Search Results - "aryl hydrocarbon receptor"

General factors affecting drug metabolism the role of nuclear receptor superfamily members in induction /

Table of Contents: “…Contents: Drug metabolism and gene transcription - Role of nuclear receptors in drug metabolism induction - Aryl hydrocarbon receptor - Pregnane X receptor - Constitutive androstane receptor - Human examples of drug metabolism induction…”
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Interleukin-6 back to the future /

Table of Contents: “…Contents: IL-6 is a pleiotropic proinflammatory cytokine -- Its overproduction is involved in inflammatory autoimmune diseases including rheumatoid arthritis -- Blocking of IL-6 signals by anti-IL6 receptor antibody (Tocilizumab) shows therapeutic effect on various autoimmune diseases -- Tocilizumab exerts its effect by inhibiting the induction of a helper T cell subset (TH17) -- Aryl-hydrocarbon receptor (Ahr) is one of the essential molecule for the IL-6 mediated induction of TH17 cells.…”
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