Search Results - Orsinia~

Human pathogenic Yersinia species

Table of Contents: “…Contents: Classification of strains -- Different degrees of pathogenicity -- Intestinal Yersinia infections: transmission and outcomes -- Transmission modes of Y. pestis -- Pneumonic and bubonic plague -- Adhesion and invasion -- Invasin -- Gene expression -- Vacuole trafficking -- Secretion systems.…”
Get full text
Series

Biodefense vaccines

Table of Contents: “…Contents: Category A threats -- Available vaccines -- Smallpox -- Vaccinia: the first vaccine -- Vaccination has risks -- Anthrax -- Vaccines in advanced trials -- Plague as an agent of bioattack -- Response to biodefense needs -- Yersinia pestis pathogenesis -- The F1 capsule -- Type III secretion system -- Immunity to Y. pestis -- Plague vaccines -- Disadvantages of the current approaches -- New plague vaccine approaches -- Subunit vaccines -- Prime-boost strategies -- Innovative approaches to vaccine delivery may provide practical, highly effective protective interventions.…”
Get full text
Series

Virulence plasmids

Table of Contents: “…Contents: Definition and importance of virulence plasmids -- Types of virulence plasmids -- Toxin plasmids -- The anthrax toxin plasmids -- Clostridial toxin plasmids -- Metabolic plasmids -- Mycolactone biosynthesis by Mycobacterium ulcerans -- Iron uptake by Vibrio anguillarum -- Adhesin plasmids -- Enterotoxigenic E. coli: CFA -- Enteropathogenic E. coli: BFP -- Linear plasmids of Borrelia -- Other virulence plasmids -- Shigella: type III secretion system, ipa genes -- Yersinia: type III secretion system, yop genes -- Bacillus anthracis is the causative agent of anthrax -- pXO1 encodes toxin and regulatory genes -- pXO2 encodes capsule and regulatory genes.…”
Get full text
Series

Protein Tyrosine Phosphatases

Table of Contents: “…Contents: Kinases and phosphatases -- Ways to remove phosphate from proteins -- Class I Cys-based PTPs -- Phosphatase families -- Mutational analysis of PTP-1 -- Sequences at active site -- Phospho-enzyme intermediate -- pH stability of phosphoprotein phosphate -- Site-directed mutational analysis of VHR -- How PTPs share a catalytic active site motif -- Sequences of phosphatases -- The bacterial Yop 2b phosphatase activity -- Bacterial growth in the spleen of mice -- Yop 2b in eukaryotic macrophages -- Interaction between Yersinia and a target cell -- Phosphatases as tumor suppressor genes -- PTEN and myotubularin structure -- PTEN-10q23.3 -- Frequency of PTEN mutations -- Kinetic constants of dual-specificity phosphates -- How PTEN is a "lipid" phosphatase -- How PTEN might inhibit cell survival -- Effect of PTEN overexpression on PIP3 production -- Effect of PTEN expression on PI 3-kinase activation -- Inositol phosphatase activity of PTEN -- PTEN tumor suppressor activity -- Key PTEN and PIP3 researchers -RNA interference in C.elegans -- RNA interference protocol for fly S2 cells -- Mammalian, C.elegans and fly signaling cascade -- How PTEN inhibits Akt activity -- The active site pocket of PTEN -- Sequence alignment of PTEN catalytic site.…”
Get full text
Series