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Series
Electronic Video -
6
Ischemic blood-brain barrier and Alzheimer's amyloid plaques development
Published 2008Table of Contents: “…Contents: Ischemic blood-brain barrier involved in Alzheimer's amyloid plaques development and full-blown Alzheimer's disease -- Brain ischemia starts Alzheimer's disease -- Association and risk factors for Alzheimer's disease -- Ischemic mechanisms in Alzheimer's disease in general.…”
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Series
Electronic Video -
7
Abeta toxicity Part 2 /
Published 2011Table of Contents: “…Contents: The Australian imaging, biomarkers and lifestyle (aibl) flagship study of ageing -- Methodology: key outcomes -- Abeta and amyloid imaging -- The progression of AD -- Abeta and memory -- Prediction of conversion from HC to MCI/AD -- Impact of amyloid imaging in MCI patient selection for anti-amyloid therapeutic trials -- Longitudinal PiB PET follow-up -- Plasma Abeta 42 levels in the PiB-PET AIBL subset -- Relation between Abeta oligomers in blood cellular elements, cognition and PiB SUVR -- Plasma ApoE (total) levels: the AIBL study -- Biomarker discovery -- Abeta deposition.…”
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Series (Alzheimer's disease)
Series (Drug discovery and development in the neurosciences)
Electronic Video -
8
Abeta toxicity Part 1 /
Published 2011Table of Contents: “…Contents: The amyloid plaque -- Impact of delaying onset of AD -- The amyloidocentric theory of Alzheimer's disease -- Compelling evidence for the Abeta theory of AD -- Delay onset of AD by 5 years -- The best target for a disease-modifying drug -- APP structure and domains -- Iron-export ferroxidase activity of beta-amyloid precursor protein -- Age at onset correlates with Abeta isoforms -- Activation of PS1 -- Abeta amyloid -- The mechanism of neurodegeneration -- Abeta metal binding modes -- Current working model of Abeta toxicity -- Abeta amyloid protein: current model consistent with EXAFS -- Metal-protein attenuating compound (MPAC) with moderate affinity for metals -- Clioquinol (CQ, PBT1) the prototypic MPAC -- PBT2: SAR based on rational drug design -- CQ (PBT1) vs. …”
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Series (Alzheimer disease)
Series (Drug discovery and development in the neurosciences)
Electronic Video -
9
A molecular understanding of Alzheimer's disease
Published 2007Table of Contents: “…Contents: Usefulness of genetics in understanding AD -- Pathology of diseases -- Amyloid protein -- Genetic maps -- Mechanism of late onset Alzheimer's -- Role of presenilin in amyloid pathology -- Tau and frontotemporal dementia -- Tau splice site mutations -- Pathways to neurodegeneration.…”
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Series
Electronic Video -
10
Abeta toxicity 2
Published 2011Table of Contents: “…Contents: The Australian imaging, biomarkers and lifestyle (aibl) flagship study of ageing -- Methodology: key outcomes -- Abeta and amyloid imaging -- The progression of AD -- Abeta and memory -- Prediction of conversion from HC to MCI/AD -- Impact of amyloid imaging in MCI patient selection for anti-amyloid therapeutic trials -- Longitudinal PiB PET follow-up -- Plasma Abeta 42 levels in the PiB-PET AIBL subset -- Relation between Abeta oligomers in blood cellular elements, cognition and PiB SUVR -- Plasma ApoE (total) levels: the AIBL study -- Biomarker discovery -- Abeta deposition.…”
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Series (Alzheimer's disease)
Series (Drug discovery and development in the neurosciences)
Electronic Video -
11
Abeta toxicity 2
Published 2011Table of Contents: “…Contents: The Australian imaging, biomarkers and lifestyle (aibl) flagship study of ageing -- Methodology: key outcomes -- Abeta and amyloid imaging -- The progression of AD -- Abeta and memory -- Prediction of conversion from HC to MCI/AD -- Impact of amyloid imaging in MCI patient selection for anti-amyloid therapeutic trials -- Longitudinal PiB PET follow-up -- Plasma Abeta 42 levels in the PiB-PET AIBL subset -- Relation between Abeta oligomers in blood cellular elements, cognition and PiB SUVR -- Plasma ApoE (total) levels: the AIBL study -- Biomarker discovery -- Abeta deposition.…”
Get full text
Series (Alzheimer's disease)
Series (Drug discovery and development in the neurosciences)
Electronic Video -
12
Current directions in the prevention and treatment of Alzheimer's disease
Published 2018Table of Contents: “…Contents: Amyloid build-up and the importance of early diagnosis -- The potential of inhibiting vs. clearing amyloid aggregation -- Different potential therapeutic approaches designed for different stages of Alzheimer's -- The future of therapies targeting amyloid deposition.…”
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Electronic Audio -
13
Abeta toxicity 1
Published 2011Table of Contents: “…Contents: The amyloid plaque -- Impact of delaying onset of AD -- The amyloidocentric theory of Alzheimer's disease -- Compelling evidence for the Abeta theory of AD -- Delay onset of AD by 5 years -- The best target for a disease-modifying drug -- APP structure and domains -- Iron-export ferroxidase activity of beta-amyloid precursor protein -- Age at onset correlates with Abeta isoforms -- Activation of PS1 -- Abeta amyloid -- The mechanism of neurodegeneration -- Abeta metal binding modes -- Current working model of Abeta toxicity -- Abeta amyloid protein: current model consistent with EXAFS -- Metal-protein attenuating compound (MPAC) with moderate affinity for metals -- Clioquinol (CQ, PBT1) the prototypic MPAC -- PBT2: SAR based on rational drug design -- CQ (PBT1) vs. …”
