Search Results - "metastasis"

Genetics of tumor metastasis part 1 of 2 /

Table of Contents: “…Contents: Understanding carcinoma invasion and metastasis -- Epithelial-mesenchymal transition (EMT) -- Heterotypic signals in tumor growth and progression -- EMT-inducing transcription factors -- Transgenic model of breast cancer pathogenesis.…”
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Genetics of tumor metastasis part 2 of 2 /

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Metastasis of Drosophila tumors

Table of Contents: “…Contents: Recessive lethal mutations of Drosophila cause brain tumors that are metastatic -- Despite their apparent similarities, tumors caused by different mutations have different metastatic properties -- The metastasis of tumors caused by lgl mutations is enhanced by secretion of MMP1 from the tumor cells themselves -- The metastasis of tumors caused by brat mutations is not enhanced by secretion of MMP1 from the tumor cells themselves, but is enhanced by MMP1 that host cells are induced to secrete.…”
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Genetics of tumor metastasis part 1 of 2 /

Table of Contents: “…Contents: Understanding carcinoma invasion and metastasis -- Epithelial-mesenchymal transition (EMT) -- Heterotypic signals in tumor growth and progression -- EMT-inducing transcription factors -- Transgenic model of breast cancer pathogenesis.…”
Get full text
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Genetics of tumor metastasis part 2 of 2 /

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Metastasis of Drosophila tumors

Table of Contents: “…Contents: Recessive lethal mutations of Drosophila cause brain tumors that are metastatic -- Despite their apparent similarities, tumors caused by different mutations have different metastatic properties -- The metastasis of tumors caused by lgl mutations is enhanced by secretion of MMP1 from the tumor cells themselves -- The metastasis of tumors caused by brat mutations is not enhanced by secretion of MMP1 from the tumor cells themselves, but is enhanced by MMP1 that host cells are induced to secrete.…”
Get full text
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Metastasis of Drosophila tumors

Table of Contents: “…Contents: Recessive lethal mutations of Drosophila cause brain tumors that are metastatic -- Despite their apparent similarities, tumors caused by different mutations have different metastatic properties -- The metastasis of tumors caused by lgl mutations is enhanced by secretion of MMP1 from the tumor cells themselves -- The metastasis of tumors caused by brat mutations is not enhanced by secretion of MMP1 from the tumor cells themselves, but is enhanced by MMP1 that host cells are induced to secrete.…”
Get full text
Series

Genetics of tumor metastasis part 1 of 2 /

Table of Contents: “…Contents: Understanding carcinoma invasion and metastasis -- Epithelial-mesenchymal transition (EMT) -- Heterotypic signals in tumor growth and progression -- EMT-inducing transcription factors -- Transgenic model of breast cancer pathogenesis.…”
Get full text
Series

Genetics of tumor metastasis part 2 of 2 /

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Macrophages a cellular toolbox used by tumors to promote progression and metastasis /

Table of Contents: “…Contents: Tumor microenvironment -- Macrophages promote tumor progression and metastasis -- Macrophage densities correlate with poor prognosis in many human cancers -- Macrophages regulate tumor cell migration and intravasation -- Macrophages regulate the angiogenic switch at the malignant transition -- Macrophage and tumor cells move using a paracrine mechanism involving CSF-1 and EGF -- Macrophages synthesize VEGF to regulate angiogenesis.…”
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Invasion, metastasis and stem cells

Table of Contents: “…Contents: Vogelstein-Kinzler model of multi-step colon cancer pathogenesis -- Cell of origin determines tumor morphology and behaviour -- Hierarchical organization of normal epithelial tissues -- Similar hierarchical organization of cancer cells in a tumor -- The invasion-metastasis cascade -- Physical dissemination -- Adaptation to and proliferation in a foreign tissue -- Colonization -- Epithelial-mesenchymal transition (EMT) -- The microenvironment of the primary tumor -- Twist transcription factor -- Slug TF -- What is the nature of cells generated by an EMT? …”
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Invasion, metastasis and stem cells

