Search Results - "survivalism"

Survival analysis

Table of Contents: “…Contents: Censoring -- Truncation -- Survival probability -- Failure probability -- Probability Density Function -- Hazard function -- Cumulative Hazard Function -- Kaplan Meier -- Semi-parametric -- Nelson-Aalen Estimator -- Log rank test -- Selection Bias -- Frailty models -- Competing risk.…”
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Building genetic and environmental marker models to predict exceptional survival

Table of Contents: “…Contents: Genetic component of survival past 100 -- Impact of 100s of genes -- Combinations of variations -- Number of signatures associated with survival to extreme old age.…”
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Rights of passage : four stories of survival /

Immunological memory part 2 of 2 /

Table of Contents: “…Contents: Quantity and quality memory maintenance -- Memory cell survival and homeostasis -- Concept of resource "niches" for survival -- A role for antigen in memory longevity -- Memory and protective immunity.…”
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Factors influencing outcomes in clinical transplantation 1

Table of Contents: “…Contents: Clinical transplantation -- Immunosuppressive drugs -- Long-term graft survival -- Immune responses to transplants -- Rejection -- Alloantibodies -- Antibody-mediated rejection (AMR) -- Hyperacute rejection -- Technology available for detecting and specifying HLA and non-HLA antibodies -- B cells and transplant rejection.…”
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Lineage decisions in the thymus part 1 of 2, T cell lineage commitment /

Table of Contents: “…-- Notch in T cell development -- Gata3 in T cell development -- IL-7(R) for T cell survival.…”
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Protoporphyrin IX (PpIX)-conjugated self-lighting nanoparticles for photodynamic therapy synthesis and characterization /

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Factors influencing outcomes in clinical transplantation 2

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Monoclonal antibodies to induce therapeutic immunological tolerance

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The transcription factor NF-Kappa B an evolutionarily conserved mediator of immune and inflammatory responses /

Table of Contents: “…Contents: NF-kappa B activation and function -- Signal transduction pathway -- Mechanism of post-transcriptional induction -- Gene activation -- Role of NF-kappa B in physiological processes -- Initiation of the immune system -- Cell survival.…”
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Selenium and male fertility

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EGFR inhibitors in NSCLC and the role of biomarkers for selection of patients

Table of Contents: “…Contents: USAEGFR TKIs in 2nd /3rd line therapy -- Phase II activity of EGFR TKIs in unselected NSCLC -- BR.21 study design and overall survival -- Forest plot of survival by subsets -- Is there a survival advantage for male smokers with squamous-cell carcinoma? …”
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Possible roles of mitochondrial biogenesis in aging

Table of Contents: “…Contents: Oxidative phosphorylation -- The mitochondrial DNA -- Aging as the accumulation of damage -- Types of aging damage -- Types of damaged cells -- Survival of cells lacking oxidative phosphorylation -- The plasma membrane redox system -- Reductive hotspot hypothesis -- "Survival of the slowest" hypothesis -- Allotopic expression -- Hydrophobicity prevents allotopic expression of mitochondrially-encoded proteins -- Ways to make these proteins allotopically expressible.…”
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Update on therapies for metastatic melanoma

Table of Contents: “…Contents: Overview of new treatments approved for advanced melanoma in the past few years -- Pegylated interferon alfa-2b -- Ipilimumab -- Mechanism of action -- Impact on progression-free and overall survival -- Overview of immune-related adverse events -- Vemurafenib -- Mechanism of action -- Impact on progression-free and overall survival -- Induction of secondary squamous cell carcinomas -- Possible role for combined RAF/MEK inhibition -- A "standard" approach to treatment of stage IV melanoma.…”
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Phase II trials

Table of Contents: “…Contents: Clinical trial endpoints -- Response rate -- Progression-free survival -- Phase II trial designs -- Randomized phase II -- Enrichment -- Basket and umbrella trials.…”
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Advances in treatment of gliomas

Table of Contents: “…Contents: Burden of disease and survival -- Pathological grading and molecular genetics -- Low-grade gliomas: controversies in treatment -- High-grade gliomas: advances and limitations in current therapies -- Future directions.…”
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An approach to giant cell arteritis (GCA)

Table of Contents: “…Contents: Pathogenesis of GCA -- Common presenting features -- Role of biopsy and diagnostic imaging studies -- Review of available therapies, including steroid-sparing options -- Survival and risk of end-organ damage.…”
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The molecular basis of bacterial pathogenicity an overview /

Table of Contents: “…Contents: Overview of bacterial diseases and virulence factors -- Toxins -- Adherence mechanisms -- Type III secretion systems -- Intracellular survival mechanisms -- Avoiding the immune system -- Impact of microbiota -- Antibiotics -- Vaccines -- Bioterrorism.…”
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The pathology of chronic obstructive pulmonary disease

Table of Contents: “…Contents: Progressive airflow limitation in COPD -- Effect of small airway occlusion on survival -- Methods of assessing lung structure -- The role of the innate and adaptive immune systems in COPD -- Bronchiolar destruction -- Airway remodeling.…”
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Chromosome translocations and cancer

Table of Contents: “…Contents: Chromosome translocations -- Fusion genes in cancer -- Chromosome aberrations in cancer -- Clinical significance of findings -- Prognostic significance -- Imatinib targeted treatment in CML -- Survival of CML patients -- From discovery to targeted treatment.…”
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