Search Results - "chaperonin"
Suggested Topics within your search.
Suggested Topics within your search.
- Molecular Chaperones 12
- Protein Folding 8
- Molecular chaperones 7
- Protein folding 6
- Chaperonin 60 5
- metabolism 5
- Chaperonin 10 4
- Chaperonins 4
- Chaperonin Containing TCP-1 2
- Protein Conformation 2
- Proteins 2
- chemistry 2
- Actins 1
- Adenosine Triphosphate 1
- Allosteric Regulation 1
- Cancer 1
- Causes and theories of causation 1
- Cytosol 1
- Diseases 1
- Etiology 1
- Eukaryotic Cells 1
- HSP70 Heat-Shock Proteins 1
- HSP90 Heat-Shock Proteins 1
- Heat-Shock Proteins 1
- Macromolecular Substances 1
- Molecular biology 1
- Neoplasms 1
- Protein Structure 1
- Saccharomyces cerevisiae 1
- adverse effects 1
-
1
The roles of chaperonins in bacteria
Published 2007Table of Contents: “…Contents: The discovery of the GroEL chaperonin in E. coli -- Organization of the GroEL and GroES genes -- Oligomeric structure of GroEL and GroES proteins -- Key roles of GroEL -- The substrates of GroEL -- Chaperonins in other bacteria and their roles.…”
Get full text
Series
Electronic Video -
2
Mitochondrial chaperonin Hsp60 locations, functions and pathology /
Published 2021Table of Contents: “…Contents: Chaperonology: the study of molecular chaperones in all their aspects, normal and pathological -- The chaperoning system: the entire complement of chaperones in an organism, including co-chaperones and co-factors -- Chaperonopathies: diseases in which abnormal chaperones play a pathogenic role -- Hsp60: the mitochondrial chaperonin Cpn60 -- Genetic Hsp60 chaperonopathies: pathologic conditions in which Hsp60 mutations are involved as etiologic-pathogenic factors -- Hsp60 in cancer: Hsp60 chaperonopathies by mistake, in which the chaperonin helps the tumour rather than the patient.…”
Get full text
Series
Electronic Video -
3
Chaperonin-mediated protein folding part 1 /
Published 2012Table of Contents: “…Contents: Chaperonin-mediated protein folding by GroEL/GroES -- Folding of newly-translated protein -- Currently known Molecular chaperones (including the Heat shock protein Hsp group) -- Recognition of non native proteins by Hsps and formation of aggregates -- Aggregates and neurodegenerative disease -The discovery of the chaperonin-mediated folding -- The structure of the GroES/GroeEL chaperonin class of molecular chaperones -- The steps of polypeptide binding and folding -- The action of ATP binding and hydrolysis in driving the rings of the machine through cycles of binding and release cycle.…”
Get full text
Electronic Video -
4
Chaperonin-mediated protein folding part 2 /
Published 2012Table of Contents: “…Contents: Chaperonin-mediated protein folding by GroEL/GroES -- Folding of newly-translated protein -- Currently known Molecular chaperones (including the Heat shock protein Hsp group) -- Recognition of non native proteins by Hsps and formation of aggregates -- Aggregates and neurodegenerative disease -The discovery of the chaperonin-mediated folding -- The structure of the GroES/GroeEL chaperonin class of molecular chaperones -- The steps of polypeptide binding and folding -- The action of ATP binding and hydrolysis in driving the rings of the machine through cycles of binding and release cycle.…”
Get full text
Electronic Video -
5
The interaction network of the GroEL chaperonin
Published 2012Table of Contents: “…-- Identification of the GroEL interaction proteome -- Class III substrates are of relatively low cellular abundance but occupy most of the GroEL capacity -- Chaperonins provide a specialized folding environment with two functional elements: sequestration and steric confinement in a hydrophilic cage -- GroEL as part of the cytosolic chaperone network.…”
Get full text
Series
Electronic Video -
6
Mechanistic aspects of chaperonin GroEL/ES function
Published 2020Table of Contents: “…Contents: Chaperonin structure -- The allosteric mechanism of GroEL coupling between GroEL allostery and folding -- The unfoldase activity of GroEL -- The GroE reaction cycle.…”
Get full text
Series
Electronic Video -
7
Role of chaperonin-like proteins in Bardet-Biedl syndrome
Published 2007Table of Contents: “…Contents: Introduction to chaperonins -- Evolution of chaperonins -- Introduction to Bardet-Biedl syndrome (BBS) and ciliopathies -- Cloning of BBS disease genes -- Role of chaperonins in Bardet-Biedl syndrome.…”
Get full text
Series
Electronic Video -
8
Chaperonin-containing TCP-1 (CCT), actin springs, and protein folding fluxes
Published 2021Table of Contents: “…Contents: Chaperonins -- Chaperonin containing TCP-1 (CCT) -- Evolution of CCT -- Structure of CCT -- Genetic and proteomic analysis of the CCT interactome in S. cerevisiae -- Substrates of CCT -- Proposed energy landscape of actin folding.…”
Get full text
Series
Electronic Video -
9
Overview of eukaryotic molecular chaperones in the cytosol
Published 2020Table of Contents: “…Contents: Protein folding and molecular chaperones -- Hsp70/Hsc70 -- Co-chaperones of Hsc70 -- Chaperonin TRiC/CCT -- Prefoldin -- Hsp90 -- Co-chaperones of Hsp90 -- Specialized co-chaperones -- Heat shock protein chaperones.…”
Get full text
Series
Electronic Video -
10
History of the molecular chaperone concept roles in assembly processes /
Published 2007Table of Contents: “…Contents: Definition of protein self-assembly and aggregation -- First use of the term 'molecular chaperone' -- Nucleoplasmin -- Chloroplast rubisco aggregation -- The chaperonins -- The general chaperone concept -- Definition of 'molecular chaperone' -- The chaperone function -- Protein folding on polysomes -- Macromolecular crowding -- Folding and assembly chaperones -- Nuclear chaperones -- Nucleosome assembly -- Mechanism of nucleoplasmin action -- The rubisco assembly chaperone RbcX.…”
Get full text
Series
Electronic Video -
11
Protein folding inside the cell macromolecular crowding and protein aggregation /
Published 2007Table of Contents: “…Contents: The principle of protein self-assembly -- Discovery of proteins binding to newly synthesized polypeptides -- Discovery of the chaperonins -- Origins of the molecular chaperone concept -- Replacement of spontaneous self-assembly by assisted self-assembly -- Protein aggregation as a universal cellular problem -- Macromolecular crowding and its effects on reaction rates and association constants -- Stimulation of aggregation by crowding -- How chaperones combat aggregation -- Definition of molecular chaperones -- The chaperone function.…”
Get full text
Series
Electronic Video -
12
Chaperone mechanisms in cellular protein folding
Published 2007Table of Contents: “…Contents: The effect of protein aggregation on productive protein folding -- The function of GroEL and GroES as a folding cage for proteins -- Changes in energy landscape within the folding cage -- Cooperation of different chaperone systems in folding pathways: Hsp70 and chaperonins -- Binding of the Hsp70 homologue protein, DnaK, to newly-synthesized polypeptides -- The role of chaperone mechanisms in toxicity suppression of misfolded disease causing proteins -- Potential uses of the chaperone mechanisms in disease therapeutics.…”
Get full text
Series (Molecular chaperones)
Series (Protein folding)
Electronic Video