Table of Contents: “…Contents: Vogelstein-Kinzler model of multi-step colon cancer pathogenesis -- Cell of origin determines tumor morphology and behaviour -- Hierarchical organization of normal epithelial tissues -- Similar hierarchical organization of cancer cells in a tumor -- The invasion-metastasis cascade -- Physical dissemination -- Adaptation to and proliferation in a foreign tissue -- Colonization -- Epithelial-mesenchymal transition (EMT) -- The microenvironment of the primary tumor -- Twist transcription factor -- Slug TF -- What is the nature of cells generated by an EMT? …”
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Invasion, metastasis and stem cells

Table of Contents: “…Contents: Vogelstein-Kinzler model of multi-step colon cancer pathogenesis -- Cell of origin determines tumor morphology and behaviour -- Hierarchical organization of normal epithelial tissues -- Similar hierarchical organization of cancer cells in a tumor -- The invasion-metastasis cascade -- Physical dissemination -- Adaptation to and proliferation in a foreign tissue -- Colonization -- Epithelial-mesenchymal transition (EMT) -- The microenvironment of the primary tumor -- Twist transcription factor -- Slug TF -- What is the nature of cells generated by an EMT? …”
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Macrophages a cellular toolbox used by tumors to promote progression and metastasis /

Table of Contents: “…Contents: Tumor microenvironment -- Macrophages promote tumor progression and metastasis -- Macrophage densities correlate with poor prognosis in many human cancers -- Macrophages regulate tumor cell migration and intravasation -- Macrophages regulate the angiogenic switch at the malignant transition -- Macrophage and tumor cells move using a paracrine mechanism involving CSF-1 and EGF -- Macrophages synthesize VEGF to regulate angiogenesis.…”
Get full text
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Macrophages a cellular toolbox used by tumors to promote progression and metastasis /

Table of Contents: “…Contents: Tumor microenvironment -- Macrophages promote tumor progression and metastasis -- Macrophage densities correlate with poor prognosis in many human cancers -- Macrophages regulate tumor cell migration and intravasation -- Macrophages regulate the angiogenic switch at the malignant transition -- Macrophage and tumor cells move using a paracrine mechanism involving CSF-1 and EGF -- Macrophages synthesize VEGF to regulate angiogenesis.…”
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How tumor-microenvironment interactions drive or inhibit metastasis

Table of Contents: “…Contents: Tumor Organismal Environment (TOE) and Tumor Microenvironment (TME) -- Principles of intra-TME interactions -- Tumor progression and regression -- Site-specific metastasis -- The pre-metastatic niche -- The metastatic cascade -- Epithelial to Mesenchymal Transition (EMT) -- Targeting tumor-TME interactions -- Immune checkpoint blocking enables TME-infiltrating T cells to kill tumor cells.…”
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How tumor-microenvironment interactions drive or inhibit metastasis

Table of Contents: “…Contents: Tumor Organismal Environment (TOE) and Tumor Microenvironment (TME) -- Principles of intra-TME interactions -- Tumor progression and regression -- Site-specific metastasis -- The pre-metastatic niche -- The metastatic cascade -- Epithelial to Mesenchymal Transition (EMT) -- Targeting tumor-TME interactions -- Immune checkpoint blocking enables TME-infiltrating T cells to kill tumor cells.…”
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Management of the N0 neck

Table of Contents: “…Contents: Patterns of spread of oral cancer -- Prognosis with metastatic neck disease -- Risk of occult metastasis -- Predictors of metastasis -- Tumour depth -- Perineural invasion -- Imaging of the node negative neck -- Sentinel lymph node biopsy -- Survival benefits of neck dissection.…”
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Management of the N0 neck

Table of Contents: “…Contents: Patterns of spread of oral cancer -- Prognosis with metastatic neck disease -- Risk of occult metastasis -- Predictors of metastasis -- Tumour depth -- Perineural invasion -- Imaging of the node negative neck -- Sentinel lymph node biopsy -- Survival benefits of neck dissection.…”
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Management of the N0 neck

Table of Contents: “…Contents: Patterns of spread of oral cancer -- Prognosis with metastatic neck disease -- Risk of occult metastasis -- Predictors of metastasis -- Tumour depth -- Perineural invasion -- Imaging of the node negative neck -- Sentinel lymph node biopsy -- Survival benefits of neck dissection.…”
Get full text
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