Search Results - Study.

In vitro studies and short term studies

Table of Contents: “…Contents: In vitro studies -- Short-term studies -- Acute toxicity studies -- Acute ecotoxicological studies -- Genetic toxicity testing -- Standardized general study plan -- Study-specific supplement -- Standardised final report -- Process-based inspections -- Standard operating procedures -- Test item -- Reference item -- Contamination of batches -- Characterisation of culture media -- Predictive capacity of in-vitro studies -- Assessment of health effects.…”
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Multi-site studies and field studies

Table of Contents: “…Contents: Conduct of multi-site and field studies in compliance with the OECD Principles of GLP -- Context, issues and complexities -- Responsibilities of test facility and test site personnel and sponsor -- Importance of communication -- Master schedule requirements for test sites -- Study plan requirements (with special reference to flexibility required for field studies) -- Performance of the study (with special reference to general facilities and to facilities for handling test and reference items and documentation required for field studies) -- Equipment, control and accountability of study materials for multi-site studies -- Reporting of study results -- Standard Operating Procedures -- Archives.…”
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In vitro studies and short term studies

Table of Contents: “…Contents: In vitro studies -- Short-term studies -- Acute toxicity studies -- Acute ecotoxicological studies -- Genetic toxicity testing -- Standardized general study plan -- Study-specific supplement -- Standardised final report -- Process-based inspections -- Standard operating procedures -- Test item -- Reference item -- Contamination of batches -- Characterisation of culture media -- Predictive capacity of in-vitro studies -- Assessment of health effects.…”
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Series

Multi-site studies and field studies

Table of Contents: “…Contents: Conduct of multi-site and field studies in compliance with the OECD Principles of GLP -- Context, issues and complexities -- Responsibilities of test facility and test site personnel and sponsor -- Importance of communication -- Master schedule requirements for test sites -- Study plan requirements (with special reference to flexibility required for field studies) -- Performance of the study (with special reference to general facilities and to facilities for handling test and reference items and documentation required for field studies) -- Equipment, control and accountability of study materials for multi-site studies -- Reporting of study results -- Standard Operating Procedures -- Archives.…”
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Series

Multi-site studies and field studies

Table of Contents: “…Contents: Conduct of multi-site and field studies in compliance with the OECD Principles of GLP -- Context, issues and complexities -- Responsibilities of test facility and test site personnel and sponsor -- Importance of communication -- Master schedule requirements for test sites -- Study plan requirements (with special reference to flexibility required for field studies) -- Performance of the study (with special reference to general facilities and to facilities for handling test and reference items and documentation required for field studies) -- Equipment, control and accountability of study materials for multi-site studies -- Reporting of study results -- Standard Operating Procedures -- Archives.…”
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Series

In vitro studies and short term studies

Table of Contents: “…Contents: In vitro studies -- Short-term studies -- Acute toxicity studies -- Acute ecotoxicological studies -- Genetic toxicity testing -- Standardized general study plan -- Study-specific supplement -- Standardised final report -- Process-based inspections -- Standard operating procedures -- Test item -- Reference item -- Contamination of batches -- Characterisation of culture media -- Predictive capacity of in-vitro studies -- Assessment of health effects.…”
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Studying aging in humans part 1 of 2, methodology /

Table of Contents: “…Contents: Key issues in studying human aging -- What is human aging -- Organ and tissue changes with aging -- Study approaches, causation and false results.…”
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Studying aging in humans part 2 of 2, Practice /

“…Studying aging in humans. Part 2, Practice…”
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Yeast studies on ageing

Table of Contents: “…Contents: History of studies on yeast ageing -- Senescence factor, molecular memory, and age locus -- Mitochondria and ageing -- Age asymmetry and cell quality control -- Epigenetic gene regulation and ageing -- Genome instability as a cause of ageing -- Replicative and chronological lifespans -- Nutrient effects on lifespan -- Ageing in the wild.…”
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Vaccine preclinical studies part 1 of 2 /

Table of Contents: “…Contents: Introduction to vaccine research -- Goals of preclinical studies -- Preclinical safety for vaccines -- Drug vs. vaccine toxicology -- Basic vaccine toxicology -- Specialized toxicology studies.…”
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Vaccine preclinical studies part 2 of 2 /

Table of Contents: “…Contents: Vaccine pharmacology -- Vaccine immunogenicity -- Vaccine challenge-protection studies.…”
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Reporting of study results

Table of Contents: “…Contents: Definitions and basic principles -- Legal requirements -- Integration of reporting in the whole GLP process -- Responsibilities -- Planning, structure, content and deviations related to reports -- Rejection of studies by the Regulatory Authorities if reports fail.…”
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Genetic association studies the candidate gene approach /

Table of Contents: “…Contents: Background of genetic studies -- Structure of a gene -- Simple association -- Linkage disequilibrium and haplotypes -- Multi-marker association -- Family-based association -- Practicalities of programs and power.…”
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Bioorganic studies of vision

Table of Contents: “…Contents: Visual pigments -- Visual chromophores -- Activation of Rh and beta-AR -- Retinal / vitamin A cycle -- Selective capture of retinoid binding proteins -- Photocrosslinking of chromophore to Rh -- Tracking the chromophore / opsin interaction -- Rhodopsin photocycle -- Photoaffinity labelling -- Chromophore confirmation in Rh -- Transient 'dark activity' of 13-des-Me-retinal -- Retinoids that form pigments -- Photoaffinity study of rhodopsin: G-protein (transducin) interaction -- Age-related macular degeneration -- Age pigments or RPE lipofuscin -- A2E flurophore -- ATP binding cassette protein -- Bilberry extract vs. blue-light induced A2E epoxidation.…”
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Genetic association studies

Table of Contents: “…Contents: Linkage vs. association -- Common variants for common diseases -- Genealogy -- Linkage disequilibrium -- Founder haplotypes -- Genetic heterogeneity -- Hardy Weinberg equilibrium -- Principal component analysis -- Single SNP tests of association for case-control data -- Armitage trend test -- Logistic regression -- Quantitative traits -- Bayesian analyses -- Multiple testing -- Haplotype-based analyses -- Inferring phase -- Problems with haplotype analyses -- Imputation -- Genetic association studies -- Family-based tests of linkage and association -- Software.…”
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Evolutionary case study the genomics of speciation in Heliconius butterflies /

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Studying aging in humans part 1 of 2, methodology /

Table of Contents: “…Contents: Key issues in studying human aging -- What is human aging -- Organ and tissue changes with aging -- Study approaches, causation and false results.…”
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Series

Studying aging in humans part 2 of 2, Practice /

“…Studying aging in humans. Part 2, Practice…”
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Series

Yeast studies on ageing

Table of Contents: “…Contents: History of studies on yeast ageing -- Senescence factor, molecular memory, and age locus -- Mitochondria and ageing -- Age asymmetry and cell quality control -- Epigenetic gene regulation and ageing -- Genome instability as a cause of ageing -- Replicative and chronological lifespans -- Nutrient effects on lifespan -- Ageing in the wild.…”
Get full text
Series

Vaccine preclinical studies part 1 of 2 /

Table of Contents: “…Contents: Introduction to vaccine research -- Goals of preclinical studies -- Preclinical safety for vaccines -- Drug vs. vaccine toxicology -- Basic vaccine toxicology -- Specialized toxicology studies.…”
Get full text
Series