Search Results - BCFM~

Pseudo cluster randomisation

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Pseudo cluster randomisation

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Pseudo cluster randomisation

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The Bcl-2 family

Table of Contents: “…Contents: Apoptosis -- Discovery of Bcl-2 -- Cell death in worms -- Evolutionarily conserved pathways to cell death -- How cell death initiates -- BH3-only proteins -- Control of BH3- only proteins -- Promiscuous and selective BH3-only proteins -- Diverse Bcl-2 prosurvival proteins must be neutralized for apoptosis -- Pro-survival Bcl-2 proteins restrain Bax and Bak -- Apoptosis in the absence of "activator" BH3-only proteins -- BH3-only proteins activate Bax and Bak indirectly -- Control of Bak -- Outstanding questions.…”
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The Bcl-2 family

Table of Contents: “…Contents: Apoptosis -- Discovery of Bcl-2 -- Cell death in worms -- Evolutionarily conserved pathways to cell death -- How cell death initiates -- BH3-only proteins -- Control of BH3- only proteins -- Promiscuous and selective BH3-only proteins -- Diverse Bcl-2 prosurvival proteins must be neutralized for apoptosis -- Pro-survival Bcl-2 proteins restrain Bax and Bak -- Apoptosis in the absence of "activator" BH3-only proteins -- BH3-only proteins activate Bax and Bak indirectly -- Control of Bak -- Outstanding questions.…”
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The Bcl-2 family

Table of Contents: “…Contents: Apoptosis -- Discovery of Bcl-2 -- Cell death in worms -- Evolutionarily conserved pathways to cell death -- How cell death initiates -- BH3-only proteins -- Control of BH3- only proteins -- Promiscuous and selective BH3-only proteins -- Diverse Bcl-2 prosurvival proteins must be neutralized for apoptosis -- Pro-survival Bcl-2 proteins restrain Bax and Bak -- Apoptosis in the absence of "activator" BH3-only proteins -- BH3-only proteins activate Bax and Bak indirectly -- Control of Bak -- Outstanding questions.…”
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The pCF10-encoded pheromone response cell-cell signaling, complexity and evolution /

Table of Contents: “…Contents: Overview of the evolutionary and medical significance of plasmids in E faecalis -- Overview of cell-cell signaling and plasmid transfer -- The sex pheromone system -- Pheromone production and control plasmid pCF10 as a model for pheromone-controlled plasmid transfer -- Mechanism of pheromone induction -- Multiple roles for pheromone induction -- Maintenance of complexity in evolution.…”
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The pCF10-encoded pheromone response cell-cell signaling, complexity and evolution /

Table of Contents: “…Contents: Overview of the evolutionary and medical significance of plasmids in E faecalis -- Overview of cell-cell signaling and plasmid transfer -- The sex pheromone system -- Pheromone production and control plasmid pCF10 as a model for pheromone-controlled plasmid transfer -- Mechanism of pheromone induction -- Multiple roles for pheromone induction -- Maintenance of complexity in evolution.…”
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The pCF10-encoded pheromone response cell-cell signaling, complexity and evolution /

Table of Contents: “…Contents: Overview of the evolutionary and medical significance of plasmids in E faecalis -- Overview of cell-cell signaling and plasmid transfer -- The sex pheromone system -- Pheromone production and control plasmid pCF10 as a model for pheromone-controlled plasmid transfer -- Mechanism of pheromone induction -- Multiple roles for pheromone induction -- Maintenance of complexity in evolution.…”
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Developing tuberculosis vaccines challenges and strategies, part 1 of 2 /

Table of Contents: “…Contents: M. tuberculosis exposure and infection -- Tuberculosis (TB) disease -- Antimicrobial Mtb resistance -- The BCG vaccine -- Challenges of the TB vaccine field -- Potential new & better vaccines -- The variety of Mtb antigens.…”
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CML genetic paradigm of targeted therapy, part 1 of 2 /

Table of Contents: “…Contents: Typical clinical findings and phases of chronic myeloid leukaemia (CML) -- Philadelphia chromosome (juxtaposition & genomic anatomy BCR-ABL1) -- Target cells for transformation -- Molecular driver for pathogenesis (BCR-ABL1 tyrosine kinase) -- Imatinib (inhibitor of BCR-ABL1).…”
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Developing tuberculosis vaccines challenges and strategies, part 1 of 2 /

Table of Contents: “…Contents: M. tuberculosis exposure and infection -- Tuberculosis (TB) disease -- Antimicrobial Mtb resistance -- The BCG vaccine -- Challenges of the TB vaccine field -- Potential new & better vaccines -- The variety of Mtb antigens.…”
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Developing tuberculosis vaccines challenges and strategies, part 1 of 2 /

Table of Contents: “…Contents: M. tuberculosis exposure and infection -- Tuberculosis (TB) disease -- Antimicrobial Mtb resistance -- The BCG vaccine -- Challenges of the TB vaccine field -- Potential new & better vaccines -- The variety of Mtb antigens.…”
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Chromosome translocations and cancer

Subjects: “…Leukemia, Myelogenous, Chronic, BCR-ABL Positive drug therapy.…”
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CML genetic paradigm of targeted therapy, part 2 of 2 /

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CML genetic paradigm of targeted therapy, part 1 of 2 /

Table of Contents: “…Contents: Typical clinical findings and phases of chronic myeloid leukaemia (CML) -- Philadelphia chromosome (juxtaposition & genomic anatomy BCR-ABL1) -- Target cells for transformation -- Molecular driver for pathogenesis (BCR-ABL1 tyrosine kinase) -- Imatinib (inhibitor of BCR-ABL1).…”
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CML genetic paradigm of targeted therapy, part 1 of 2 /

Table of Contents: “…Contents: Typical clinical findings and phases of chronic myeloid leukaemia (CML) -- Philadelphia chromosome (juxtaposition & genomic anatomy BCR-ABL1) -- Target cells for transformation -- Molecular driver for pathogenesis (BCR-ABL1 tyrosine kinase) -- Imatinib (inhibitor of BCR-ABL1).…”
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Global progress in TB vaccine development

Table of Contents: “…Contents: Review of the current vaccine, BCG -- Potential reasons for variability -- Leading approaches to developing a new TB vaccine -- Clinical development of MVA85A.…”
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Chromosome translocations and cancer

Subjects: “…Leukemia, Myelogenous, Chronic, BCR-ABL Positive drug therapy. 100650…”
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CML genetic paradigm of targeted therapy, part 2 of 2 /

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