Search Results - "NIH"
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Ethical considerations in dealing with CNV information
Published 2010Table of Contents: “…-- Existing guidelines on returning results -- National Bioethics Advisory Commission -- UK Biobank -- NIH guidelines -- Arguments FOR returning CNV results -- Arguments AGAINST returning CNV results -- Avoiding CNV exceptionalism -- What results mean to families -- What we still need to know.…”
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Series
Electronic Video -
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Accelerating drug discovery with machine learning and AI
Published 2022Table of Contents: “…Contents: Machine-learning techniques -- Artificial intelligence methods -- Drug discovery -- Molecular modeling -- Choosing a disease -- Identifying a drug target -- Choosing the bioassay -- AlphaFold 2: Protein structure prediction -- Computer-assisted drug design -- NIH IDG-DREAM -- Predictive vs. generative models -- Molecular design with deep reinforcement learning.…”
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Series
Electronic Video -
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Ethical issues in human population genetics
Published 2021Table of Contents: “…Contents: The ethical issues in human genetics -- ELSI issues -- DNA in establishing identity -- DNA in unveiling the past -- DNA predicts the future -- Manipulation of DNA -- Ownership and control of DNA -- Deeper cultural changes -- Population genetics -- DNA in group history -- The Navajo people -- DNA in group stigma -- DNA in exploitation -- DNA and racism -- DNA and biological warfare -- The consent of a research population -- The NIH alternative for consent -- Control -- Confidentiality -- Return of information -- Benefit sharing.…”
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Electronic Video -
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RAS pathway and disease neurofibromatosis and beyond /
Published 2014Table of Contents: “…Contents: Neurofibromatosis type 1 (NF1) -- NIH diagnostic criteria (Seven criteria for NF1) -- NF1 and the RAS pathway -- NF1 tumour biology -- Neurofibromin deficiency -- Two types of neurofibromas -- Plexiform neurofibroma in the neck and mouth -- Mechanisms of disease -- Mouse models of neurofibroma formation -- Imatinib mesylate treatment -- Clinical aspects of glomus tumours of fingertips -- Gastrointestinal stromal tumours -- MPNST in NF1 -- FDG-PET as a diagnostic tool -- Hotspots for recombination & NF1 microdeletion -- SUZ12-loss -- Cafe-au-lait (CAL) macules -- Skeletal defects in NF1 -- Learning disabilities in NF1 -- Simvastatin treatment for cognitive deficits -- Mosaicism for NF1 mutation -- Diagnostic problems -- SPRED1 mutations & molecular mechanism of Legius syndrome -- The RAS pathway proteins & genetic syndromes (RASopathies).…”
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Series
Electronic Video