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NASH evaluation and treatment /

Table of Contents: “…Contents: NAFLD as a global problem and driver of liver-related burden of disease -- Managing NAFLD in 3 simple steps -- Diagnostic accuracy and performance (CAP) -- Increased risk of mortality by fibrosis stage -- Restoring health for patients with NAFLD -- Key concepts in approach to treatment of NASH -- Various therapeutic options & clinical trials for treatment of NASH.…”
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Advances in the treatment of NASH

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Evolutionary case study the genomics of speciation in Heliconius butterflies /

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Choosing between family-based and population-based association designs

Table of Contents: “…Contents: Population-based association analysis -- Population stratification -- Genomic control -- Structure analysis -- Principal component analysis -- Family-based association analysis -- Parent-of-origin effect -- Genome-wide association analysis -- Combined test using family and population data.…”
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Dose-finding trials in oncology

Table of Contents: “…Contents: Maximum tolerable dose -- Standard or 3+3 design -- A+B designs -- Phase I trials that use toxicity grades -- Escalation versus fixed sample size designs for dose-finding trials -- Continual reassessment method -- Cumulative cohort design -- Start-up rule -- Design modifications for delayed toxicity outcomes -- Trials with two agents and ordered groups.…”
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Family-based association tests FBATs. Part 1, Introduction.

Table of Contents: “…Contents: Definition: genetic association -- Examples -- Linkage disequilibrium -- Case-control analysis -- Samples from mixed populations -- Population admixture -- Dichotomous trait -- The transmission disequilibrium test (TDT) -- An alternative formula for the TDT: FBATs -- FBATs: no parental genotypes -- The general FBAT -- FBATs for quantitative traits.…”
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Family-based association tests FBATs. Part 2, FBATs for various data types /

“…Family-based association tests : FBATs for various data types…”
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Family-based association tests FBATs. Part 3, FBAT testing strategies for large-scale association studies /

Table of Contents: “…Contents: Genome-wide association studies -- Using the same data set for screening and testing -- The conditional mean model -- The FBAT-statistic -- Genetic model under the alternative hypothesis -- The concept of the conditional mean model -- The screening technique for multiple markers -- PBAT's screening techniques for multiple SNPs -- The 3 steps of the screening technique -- The Framingham heart study -- Replication (recessive model) from other studies -- Important observations from Herbert et al. (2006) -- Summary of the approach -- Extensions -- Software implementation.…”
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Cyber-based structure elucidation

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The neural bases of cognitive control

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Fragment-based lead discovery

Table of Contents: “…Contents: Advantages of fragment-based approaches -- Problems and pitfalls -- Methods to find fragments -- Evaluating fragments -- Fragment growing -- Fragment linking -- Summary and resources.…”
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Biofilm based wound care

Table of Contents: “…Contents: Biofilm in nature -- Host biofilm development -- Bacterial biofilm & wound healing -- Molecular mechanisms of senescence -- Planktonic vs. biofilm bacteria -- Medical biofilms -- Biofilm defences -- Antibiotic resistance -- Reconstitution of slough -- The epithelial gap -- Full biofilm debridement -- Acute vs. chronic wound -- Pyoderma to granulation -- Surface management -- Sharp debridement -- Osteomyelitis -- Common skin & skin-structure infection (cSSSI) pathogens -- Clinical identification of bacteria -- Biofilm-based wound care (BBWC) -- Multiple concurrent dynamic strategies -- Personalized wound care -- Negative-pressure wound therapy (NPWT) -- Cell-based therapy (CBT).…”
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COPD treatment case I COPD with "bronchitis attacks" /

Table of Contents: “…Contents: The clinical COPD questionnaire (CCQ) score -- Goals of COPD therapy -- GOLD guideline -- Case management.…”
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COPD treatment case II COPD with asthma as child /

Table of Contents: “…Contents: Asthma-COPD overlap syndrome -- LAMA in asthma -- Case management.…”
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COPD treatment case III COPD with pre-diabetes /

Table of Contents: “…Contents: GOLD guideline -- Metabolic effects of COPD treatment -- Case management.…”
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An introduction to evidence-based medicine

Table of Contents: “…Contents: Making evidence-based clinical decisions -- First principle: nature of Evidence -- Second principle: hierarchies of evidence -- Third principle: values and preferences -- Evidence-based clinicians -- Interpreting the evidence.…”
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Ligand-based drug design

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Structure-based drug design

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Inherited cancer case studies

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