Search Results - "model organism"

Developmental biology

Table of Contents: “…Contents: Overview of development biology and its history -- Model organisms in the developmental biology landscape -- Identification of genes in model organisms controlling the body plan -- Developmental biology and clinical genetics -- Human developmental genetics and cellular processes -- Differential gene expression and pattern formation -- Morphogens and the polarizing region in limb development -- Environmental agents that affect limb development.…”
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Introduction to research strategies in cell biology

Table of Contents: “…Contents: Genetic model organisms -- Light microscopy -- Fluorescence microscopy -- Structure determination -- Identification of molecular partners -- Genome engineering -- Testing mathematical modeling.…”
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Fetal macrophages

Table of Contents: “…Contents: The history of studying of macrophages -- The benefits of the various model organisms for studying macrophages; zebrafish, mice, drosophila and C. elegans -- The primary function of embryonic macrophages is to clear away apoptotic cell debris.…”
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Biodemography

Table of Contents: “…Contents: Biodemography of lifespan: concepts, lifespan and sociality, and human lifespan evolution -- Population biology of the elderly: role of elderly in nature & emphasis on social species -- Experimental biodemography of aging: studies in model organisms.…”
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Deciphering neurodegeneration models and methods /

Table of Contents: “…Contents: Deciphering Neurodegeneration: Models and Methods -- The challenge of neurodegeneration -- Huge diversity in cell types -- Nature versus nurture -- Reductionism versus systems biology -- Cellular models -- Yeast -- Primary cells -- Cell lines -- Stem cells -- Model organisms -- Caenorhabditis elegans -- Drosophila melanogaster -- Zebrafish -- Danio rerio -- Rodents -- Molecular biology approaches -- Knock out and knock in -- Genomic editing -- RNAi -- Overexpression -- Gene expression -- rtPCR -- Microarrays -- RNAseq -- Protein analysis -- Immunoblot -- ELISA -- Mass spec and proteomics -- Microscopy -- Immunocytochemistry -- Live cell imaging -- Electrophysiology.…”
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Phagocytosis in the fruit fly, Drosophila melanogaster

Table of Contents: “…Contents: Infectious diseases remain the commonest cause of premature mortality worldwide -- The emergence of antibiotic resistant strains and the risks of bioterrorism have reinforced the importance of understanding the host-pathogen dynamic - It is hopeful that identifying the natural mechanisms used by the host to control infection will provide new avenues for therapeutic intervention -- Model organisms such as Drosophila provide well-characterized, conserved and genetically tractable systems for exploring this dynamic -- Drosophila are amenable to not only forward and reverse genetics but also hold great promise for small molecule screening and other unbiased approaches that will uncover evolutionarily conserved components of the innate immune system.…”
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