Search Results - "Pharmacogenetics"

Pharmacogenetics progress, pitfalls and clinical potential /

Table of Contents: “…Contents: Therapeutic index, genetic variation determining codine and thiopurine metabolism -- Pharmacogenetics and statin response, involvement of HMG co-reductase -- Statin response in patients with FH -- Anti-inflammatory effects of statins and the IL-6 gene -- Pravastatin and CETP genotype -- Initial studies -- Pravastatin and CETP genotype -- Meta-analysis results -- Use of pharmacogenetics to avoid side effects -- Warfarin and CYP2C9 as an example -- Ethical concerns.…”
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Pharmacogenetics

Table of Contents: “…Contents: Definition and history -- CYP2D6 polymorphism -- Pharmacogenetics of warfarin -- Thiopurine methyltransferase -- Genetics susceptibility to adverse drug reactions.…”
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Pharmacogenetics progress, pitfalls and clinical potential /

Table of Contents: “…Contents: Therapeutic index, genetic variation determining codine and thiopurine metabolism -- Pharmacogenetics and statin response, involvement of HMG co-reductase -- Statin response in patients with FH -- Anti-inflammatory effects of statins and the IL-6 gene -- Pravastatin and CETP genotype -- Initial studies -- Pravastatin and CETP genotype -- Meta-analysis results -- Use of pharmacogenetics to avoid side effects -- Warfarin and CYP2C9 as an example -- Ethical concerns.…”
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Pharmacogenetics

Table of Contents: “…Contents: Definition and history -- CYP2D6 polymorphism -- Pharmacogenetics of warfarin -- Thiopurine methyltransferase -- Genetics susceptibility to adverse drug reactions.…”
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Pharmacogenetics and individualized therapy

Table of Contents: “…Pharmacogenetics : a historical perspective / A.K. Daly -- Pharmacogenetics in drug metabolism : role of phase I enzymes / V. …”
An electronic book accessible through the World Wide Web; click to view

Pharmacogenetics of tardive dyskinesia a "Movement" towards individualized therapy. Part I /

Table of Contents: “…Contents: Postulated mechanisms of schizophrenia -- Dopaminergic pathways in schizophrenia -- The Pharmacogenetic paradigm -- Pharmacokineticpharmacodynamic-environmental interactions -- Complex trait genetics -- Antipsychotic adverse reactions -- Tardive dyskinesia -- Postulated mechanisms -- Genetic association studies of TD -- Candidate genes in TD -- Pharmacodynamics and TD: a look at dopaminergic and serotonergic candidates.…”
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Pharmacogenetics of tardive dyskinesia a "Movement" towards individualized therapy. Part II /

Table of Contents: “…Contents: Pharmacokinetics and TD: a look at the cytochrome P450 system -- Oxidative stress and TD: a look at free radicals and the superoxide dismutase genes -- Psychiatric pharmacogenetics as cleaner complex phenotypes -- Neuroimaging in pharmacogenetics: towards even cleaner phenotypes -- Complex traits and new statistical models for looking at multigene interactions with continuous variables -- Recommendations for future studies: bringing pharmacogenetics from "Bench to Bedside" and from "Bedside back to Bench" -- Onward towards individualized pharmacotherapy.…”
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Pharmacogenetics of tardive dyskinesia a "Movement" towards individualized therapy. Part I /

Table of Contents: “…Contents: Postulated mechanisms of schizophrenia -- Dopaminergic pathways in schizophrenia -- The Pharmacogenetic paradigm -- Pharmacokineticpharmacodynamic-environmental interactions -- Complex trait genetics -- Antipsychotic adverse reactions -- Tardive dyskinesia -- Postulated mechanisms -- Genetic association studies of TD -- Candidate genes in TD -- Pharmacodynamics and TD: a look at dopaminergic and serotonergic candidates.…”
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Pharmacogenetics of tardive dyskinesia a "Movement" towards individualized therapy. Part II /

Table of Contents: “…Contents: Pharmacokinetics and TD: a look at the cytochrome P450 system -- Oxidative stress and TD: a look at free radicals and the superoxide dismutase genes -- Psychiatric pharmacogenetics as cleaner complex phenotypes -- Neuroimaging in pharmacogenetics: towards even cleaner phenotypes -- Complex traits and new statistical models for looking at multigene interactions with continuous variables -- Recommendations for future studies: bringing pharmacogenetics from "Bench to Bedside" and from "Bedside back to Bench" -- Onward towards individualized pharmacotherapy.…”
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Pharmacogenetics of psychotropic drugs

Subjects: An electronic book accessible through the World Wide Web; click to view

Pharmacogenetics of breast cancer towards the individualization of therapy /

Subjects: An electronic book accessible through the World Wide Web; click to view

Haplotype-based mapping in pharmacogenetics

Table of Contents: “…Contents: Pharmacogenetics: a simpler complex trait? -- Mapping strategies: map-based and sequence-based -- Tagging SNPs: definition and assessment -- Case study: tagging in 56 drug transport and metabolism genes -- tSNP efficiency: influence of sample size, SNP frequency and SNP density -- Case study: ABCB1 and anti-epileptic drug resistance -- Associated interval.…”
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Haplotype-based mapping in pharmacogenetics

Table of Contents: “…Contents: Pharmacogenetics: a simpler complex trait? -- Mapping strategies: map-based and sequence-based -- Tagging SNPs: definition and assessment -- Case study: tagging in 56 drug transport and metabolism genes -- tSNP efficiency: influence of sample size, SNP frequency and SNP density -- Case study: ABCB1 and anti-epileptic drug resistance -- Associated interval.…”
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Pharmacogenomics in clinical therapeutics

Table of Contents: “…Langman, and Amitava Dasgupta -- Pharmacogenomics aspect of warfarin therapy / Matthew D. Krasowski -- Pharmacogenetics and cancer chemotherapy / Christine L.H. …”
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The politics of personalised medicine pharmacogenetics in the clinic / by Hedgecoe, Adam

Subjects: “…Pharmacogenetics Social aspects.…”
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Genetic determinants of antipsychotic-induced weight gain

Table of Contents: “…Contents: Antipsychotic drugs: limitations and side effects -- Drug-induced weight gain -- Severity and consequences -- Receptor mechanisms -- Role of 5-HT2C receptor -- Pharmacogenetics of antipsychotic weight gain: 5-HT2C promoter polymorphism -- Functional mechanism of polymorphism -- Role of leptin and leptin-promoter polymorphism -- Role of genetic testing -- Future directions.…”
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Rapid methods for the genetic determination of pharmacokinetic status

Table of Contents: “…Contents: Key pharmacogenetic targets -- Minimizing laboratory processing -- Homogenous reactions and DNA probes -- Rapid and simple allele discrimination -- Point of care.…”
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Phase II metabolism

Subjects: “…Pharmacogenetics.…”
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Of genes and drugs genetic determinants of adverse drug reactions /

Table of Contents: “…Contents: Type A and B Adverse Drug Reactions (ADRs) -- Pharmacokineticpharmacodynamic paradigm -- ADME framework -- Mechanisms of ADRs -- Pharmacogenetics and pharmacogenomics -- Polygenic traits -- Environmental factors -- Phenotype and endophenotype -- Candidate genes -- Association and linkage disequilibrium.…”
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Genetic association studies the candidate gene approach /

Subjects: “…Pharmacogenetics.…”
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