Search Results - "vaccination"

Vaccines a health insurance of the 21st Century /

Table of Contents: “…Contents: Major health challenges of the 21st Century -- Causes of increased life expectancy: conquest of infectious diseases -- Life expectancy is growing beyond prediction -- New technologies in the last 30 years -- Safety of vaccines -- Meningococcal disease -- Vaccines for Meningococcus C -- Meningococcus B -- Reverse vaccinology allows us to target many pathogens that were difficult or impossible before -- Prevention of cancers -- Vaccination and our aging society -- H5N1 vaccine -- Vaccines to address poverty -- Novartis Vaccines Institute for Global Health.…”
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Vaccination

Table of Contents: “…Contents: The history of vaccination -- Mechanisms of vaccine action -- Types of vaccine -- Vaccine development process -- Vaccine platforms -- Vaccine adjuvants -- Pre-clinical and clinical testing of vaccine candidates.…”
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Biodefense vaccines

Table of Contents: “…Contents: Category A threats -- Available vaccines -- Smallpox -- Vaccinia: the first vaccine -- Vaccination has risks -- Anthrax -- Vaccines in advanced trials -- Plague as an agent of bioattack -- Response to biodefense needs -- Yersinia pestis pathogenesis -- The F1 capsule -- Type III secretion system -- Immunity to Y. pestis -- Plague vaccines -- Disadvantages of the current approaches -- New plague vaccine approaches -- Subunit vaccines -- Prime-boost strategies -- Innovative approaches to vaccine delivery may provide practical, highly effective protective interventions.…”
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History of vaccines

Table of Contents: “…Contents: History of vaccines -- The impact of vaccination -- Variolation -- Pasteur and first real vaccines -- Inactivated vaccines at the end of the 19th Century -- Toxoids -- Attenuation by serial passage -- Viruses grown in cell culture -- Genetic engineering and recombinant vaccines -- Vaccines licensed since 2000 -- Cumulative number of vaccines developed.…”
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Vaccine manufacturing part 1 of 2 /

Table of Contents: “…Contents: The vaccine ecosystem -- How to make a vaccine (brief outline) -- Vaccine antigens -- Assessing vaccine quantities -- Technology & knowledge transfer -- Process development and scaling-up.…”
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Cancer vaccines part 1 of 2 /

Table of Contents: “…Contents: The hallmarks of cancer -- Categories of cancer-associated antigens -- Viral & non-viral cancers: vaccine targets -- Immunotherapeutics -- Immunologic reagents approved for cancer therapy -- Clinical outcome based on immune response -- CTL-based therapy -- Virus-specific CTL adoptive transfer therapy -- Immunotherapy for Melanoma.…”
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Series (Vaccines)

Vaccine adjuvants part 1 of 2 /

Table of Contents: “…Contents: Overview of vaccine adjuvants -- First generation particles -- Alum adjuvants -- MF59 adjuvant -- Polylactide co-glycolide particles.…”
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Cancer vaccines part 2 of 2 /

Table of Contents: “…Contents: HPV infection & prevention strategies -- Global cervical cancer prevalence -- HPV induced lesions & cancers -- Cell-mediated immune response to HPV -- Synthetic Long Peptide (SLP) vaccine concept -- Vulval intraepithelial neoplasia (VIN) vaccine -- Combining chemotherapy & SLP vaccination.…”
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Vaccine manufacturing part 2 of 2 /

Table of Contents: “…Contents: New vaccines & the need for up-to-date technology -- Considerations for manufacturing facilities -- Quality systems (The mechanism for regulatory compliance) -- Large scale, routine manufacturing -- Warehousing and distribution of vaccine product.…”
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Vaccine adjuvants part 2 of 2 /

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Vaccine delivery

Table of Contents: “…Contents: Introduction to immunization (prophylactic vaccines) -- Vaccine formulation -- Types of antigens -- Vaccine delivery routes (parenteral, mucosal, cutaneous) -- Vaccine delivery systems (needle and syringe, needle-free systems) -- Vaccine adjuvants (history, classification, mechanism of action) -- Adjuvants approved with the product -- Edible plant-based vaccines and therapeutic vaccines.…”
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Animal vaccines basic principles /

