Search Results - "nanoparticle"

DNA, not merely the secret of life part 2 of 2 /

Table of Contents: “…Contents: Organizing nanoparticles with DNA -- Nanomechanical devices and walkers -- A DNA-based assembly line -- Devices and states that change state in 3D.…”
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Protoporphyrin IX (PpIX)-conjugated self-lighting nanoparticles for photodynamic therapy synthesis and characterization /

Table of Contents: “…Contents: Photodynamic therapy (PDT) mechanism of action -- PDT & photosensitizer Protoporphyrin IX (PpIX) -- After Glow NanoParticles (AG NPs) -- Solving low solubility of PpIX -- Conjugation of PpIX to AG NPs -- In vitro study: cell viability, cancer cells and UV treatment.…”
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Vaginal and uterine drug delivery

Table of Contents: “…Contents: Overview of the anatomy and physiology of the vagina -- Features of the vaginal and uterine routes of drug administration -- Barriers to vaginal drug delivery -- The need for drug delivery systems to the vaginal and uterine routes -- Update on recent advances in the formulation of drug nanosystems for vaginal delivery -- Materials used for developing drug delivery systems -- Nanocarriers for vaginal drug delivery: nanoparticles, liposomes, nanoemulsions, dendrimers, and cyclodextrins.…”
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Nanomedicine promises and pitfalls, part 2 of 3 /

Table of Contents: “…Contents: Simultaneous ways to detect & kill bacteria -- Determining biofilm and bone formation -- Implantable sensor and drug administration -- Carbon nanofibers/nanotubes for neural implants -- Drug delivery on demand -- Stem cells & carbon nanofibers as treatment -- Nanomedicine pitfalls -- Nanoparticle toxicity -- Silver nanoparticles.…”
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Nanotechnology for intracellular nucleic acid delivery

Table of Contents: “…Contents: Using nucleic acids as therapeutics -- Nucleic acid delivery systems -- Nucleosome mimicking polymer particles -- Cationic shell-crosslinked knedel-like nanoparticles (cSCKs) -- High density spherical nucleic acids (SNAs) -- Hollow SNAs.…”
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Increasing tumor targeting efficacy by nanomedicine

Table of Contents: “…Contents: Rationale: low target efficacy drugs -- Physiochemical properties of nanoparticles -- Mesenchymal stem cell-nanodrug delivery -- Transportation to cancer organelles.…”
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DNA, not merely the secret of life part 1 of 2 /

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Inorganic porous drug delivery carriers

Table of Contents: “…Contents: Drug delivery systems -- Advantages and characteristics of porous materials -- Mesoporous silica nanoparticles (MSNs) -- Material design aspects for drug delivery efficacy -- Formulation aspects to be considered -- Examples of in vitro cellular targeting -- In vivo therapeutic delivery and detection.…”
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Need for drug delivery systems part 1 /

Table of Contents: “…Contents: Conventional pharmaceutical dosage forms -- Strategies to improve drug bioavailability -- Liposomes -- Micelles -- Nanoemulsions -- Microemulsions -- Nanoparticles -- Polymeric and lipidic nanoparticles -- Dendrimers -- Limitations of nanosystems.…”
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Drug delivery for cancer therapeutics

Table of Contents: “…Contents: Cancer therapeutics -- Drug delivery mechanisms -- Drug development -- Liposomes -- Nanoparticles -- Nanotechnology -- Nanotoxicology -- Niosomes -- Dendrimers -- Micelles -- Routes of drug delivery.…”
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Vaccine adjuvants part 1 of 2 /

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Nanotechnology in cancer and insulin therapy

Table of Contents: “…Contents: Nanotechnology -- Cancer therapy -- Insulin therapy -- Nanoparticles -- Polymer chemistry -- Drug design -- Coated vs. uncoated drugs -- Controlled drug delivery.…”
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Therapeutic delivery of RNAi

Table of Contents: “…Contents: RNAi therapeutics development -- RNAi cellular activity -- In vivo siRNA delivery is key -- Clinically viable siRNA deliveries -- Local delivery of siRNA -- Gene silencing in tumors -- Cancer target validation in vivo -- RNAi effects in mouse brain, joints, eyes and lungs -- siRNA therapeutics in primate models -- Challenges to siRNA systemic delivery -- Systemic delivery technology -- Targeted nanoparticle siRNA delivery -- Self assembled nanoparticle -- Integrin av-beta is a validated target -- Dual-targeted therapeutic approach -- Neovasculature targeting siRNA -- Multi-targeted anti-angiogenesis -- Efficient targeted systemic delivery -- Systemic siRNA delivery to eyes -- Systemic siRNA delivery for neuroblastoma treatment -- Tumor neovasculature inhibition -- siRNA/Atelocollagen anti-tumor efficacy -- Transferrin-mediated systemic delivery -- Antibody-mediated tumor targeting -- Targeted anti-HBV activity -- RNAi effect of chol-siRNA -- PEI-mediated siRNA lung targeting -- Clinicallyviable delivery is the key for successful siRNA therapeutics.…”
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Polymers as nanocarriers for controlled drug delivery

Table of Contents: “…Contents: Definition and introduction of polymers as nanocarriers -- Mechanisms and triggers for controlled drug delivery -- Biological fate of polymeric nanocarriers -- The use of polymer-drug conjugates for anticancer therapy -- Examples of thermoresponsive nanogels and polymeric nanoparticles for hair follicle penetration for topical drug delivery.…”
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Systemic RNA interference (RNAi) therapeutics for the treatment of HIV-1

Table of Contents: “…-- Major goals of anti-HIV therapies -- Combinatorial RNA based therapy for HIV -- Applying RNAi for the treatment of human diseases -- treat HIV infection by systemic delivery of small RNAs -- Aptamers -- Chimeric-siRNA aptamer uptake into gp120 expressing cells -- Aptamer-targeted RNA interference for HIV-1 therapy -- Aptamer and aptamer chimera mediated inhibition of HIV-1 -- Small animal model for studying anti-HIV RNAi based therapies -- Both aptamer and aptamer chimera inhibit HIV infection -Aptamer and chimeric aptamer-siRNA prevent CD4+ cell decline -- Aptamer and dsiRNAS effect on viral load -- Flexible PAMAM dendrimers with a triethanolamine core -- Dendrimers plus siRNAs form nanoparticles, protect siRNA from degradation and deliver siRNAs to T-lymphocytes -- G5 dendrimer delivered siRNAs down regulate target mRNAs in vitro -- Multiplex siRNAs for HIV-1 treatment -- In vivo analyses of G5 dendrimer delivered siRNAs -- Reductions in HIV loads following dendrimer siRNA injections -- Dendrimer-siRNA complexes protect HIV infected RAG-hu mice from CD4 T cell loss -- Bio distribution of G5 dendrimer siRNAs.…”
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