Search Results - Models, Genetic.

Statistical models in population genetics

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Creating animal models by genetic techniques

Table of Contents: “…Contents: Choosing the right animal models -- Inserting a transgene into an organism model (random or targeted integration) -- Controlling space and time of transgene expression -- Genome editing via CRISPR-Cas9 -- Examples of genetically engineered models -- Latest developments in genetic engineering.…”
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The genetics of stuttering

Table of Contents: “…Contents: The genetics of stuttering -- Genetics -- Neuroscience -- Speech and language pathology -- Twin and adoption studies -- Medical genetics -- Mice as a model for stuttering.…”
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Graphical modelling of linkage disequilibrium

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Building genetic and environmental marker models to predict exceptional survival

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An introduction to statistics for statistical genetics part 2, models and techniques common in statistical genetics /

Table of Contents: “…Contents: Hidden Markov models -- Imputation and genetic imputation -- Principal Component Analysis (PCA) -- Mixed Models -- Shrinkage and regularisation methods.…”
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Population structure in genome-wide association studies detection and correction /

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Meta-analysis in genome-wide association studies application to type 2 diabetes /

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Statistical tests for association

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Imputing genotypes in genome-wide association studies

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Designing a genome-wide association study

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Genotyping algorithms for genome wide association studies

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Assessing significance in genome-wide studies

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Copy number variation and association studies

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Quality control measures for GWAS

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Deciphering neurodegeneration models and methods /

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Bayesian approaches for modelling complex metabolic pathways

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Genetic drift in human evolution part 2 of 2 /

Table of Contents: “…Contents: Genomic signature of genetic drift on human populations -- Serial founder effect model -- Genetic drift signature on the site frequency spectrum (SFS) -- Future directions.…”
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Animal models to explore cardiovascular disease

Table of Contents: “…Contents: Atherosclerosis is a complex disease involving several different molecular and cellular mechanisms in its pathogenesis -- For its experimental investigation, usually higher animals as mammals need to be employed -- Here, the animal models currently used in atherosclerotic research are reviewed und their respective advantages and disadvantages are depicted -- Use of inbred mouse strains and different genetically modified mice -- The main disparities between mouse and human lipid metabolism -- Considerations and techniques to create useful animal models.…”
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Drosophila as a model for drug addiction

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