Get full text
Series (Alzheimer disease)
Series (Drug discovery and development in the neurosciences)
Electronic Video -
14
Abeta toxicity 1
Published 2011Table of Contents: “…Contents: The amyloid plaque -- Impact of delaying onset of AD -- The amyloidocentric theory of Alzheimer's disease -- Compelling evidence for the Abeta theory of AD -- Delay onset of AD by 5 years -- The best target for a disease-modifying drug -- APP structure and domains -- Iron-export ferroxidase activity of beta-amyloid precursor protein -- Age at onset correlates with Abeta isoforms -- Activation of PS1 -- Abeta amyloid -- The mechanism of neurodegeneration -- Abeta metal binding modes -- Current working model of Abeta toxicity -- Abeta amyloid protein: current model consistent with EXAFS -- Metal-protein attenuating compound (MPAC) with moderate affinity for metals -- Clioquinol (CQ, PBT1) the prototypic MPAC -- PBT2: SAR based on rational drug design -- CQ (PBT1) vs. …”
Get full text
Series (Alzheimer disease)
Series (Drug discovery and development in the neurosciences)
Electronic Video -
15
Current directions in the prevention and treatment of Alzheimer's disease
Published 2018Table of Contents: “…Contents: Amyloid build-up and the importance of early diagnosis -- The potential of inhibiting vs. clearing amyloid aggregation -- Different potential therapeutic approaches designed for different stages of Alzheimer's -- The future of therapies targeting amyloid deposition.…”
Get full text
Series
Electronic Audio -
16
Current directions in the prevention and treatment of Alzheimer's disease
Published 2018Table of Contents: “…Contents: Amyloid build-up and the importance of early diagnosis -- The potential of inhibiting vs. clearing amyloid aggregation -- Different potential therapeutic approaches designed for different stages of Alzheimer's -- The future of therapies targeting amyloid deposition.…”
Get full text
Series
Electronic Audio -
17
Targeting Aß oligomers a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease /
Published 2014Table of Contents: “…Contents: The oligomer cascade hypothesis for Alzheimer's Disease -- Why the oligomer hypothesis has largely supplanted the amyloid cascade hypothesis -- The role of AβOs in memory failure and the major facets of AD neuropathology -- Mechanisms by which AβOs instigate neurotoxicity -- Why AβOs accumulate in the first place -- How AβOs offer superb targets for novel AD diagnostics and disease-modifying therapeutics -- Beside its direct link to Alzheimer's disease, the discovery of toxic Aβ oligomers has provided a novel structural archetype for toxins germane to more than two dozen diseases of protein mis-folding, including Diabetes, Parkinson's, and prion diseases.…”
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Series
Electronic Video -
18
Targeting Aß oligomers a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease /
Published 2014Table of Contents: “…Contents: The oligomer cascade hypothesis for Alzheimer's Disease -- Why the oligomer hypothesis has largely supplanted the amyloid cascade hypothesis -- The role of AβOs in memory failure and the major facets of AD neuropathology -- Mechanisms by which AβOs instigate neurotoxicity -- Why AβOs accumulate in the first place -- How AβOs offer superb targets for novel AD diagnostics and disease-modifying therapeutics -- Beside its direct link to Alzheimer's disease, the discovery of toxic Aβ oligomers has provided a novel structural archetype for toxins germane to more than two dozen diseases of protein mis-folding, including Diabetes, Parkinson's, and prion diseases.…”
Get full text
Series
Electronic Video -
19
Targeting Aß oligomers a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease /
Published 2014Table of Contents: “…Contents: The oligomer cascade hypothesis for Alzheimer's Disease -- Why the oligomer hypothesis has largely supplanted the amyloid cascade hypothesis -- The role of AβOs in memory failure and the major facets of AD neuropathology -- Mechanisms by which AβOs instigate neurotoxicity -- Why AβOs accumulate in the first place -- How AβOs offer superb targets for novel AD diagnostics and disease-modifying therapeutics -- Beside its direct link to Alzheimer's disease, the discovery of toxic Aβ oligomers has provided a novel structural archetype for toxins germane to more than two dozen diseases of protein mis-folding, including Diabetes, Parkinson's, and prion diseases.…”
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Series
Electronic Video -
20
Update on fluid biomarkers for neurodegenerative diseases
Published 2022Table of Contents: “…Contents: Fluid biomarker candidates for neurodegenerative disease -- Amyloid pathology -- CSF and plasma/serum NfL -- CSF Aβ42 in Alzheimer's disease and neuroinflammatory diseases -- Tau pathology in Alzheimer's disease -- Neurodegeneration -- CSF and plasma NfL as biomarkers for disease progression -- Drug treatment and NfL levels.…”
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Series (Biomarkers)
Series (Drug discovery and development in the neurosciences)
Series (Genetic basis of neurological disorders)
Electronic Video