Table of Contents: “…Contents: Passive immunization -- Active immunization -- Inactivated vaccines -- Living vaccines -- DNA plasmid vaccines -- Adjuvants.…”
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Animal vaccines failures and adverse events /

Table of Contents: “…Contents: Causes of vaccine failure -- Immune responses to vaccines -- Effect of maternal immunity -- Adverse events -- Effect of dog size on immune responses and adverse events -- Type 1, 2 and 3 hypersensitivity reactions.…”
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The past, present and future of vaccination

Table of Contents: “…Contents: History of vaccines, with four lessons of vaccinology -- New vaccines, including those against rotavirus, influenza, zoster and human papillomaviruses -- New strategies of vaccine development, including recombinants, vectors, plasmid DNA and non-parenteral routes of administration.…”
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HIV preventative vaccines

Table of Contents: “…Contents: HIV distribution -- HIV in Africa -- HIV particle -- T-cell responses -- CD4 T-cells susceptible to HIV infection -- CD8 T-cells control HIV infection -- Acute HIV infection -- HIV escape mutations when CTL response focused on dominant epitope -- Immune control of HIV -- Antibody response to HIV-1 -- Viral membrane fusion -- 5 broadly neutralizing antibodies -- Antibody vaccines for HIV -- T-cell vaccine control of HIV -- CD8+ T-cell inducing vaccines partly protect against SIV/SHIV challenge -- HIVA DNA/MVA immunization in mice and macaques -- HIVA DNA + MVA in humans -- MVA.HIVA boosts HIV-1-specific CD8 T-cells in HIV+ donors on ART -- Current T-cell vaccines for HIV -- Phase IIB trials -- Merck rAd5 vaccine -- The problem of HIV variability -- Ways to tackle HIV-1 diversity.…”
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Vaccines in the modern world

Table of Contents: “…Contents: What are vaccines? -- Vaccine composition -- Vaccines in common use -- Type of immune response induced by vaccination -- Impact on disease incidence -- Smallpox: the first vaccine -- Vaccines against polio and meningitis -- What is a conjugated vaccine -- Reverse vaccinology -- Novartis MenB protein vaccine -- Vaccines can now be based on DNA.…”
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Antivirals versus vaccines

Table of Contents: “…Contents: Emerging infections in the past decades -- Human respiratory viruses -- The AIDS pandemic -- HIV vaccine approaches -- Antivirals use against HIV -- Morbilliviruses -- Metapneumovirus -- hMPV -- SARS-CoV -- Candidate SARS vaccines -- Vaccination of macaques against SARS -- Henipahvirus -- Smallpox -- History of smallpox vaccination -- Antiviral drugs against smallpox -- Cidofovir -- Human influenza: three appearances -- Avian influenza A virus: adaptation -- H1N1 virus: relevant mutations -- The Mexican flu virus -- Pre-pandemic H5N1 clinical trials -- The importance of an adjuvant -- Seasonal vaccine and pandemic A/H1N1 -- Flu drugs targets.…”
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RSV vaccine development

Table of Contents: “…Contents: Many obstacles hinder RSV vaccine development -- Disease at extremes of age -- History of disease potentiation with formalin-inactivated RSV vaccine -- Various strategies for vaccine development -- RSV F subunit vaccine -- Maternal immunization -- Immunization of the elderly -- Live-attenuated and/or live-vectored vaccines -- Immunization of infants and children.…”
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The future of influenza vaccines

Table of Contents: “…Contents: Influenza virion structure -- Available flu vaccines -- Problems with current inactivated vaccines -- Live attenuated vaccines -- Subunit vaccine -- New, recently licensed vaccines -- Flu vaccines in development -- Experimental vaccines -- Issues with pandemic vaccines -- Universal influenza vaccines -- The HA protein.…”
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Dengue vaccine development l. Status /

Table of Contents: “…Contents: Scope of the dengue problem -- Assessing the need for a tetravalent vaccine -- In-depth look at current vaccines and their development status.…”
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